CA2398571A1 - Materials and methods for treating ocular-related disorders - Google Patents
Materials and methods for treating ocular-related disorders Download PDFInfo
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- CA2398571A1 CA2398571A1 CA002398571A CA2398571A CA2398571A1 CA 2398571 A1 CA2398571 A1 CA 2398571A1 CA 002398571 A CA002398571 A CA 002398571A CA 2398571 A CA2398571 A CA 2398571A CA 2398571 A1 CA2398571 A1 CA 2398571A1
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| US18174300P | 2000-02-11 | 2000-02-11 | |
| US60/181,743 | 2000-02-11 | ||
| US09/599,997 US6821775B1 (en) | 2000-02-11 | 2000-06-23 | Viral vector encoding pigment epithelium-derived factor |
| US09/599,997 | 2000-06-23 | ||
| US22833700P | 2000-08-28 | 2000-08-28 | |
| US60/228,337 | 2000-08-28 | ||
| PCT/US2001/004203 WO2001058494A2 (en) | 2000-02-11 | 2001-02-09 | Gene therapy for treating ocular-related disorders |
Publications (1)
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| CA2398571A1 true CA2398571A1 (en) | 2001-08-16 |
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| CA002398571A Abandoned CA2398571A1 (en) | 2000-02-11 | 2001-02-09 | Materials and methods for treating ocular-related disorders |
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| EP (1) | EP1253948A2 (enExample) |
| JP (1) | JP2003522160A (enExample) |
| AU (1) | AU780634C (enExample) |
| CA (1) | CA2398571A1 (enExample) |
| WO (1) | WO2001058494A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7470659B2 (en) | 2001-12-07 | 2008-12-30 | The Regents Of The University Of California | Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM) |
| AU2003297607A1 (en) * | 2002-12-02 | 2004-06-23 | Genvec, Inc | Materials and methods for treating ocular-related disorders |
| US20040166091A1 (en) * | 2003-02-24 | 2004-08-26 | Genvec, Inc. | Materials and methods for treating disorders of the ear |
| CA2588093A1 (en) | 2004-11-16 | 2006-05-26 | Rony Seger | Variants of pigment epithelium derived factor and uses thereof |
| WO2006123248A2 (en) * | 2005-04-18 | 2006-11-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Improved methods and devices for delivering a therapeutic product to the ocular sphere of a subject |
| JP2007291009A (ja) * | 2006-04-25 | 2007-11-08 | Seitai Shigen Laboratory Inc | 血管内膜肥厚抑制剤 |
| WO2009126894A2 (en) * | 2008-04-11 | 2009-10-15 | Massachusetts Eye And Ear Infirmary | Methods and compositions for the diagnosis and treatment of angiogenic disorders |
| EP3369747A1 (en) * | 2012-06-25 | 2018-09-05 | The Brigham and Women's Hospital, Inc. | Targeted theratpeutics |
| US9790264B2 (en) | 2012-06-25 | 2017-10-17 | The Brigham And Women's Hospital, Inc. | Compounds and methods for modulating pharmacokinetics |
| US10385112B2 (en) | 2013-03-14 | 2019-08-20 | Asklepios Biopharmaceutical, Inc. | Modified soluble VEGF receptor-1 genes and vectors for gene therapy |
| TWI710635B (zh) | 2014-10-09 | 2020-11-21 | 美商珍維克公司 | 編碼人類無調同源物-1(hath1)之腺病毒載體 |
| US12305185B2 (en) | 2018-01-23 | 2025-05-20 | Mount Spec Investments Pty Ltd | Expression vector and method |
| KR102785135B1 (ko) | 2018-06-11 | 2025-03-21 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 눈 질환을 치료하는 탈메틸화 |
| CA3104472C (en) * | 2018-06-19 | 2025-12-16 | Cella Therapeutics, Llc | Drug delivery systems comprising active pharmaceutical ingredients and a sustained delevery component |
| AU2019288296B2 (en) * | 2018-06-19 | 2022-11-24 | Cella Therapeutics, Llc | Sustained-release drug delivery systems comprising an intraocular pressure lowering agent, a CNP compound, an NPR-B compound, a Tie-2 agonist, or neurotrophic agent for use for treating glaucoma or ocular hypertension |
| JP7769388B2 (ja) | 2019-12-12 | 2025-11-13 | ティン セラピューティクス，インコーポレイテッド | 聴覚損失の予防及び治療のための組成物及び方法 |
| KR20220118499A (ko) * | 2019-12-18 | 2022-08-25 | 셀라 테라퓨틱스, 엘엘씨 | 신경영양제, 세포자멸 신호전달 단편 억제제(FAS) 또는 FAS 리간드(FASL) 억제제, 종양 괴사 인자-α(TNF-α) 또는 TNF 수용체 억제제, 미토콘드리아 펩티드, 올리고뉴클레오티드, 케모카인 억제제 또는 시스테인-아스파틱 프로테아제 억제제를 포함하는 약물 전달 시스템 |
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| US5840686A (en) * | 1992-09-24 | 1998-11-24 | The United States Of America As Represented By The Department Of Health And Human Services | Pigment epithelium-derived factor: characterization of its novel biological activity and sequences encoding and expressing the protein and methods of use |
| US6319687B1 (en) * | 1992-09-24 | 2001-11-20 | The United States Of America As Represented By The Department Of Health And Human Services | Pigment epithelium-derived factor: characterization, genomic organization and sequence of PEDF gene |
| US5461749A (en) * | 1994-05-31 | 1995-10-31 | Minnesota Mining And Manufacturing Company | Floor mop and cleaning system |
| US5904144A (en) * | 1996-03-22 | 1999-05-18 | Cytotherapeutics, Inc. | Method for treating ophthalmic diseases |
| JP2001510804A (ja) * | 1997-07-23 | 2001-08-07 | ノースウエスタン・ユニバーシテイ | 血管新生を阻害するための方法及び組成物 |
| CA2304173A1 (en) * | 1997-09-23 | 1999-04-01 | Genvec, Inc. | Plasmids for construction of eukaryotic viral vectors |
| WO1999026480A1 (en) * | 1997-11-20 | 1999-06-03 | Genetix Pharmaceuticals, Inc. | Anti-angiogenic gene therapy vectors and their use in treating angiogenesis-related diseases |
| AU3755900A (en) * | 1999-03-15 | 2000-10-04 | Chiron Corporation | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
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2001
- 2001-02-09 JP JP2001557602A patent/JP2003522160A/ja active Pending
- 2001-02-09 WO PCT/US2001/004203 patent/WO2001058494A2/en not_active Ceased
- 2001-02-09 EP EP01909022A patent/EP1253948A2/en not_active Withdrawn
- 2001-02-09 CA CA002398571A patent/CA2398571A1/en not_active Abandoned
- 2001-02-09 AU AU36818/01A patent/AU780634C/en not_active Ceased
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| WO2001058494A3 (en) | 2002-04-04 |
| AU780634B2 (en) | 2005-04-07 |
| AU3681801A (en) | 2001-08-20 |
| AU780634C (en) | 2006-02-23 |
| EP1253948A2 (en) | 2002-11-06 |
| WO2001058494A2 (en) | 2001-08-16 |
| JP2003522160A (ja) | 2003-07-22 |
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