CA2394194C - Rapid tissue processor - Google Patents

Rapid tissue processor Download PDF

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Publication number
CA2394194C
CA2394194C CA002394194A CA2394194A CA2394194C CA 2394194 C CA2394194 C CA 2394194C CA 002394194 A CA002394194 A CA 002394194A CA 2394194 A CA2394194 A CA 2394194A CA 2394194 C CA2394194 C CA 2394194C
Authority
CA
Canada
Prior art keywords
reaction chamber
tissue
microwave
tissue specimen
microwave unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002394194A
Other languages
English (en)
French (fr)
Other versions
CA2394194A1 (en
Inventor
Ervin Essenfeld
Harold Essenfeld
Azorides R. Morales
Harold D. Kimrey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Miami
Original Assignee
University of Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Miami filed Critical University of Miami
Publication of CA2394194A1 publication Critical patent/CA2394194A1/en
Application granted granted Critical
Publication of CA2394194C publication Critical patent/CA2394194C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00—Heating by electric, magnetic or electromagnetic fields
    • H05B6/64—Heating using microwaves
    • H05B6/80—Apparatus for specific applications
    • H05B6/806—Apparatus for specific applications for laboratory use
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/44—Sample treatment involving radiation, e.g. heat
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00—Heating by electric, magnetic or electromagnetic fields
    • H05B6/64—Heating using microwaves
    • H05B6/70—Feed lines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00524—Mixing by agitating sample carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Electromagnetism (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Constitution Of High-Frequency Heating (AREA)
  • Surgical Instruments (AREA)
  • Processing Of Meat And Fish (AREA)
  • Disintegrating Or Milling (AREA)
  • Electrotherapy Devices (AREA)
  • Radiation-Therapy Devices (AREA)
CA002394194A 1999-12-14 2000-12-14 Rapid tissue processor Expired - Lifetime CA2394194C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17054599P 1999-12-14 1999-12-14
US60/170,545 1999-12-14
PCT/US2000/033760 WO2001044783A1 (en) 1999-12-14 2000-12-14 Rapid tissue processor

Publications (2)

Publication Number Publication Date
CA2394194A1 CA2394194A1 (en) 2001-06-21
CA2394194C true CA2394194C (en) 2009-08-25

Family

ID=22620292

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002394194A Expired - Lifetime CA2394194C (en) 1999-12-14 2000-12-14 Rapid tissue processor

Country Status (11)

Country Link
US (1) US20010043884A1 (enExample)
EP (1) EP1238256B1 (enExample)
JP (1) JP2003517601A (enExample)
KR (1) KR100743727B1 (enExample)
AT (1) ATE331946T1 (enExample)
AU (2) AU773429B2 (enExample)
CA (1) CA2394194C (enExample)
DE (1) DE60029129T2 (enExample)
DK (1) DK1238256T3 (enExample)
ES (1) ES2263509T3 (enExample)
WO (2) WO2001044783A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1292818B1 (en) 2000-06-09 2016-01-13 The University Of Miami Pathology grossing board
US7297311B2 (en) * 2001-06-29 2007-11-20 Sysmex Corporation Automatic smear preparing apparatus and automatic sample analysis system having the same
GB0117919D0 (en) * 2001-07-23 2001-09-12 Thermo Shandon Ltd Processor device with fume extraction
ATE551606T1 (de) 2001-10-01 2012-04-15 Leica Biosystems Melbourne Pty Gewebeprozessor zur behandlung histologischer gewebepräparate
DE10149345B4 (de) 2001-10-06 2007-11-15 Leica Mikrosysteme Gmbh Vorrichtung zur schnellen Gewebepräparation für histologische Untersuchungen
US7468161B2 (en) * 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
US7138226B2 (en) 2002-05-10 2006-11-21 The University Of Miami Preservation of RNA and morphology in cells and tissues
AU2003900924A0 (en) * 2003-02-28 2003-03-13 Medsaic Pty Ltd Imaging device
WO2005001437A1 (en) * 2003-06-30 2005-01-06 Academisch Ziekenhuis Groningen Method for histoprocessing
WO2005031312A1 (en) 2003-09-29 2005-04-07 Vision Biosystems Limited System and method for histological tissue specimen processing
EP1676117B1 (en) * 2003-10-24 2009-09-09 The University Of Miami Simplified tissue processing
US8236255B2 (en) 2004-12-02 2012-08-07 Lab Vision Corporation Slide treatment apparatus and methods for use
JP4559889B2 (ja) * 2005-03-24 2010-10-13 株式会社常光 脱灰・脱脂用容器蓋
JP4549912B2 (ja) * 2005-03-28 2010-09-22 株式会社常光 生体組織処理装置
WO2007016935A1 (en) 2005-07-29 2007-02-15 Histogenex Nv Methods, reagents and instrumentation for preparing impregnated tissue samples suitable for histopathological and molecular studies
JP5308156B2 (ja) 2005-09-06 2013-10-09 レイカ バイオシステムズ メルボルン ピーティーワイ リミテッド 組織標本の処理方法及び処理装置
JP2007093254A (ja) * 2005-09-27 2007-04-12 Jokoh Co Ltd 迅速脱灰・脱脂・固定装置
JP2007093255A (ja) * 2005-09-27 2007-04-12 Jokoh Co Ltd 脱灰・脱脂用容器蓋
US20070202607A1 (en) * 2006-02-24 2007-08-30 Revesz Robert N Filtration apparatus and associated method for microwave-assisted chemistry
WO2007141888A1 (ja) * 2006-06-05 2007-12-13 Jokoh Co., Ltd 生物組織固定装置
US20080026366A1 (en) * 2006-06-07 2008-01-31 Newcomer Supply, Inc. Biological fixative and method of using the biological fixative
AT504371B8 (de) * 2006-10-03 2008-09-15 Leica Mikrosysteme Gmbh Vorrichtung zur mikrowellen-gestützten präparation von proben
WO2008074073A1 (en) * 2006-12-18 2008-06-26 Leica Biosystems Melbourne Pty Ltd Device and method for tissue handling and embedding
EP2278295A1 (en) * 2009-07-24 2011-01-26 Milestone S.r.l. Single cavity tissue histology tissue-processor
US20110045565A1 (en) * 2009-08-18 2011-02-24 Leica Biosystems Nussloch Gmbh Apparatus and method for accelerated tissue infiltration by means of microwave excitation
US8067241B2 (en) * 2009-08-26 2011-11-29 General Electric Company Method and apparatus for antigen retrieval process
JP5858435B2 (ja) * 2010-03-12 2016-02-10 国立研究開発法人理化学研究所 生物材料用透明化試薬、及びその利用
DE102011055120B4 (de) * 2011-04-20 2016-04-14 Leica Biosystems Nussloch Gmbh Verfahren zur Verarbeitung zumindest einer histologischen Probe und Vorrichtung zum Behandeln einer histologischen Probe.
EP2518468B1 (en) * 2011-04-26 2019-07-24 Milestone S.r.l. Method, processor and carrier for processing frozen slices of tissue of biospecimens
EP2711682B1 (en) * 2011-05-20 2019-07-10 Riken Clarifying reagent for biological materials and use thereof
AU2012315744B2 (en) * 2011-09-29 2015-09-24 The University Of Miami Ultra-rapid diagnostic tissue preparation as an alternative to frozen section
JP2014209090A (ja) * 2013-03-29 2014-11-06 シスメックス株式会社 細胞分析方法及び装置
JP6433901B2 (ja) 2013-08-14 2018-12-05 国立研究開発法人理化学研究所 光透過性に優れた生物材料を調製するための組成物およびその利用
CN106644652B (zh) * 2017-01-23 2020-01-03 山东省农业科学院蔬菜花卉研究所 一种生物组织自动脱水透明系统
CN106979878B (zh) * 2017-05-09 2023-12-15 贵阳德漫多医疗科技有限公司 一种组织病理标本处理系统
WO2019129646A1 (en) * 2017-12-29 2019-07-04 F. Hoffmann-La Roche Ag Tissue sample preparation system
DE102019109807A1 (de) * 2019-04-12 2020-10-15 K Line Europe Gmbh Verfahren zum wiederholten Aktivieren einer kieferorthopädischen Korrekturvorrichtung
DE102021105932B4 (de) 2021-03-11 2023-02-16 Leica Biosystems Nussloch Gmbh Verfahren zur Gewebeprozessierung und Gewebeprozessor

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5782897A (en) * 1987-06-26 1998-07-21 Microwave Medical Systems, Inc. Microwave heating apparatus for rapid tissue fixation
US5230865A (en) * 1989-09-08 1993-07-27 Cem Corporation Ventable rupture diaphragm-protected container for heating contained materials by microwave radiation
US5696887A (en) * 1991-08-05 1997-12-09 Biotek Solutions, Incorporated Automated tissue assay using standardized chemicals and packages
US5355439A (en) * 1991-08-05 1994-10-11 Bio Tek Instruments Method and apparatus for automated tissue assay
JPH06196257A (ja) * 1992-12-24 1994-07-15 Hitachi Ltd 電子レンジ
US5532462A (en) * 1994-04-29 1996-07-02 Communications & Power Industries Method of and apparatus for heating a reaction vessel with microwave energy
ES2119535T3 (es) * 1996-08-02 1998-10-01 Milestone Srl Procedimiento para procesar muestras organicas.
JPH10172751A (ja) * 1996-12-04 1998-06-26 Matsushita Electric Ind Co Ltd 電子レンジ
DE19652339A1 (de) * 1996-12-17 1998-06-18 Microm Laborgeraete Gmbh Vorrichtung zur Behandlung von Objekten
DK1005633T3 (da) * 1997-08-20 2008-12-15 Univ Miami Vævsfikserings-dehydratiserings-fedtfjernelses-imprægneringsmetode med höj kvalitet og kontinuerligt gennemlöb
JPH11221160A (ja) * 1998-02-10 1999-08-17 Takata Kk 保温器

Also Published As

Publication number Publication date
WO2001044784A1 (en) 2001-06-21
AU773429B2 (en) 2004-05-27
DK1238256T3 (da) 2006-10-30
US20010043884A1 (en) 2001-11-22
DE60029129D1 (de) 2006-08-10
AU2094001A (en) 2001-06-25
WO2001044783A1 (en) 2001-06-21
KR20020082836A (ko) 2002-10-31
KR100743727B1 (ko) 2007-07-30
ES2263509T3 (es) 2006-12-16
CA2394194A1 (en) 2001-06-21
EP1238256A1 (en) 2002-09-11
DE60029129T2 (de) 2006-11-09
JP2003517601A (ja) 2003-05-27
ATE331946T1 (de) 2006-07-15
EP1238256B1 (en) 2006-06-28
AU2727101A (en) 2001-06-25

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Legal Events

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EEER Examination request
MKEX Expiry

Effective date: 20201214