CA2398571A1 - Materials and methods for treating ocular-related disorders - Google Patents
Materials and methods for treating ocular-related disorders Download PDFInfo
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- CA2398571A1 CA2398571A1 CA002398571A CA2398571A CA2398571A1 CA 2398571 A1 CA2398571 A1 CA 2398571A1 CA 002398571 A CA002398571 A CA 002398571A CA 2398571 A CA2398571 A CA 2398571A CA 2398571 A1 CA2398571 A1 CA 2398571A1
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| US18174300P | 2000-02-11 | 2000-02-11 | |
| US60/181,743 | 2000-02-11 | ||
| US09/599,997 US6821775B1 (en) | 2000-02-11 | 2000-06-23 | Viral vector encoding pigment epithelium-derived factor |
| US09/599,997 | 2000-06-23 | ||
| US22833700P | 2000-08-28 | 2000-08-28 | |
| US60/228,337 | 2000-08-28 | ||
| PCT/US2001/004203 WO2001058494A2 (en) | 2000-02-11 | 2001-02-09 | Gene therapy for treating ocular-related disorders |
Publications (1)
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| CA2398571A1 true CA2398571A1 (en) | 2001-08-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002398571A Abandoned CA2398571A1 (en) | 2000-02-11 | 2001-02-09 | Materials and methods for treating ocular-related disorders |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1253948A2 (https=) |
| JP (1) | JP2003522160A (https=) |
| AU (1) | AU780634C (https=) |
| CA (1) | CA2398571A1 (https=) |
| WO (1) | WO2001058494A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7470659B2 (en) | 2001-12-07 | 2008-12-30 | The Regents Of The University Of California | Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM) |
| JP2006516027A (ja) * | 2002-12-02 | 2006-06-15 | ジェンベク、インコーポレイティッド | 眼関連障害の治療用材料および治療方法 |
| US20040166091A1 (en) | 2003-02-24 | 2004-08-26 | Genvec, Inc. | Materials and methods for treating disorders of the ear |
| WO2006054278A2 (en) | 2004-11-16 | 2006-05-26 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Variants of pigment epithelium derived factor and uses thereof |
| WO2006123248A2 (en) * | 2005-04-18 | 2006-11-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Improved methods and devices for delivering a therapeutic product to the ocular sphere of a subject |
| JP2007291009A (ja) * | 2006-04-25 | 2007-11-08 | Seitai Shigen Laboratory Inc | 血管内膜肥厚抑制剤 |
| WO2009126894A2 (en) * | 2008-04-11 | 2009-10-15 | Massachusetts Eye And Ear Infirmary | Methods and compositions for the diagnosis and treatment of angiogenic disorders |
| CN104619727B (zh) * | 2012-06-25 | 2019-04-05 | 布里格姆及妇女医院股份有限公司 | 靶向治疗 |
| US9790264B2 (en) | 2012-06-25 | 2017-10-17 | The Brigham And Women's Hospital, Inc. | Compounds and methods for modulating pharmacokinetics |
| ES2667209T3 (es) * | 2013-03-14 | 2018-05-10 | Asklepios Biopharmaceutical, Inc. | Genes del receptor-1 de VEGF soluble modificado y vectores para terapia génica |
| TWI710635B (zh) | 2014-10-09 | 2020-11-21 | 美商珍維克公司 | 編碼人類無調同源物-1(hath1)之腺病毒載體 |
| US12305185B2 (en) | 2018-01-23 | 2025-05-20 | Mount Spec Investments Pty Ltd | Expression vector and method |
| US10632211B2 (en) | 2018-06-11 | 2020-04-28 | The Regents Of The University Of California | Demethylation to treat eye disease |
| CN112566622A (zh) * | 2018-06-19 | 2021-03-26 | 细胞疗法有限责任公司 | 用于治疗青光眼或高眼压症的包含眼内压降低剂、cnp化合物、npr-b化合物、tie-2激动剂或神经营养剂的缓释药物递送系统 |
| WO2019246141A1 (en) | 2018-06-19 | 2019-12-26 | Cella Therapeutics, Llc | DRUG DELIVERY SYSTEMS COMPRISING A NEUROTROPHIC AGENT, AN APOPTOSIS SIGNALING FRAGMENT INHIBITOR (FAS) OR FAS LIGAND (FASL) INHIBITOR, A TUMOR NECROSIS FACTOR-α (TNF-α) OR TNF RECEPTOR INHIBITOR, A MITOCHONDRIAL PEPTIDE, AN OLIGONUCLEOTIDE, A CHEMOKINE INHIBITOR, OR A CYSTEINE-ASPARTIC PROTEASE |
| CN118767143A (zh) | 2019-12-12 | 2024-10-15 | 听治疗有限责任公司 | 用于预防和治疗听力损失的组合物和方法 |
| US20230094423A1 (en) * | 2019-12-18 | 2023-03-30 | Cella Therapeutics, Llc | Drug delivery systems comprising a neurotrophic agent, an apoptosis signaling fragment inhibitor (fas) or fas ligand (fasl) inhibitor, a tumor necrosis factor-alpha (tnf-alpha) or tnf receptor inhibitor, a mitochondrial peptide, an oligonucleotide, a chemokine inhibitor, or a cysteine-aspartic protease inhibitor |
Family Cites Families (8)
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| US6319687B1 (en) * | 1992-09-24 | 2001-11-20 | The United States Of America As Represented By The Department Of Health And Human Services | Pigment epithelium-derived factor: characterization, genomic organization and sequence of PEDF gene |
| US5840686A (en) * | 1992-09-24 | 1998-11-24 | The United States Of America As Represented By The Department Of Health And Human Services | Pigment epithelium-derived factor: characterization of its novel biological activity and sequences encoding and expressing the protein and methods of use |
| US5461749A (en) * | 1994-05-31 | 1995-10-31 | Minnesota Mining And Manufacturing Company | Floor mop and cleaning system |
| US5904144A (en) * | 1996-03-22 | 1999-05-18 | Cytotherapeutics, Inc. | Method for treating ophthalmic diseases |
| CA2298018C (en) * | 1997-07-23 | 2008-12-16 | Northwestern University | Methods and compositions for inhibiting angiogenesis |
| JP2001517455A (ja) * | 1997-09-23 | 2001-10-09 | ジェンベク、インコーポレイティッド | 真核生物ウイルスベクター構築用プラスミド |
| WO1999026480A1 (en) * | 1997-11-20 | 1999-06-03 | Genetix Pharmaceuticals, Inc. | Anti-angiogenic gene therapy vectors and their use in treating angiogenesis-related diseases |
| AU3755900A (en) * | 1999-03-15 | 2000-10-04 | Chiron Corporation | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
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2001
- 2001-02-09 JP JP2001557602A patent/JP2003522160A/ja active Pending
- 2001-02-09 EP EP01909022A patent/EP1253948A2/en not_active Withdrawn
- 2001-02-09 AU AU36818/01A patent/AU780634C/en not_active Ceased
- 2001-02-09 CA CA002398571A patent/CA2398571A1/en not_active Abandoned
- 2001-02-09 WO PCT/US2001/004203 patent/WO2001058494A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003522160A (ja) | 2003-07-22 |
| AU780634B2 (en) | 2005-04-07 |
| WO2001058494A2 (en) | 2001-08-16 |
| AU780634C (en) | 2006-02-23 |
| WO2001058494A3 (en) | 2002-04-04 |
| EP1253948A2 (en) | 2002-11-06 |
| AU3681801A (en) | 2001-08-20 |
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