CA2390815A1 - Procede relatif a l'elaboration d'acides .alpha.-hydroxy optiquement actifs, y compris leurs derives - Google Patents

Procede relatif a l'elaboration d'acides .alpha.-hydroxy optiquement actifs, y compris leurs derives Download PDF

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Publication number
CA2390815A1
CA2390815A1 CA002390815A CA2390815A CA2390815A1 CA 2390815 A1 CA2390815 A1 CA 2390815A1 CA 002390815 A CA002390815 A CA 002390815A CA 2390815 A CA2390815 A CA 2390815A CA 2390815 A1 CA2390815 A1 CA 2390815A1
Authority
CA
Canada
Prior art keywords
alkyl
formula
unsubstituted
hept
diisopropyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002390815A
Other languages
English (en)
Inventor
Biing-Jiun Uang
Jia-Wen Chang
Der-Pin Jang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scinopharm Singapore Pte Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2390815A1 publication Critical patent/CA2390815A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

L'invention concerne un procédé relatif à l'élaboration d'acides .alpha.-hydroxy optiquement actifs, y compris leurs dérivés, qui consiste à soumettre à une alcoolyse ou à une hydrolyse les 1,3-dioxolanones alkylées de la formule (IV), dans laquelle R¿1? et R¿2? sont identiques ou différents et représentent chacun indépendamment H ou alkyle C¿1-6?; R¿5? est H, alkyle C¿1-16?, ou phényle substitué ou non; et R¿6? est alkyle C¿1-8?, alcényle C¿2-7? ou benzyle substitué ou non, sachant que les 1,3-dioxolanones alkylées en question sont obtenues par utilisation de 10-camphorsulfonamide comme auxiliaire chiral.
CA002390815A 1999-12-02 1999-12-02 Procede relatif a l'elaboration d'acides .alpha.-hydroxy optiquement actifs, y compris leurs derives Abandoned CA2390815A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1999/028440 WO2001040153A1 (fr) 1999-12-02 1999-12-02 PROCEDE RELATIF A L'ELABORATION D'ACIDES α-HYDROXY OPTIQUEMENT ACTIFS, Y COMPRIS LEURS DERIVES

Publications (1)

Publication Number Publication Date
CA2390815A1 true CA2390815A1 (fr) 2001-06-07

Family

ID=22274194

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002390815A Abandoned CA2390815A1 (fr) 1999-12-02 1999-12-02 Procede relatif a l'elaboration d'acides .alpha.-hydroxy optiquement actifs, y compris leurs derives

Country Status (6)

Country Link
EP (1) EP1233939A4 (fr)
JP (1) JP2003515576A (fr)
CN (1) CN1379748A (fr)
AU (1) AU1838900A (fr)
CA (1) CA2390815A1 (fr)
WO (1) WO2001040153A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102234255B (zh) * 2010-05-07 2013-05-08 国立清华大学 2-吗啉基异嵌烷-10-硫醇的制备方法及其所形成的中间物

Also Published As

Publication number Publication date
EP1233939A1 (fr) 2002-08-28
CN1379748A (zh) 2002-11-13
WO2001040153A1 (fr) 2001-06-07
AU1838900A (en) 2001-06-12
JP2003515576A (ja) 2003-05-07
EP1233939A4 (fr) 2003-07-09

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued