CA2392797A1 - Procede d'identification d'un ligand destine a une molecule cible - Google Patents

Procede d'identification d'un ligand destine a une molecule cible Download PDF

Info

Publication number
CA2392797A1
CA2392797A1 CA002392797A CA2392797A CA2392797A1 CA 2392797 A1 CA2392797 A1 CA 2392797A1 CA 002392797 A CA002392797 A CA 002392797A CA 2392797 A CA2392797 A CA 2392797A CA 2392797 A1 CA2392797 A1 CA 2392797A1
Authority
CA
Canada
Prior art keywords
seq
peptide
target
ligand
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002392797A
Other languages
English (en)
Inventor
David J. Hammond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VI Technologies Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2392797A1 publication Critical patent/CA2392797A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention porte sur des ligands ayant une interaction avec une cible, par exemple, une cible pr~sente sur un virus, et pouvant Útre plus facilement identifi~s si de fausses interactions positives (sp~cifiques ou non sp~cifiques) se diff~rencient de l'interaction sp~cifique d'une cible. L'invention porte ~galement sur un proc~d~ de recherche syst~matique d'une banque de ligands immobilis~s sur une surface et se fixant ~ une cible. Ce proc~d~ peut Útre utilis~ dans plusieurs recherches syst~matiques de la mÚme banque immobilis~e sur une surface pour un nombre de ligands diff~rents.
CA002392797A 1999-12-02 2000-12-01 Procede d'identification d'un ligand destine a une molecule cible Abandoned CA2392797A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45311599A 1999-12-02 1999-12-02
US09/453,115 1999-12-02
PCT/US2000/042515 WO2001040265A2 (fr) 1999-12-02 2000-12-01 Procede d'identification d'un ligand destine a une molecule cible

Publications (1)

Publication Number Publication Date
CA2392797A1 true CA2392797A1 (fr) 2001-06-07

Family

ID=23799267

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002392797A Abandoned CA2392797A1 (fr) 1999-12-02 2000-12-01 Procede d'identification d'un ligand destine a une molecule cible

Country Status (5)

Country Link
EP (1) EP1237908A2 (fr)
JP (1) JP2004500350A (fr)
AU (1) AU4309201A (fr)
CA (1) CA2392797A1 (fr)
WO (1) WO2001040265A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003200922B8 (en) * 1997-10-06 2006-08-31 Trustees Of Tufts College Self-encoding fiber optic sensor
CA2405568A1 (fr) * 2000-04-05 2001-10-18 North Carolina State University Ligands de fixation au prion et procedes d'utilisation correspondants
WO2003062831A1 (fr) * 2002-01-24 2003-07-31 The Regents Of The University Of California Procede destine a determiner des differences entre des interactions moleculaires et a cribler une bibliotheque combinatoire
US7291456B2 (en) 2002-01-24 2007-11-06 The Regents Of The University Of California Method for determining differences in molecular interactions and for screening a combinatorial library
JPWO2003066672A1 (ja) * 2002-02-08 2005-06-09 坂本 賢二 ペプチド
CA2482856A1 (fr) 2002-04-15 2003-10-30 American National Red Cross Ligands de liaison a des proteines plasmatiques
EP1521841B1 (fr) * 2002-07-11 2010-04-14 The American National Red Cross Procede permettant d'identifier des entites actives individuelles dans des melanges complexes
US20050032138A1 (en) * 2003-04-14 2005-02-10 Lathrop Julia T. Method for identifying ligands specific for structural isoforms of proteins
RU2440582C2 (ru) * 2004-12-23 2012-01-20 Ново Нордиск А/С Аффинные лиганды, связывающие антитела
CN101124238A (zh) * 2004-12-23 2008-02-13 诺和诺德公司 结合抗体的亲和性配体
CN104597256B (zh) * 2015-02-14 2016-05-25 河南省农业科学院 一条与牛病毒性腹泻病毒e2蛋白相结合的多肽序列及其应用
WO2023122721A2 (fr) * 2021-12-22 2023-06-29 Oregon State University Peptides pour le ciblage spécifique de types cellulaires de la rétine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516889A (en) * 1993-06-21 1996-05-14 University Technologies International, Inc. Synthetic thrombin receptor peptides
US5834318A (en) * 1995-05-10 1998-11-10 Bayer Corporation Screening of combinatorial peptide libraries for selection of peptide ligand useful in affinity purification of target proteins
AT403477B (de) * 1996-04-30 1998-02-25 Immuno Ag Biologisches material frei von viralen und molekularen pathogenen und verfahren zur herstellung
FI962269A (fi) * 1996-05-30 1997-12-01 Univ Helsinki Licensing Järjestelmä taudin aiheuttajia estävien peptidien seulomiseksi ja taudin aiheuttajien neutralisointikohtien kuvaamiseksi
US6238860B1 (en) * 1998-11-05 2001-05-29 Dyax Corp. Binding moieties for human parvovirus B19

Also Published As

Publication number Publication date
WO2001040265A2 (fr) 2001-06-07
EP1237908A2 (fr) 2002-09-11
AU4309201A (en) 2001-06-12
JP2004500350A (ja) 2004-01-08
WO2001040265A3 (fr) 2002-07-04

Similar Documents

Publication Publication Date Title
US7217507B2 (en) Method for detecting ligands and targets in a mixture
AU716309B2 (en) Screening of combinatorial peptide libraries for selection of peptide ligand useful in affinitypurification of target proteins
Min et al. Peptide arrays: towards routine implementation
US20020155106A1 (en) Method of identifying a ligand for a target molecule
CA2392797A1 (fr) Procede d'identification d'un ligand destine a une molecule cible
Komnatnyy et al. Bead-based screening in chemical biology and drug discovery
Mendes et al. Optimization of the magnetic recovery of hits from one-bead–one-compound library screens
WO1997042507A1 (fr) Serie de peptides et procede associe
PT1255716E (pt) Síntese de segmentos
Kunys et al. Specificity Profiling of Protein‐Binding Domains Using One‐Bead‐One‐Compound Peptide Libraries
CA2390778A1 (fr) Rejet d'organe transplante et etats pathologiques associes
CA2491969A1 (fr) Procede permettant d'identifier des entites actives individuelles dans des melanges complexes
CA2518632C (fr) Criblage
JP2021054848A (ja) 系統的な探索、成熟化および伸長プロセスにより同定した、タンパク質に対する特異的ペプチドバインダー
US7291456B2 (en) Method for determining differences in molecular interactions and for screening a combinatorial library
US20030082560A1 (en) Method of making interactive protein arrays
Tu et al. Combinatorial search for diagnostic agents: Lyme antibody H9724 as an example
US6569636B2 (en) Assay for modulators of metallo-enzyme activity
Kumaresan et al. Screening chemical microarrays: methods and applications
JPH11209394A (ja) フイブリノーゲンのアフイニテイー精製のためのペプチドリガンド
WO1997001098A1 (fr) Procede de detection, quantification et/ou identification d'un peptide
Jafari Exploration of the Applications of One-Bead One-Compound Combinatorial Libraries in Probe Development and Drug Discovery
WO2003062831A1 (fr) Procede destine a determiner des differences entre des interactions moleculaires et a cribler une bibliotheque combinatoire
Stevens System and method for a parallel immunoassay system

Legal Events

Date Code Title Description
FZDE Discontinued