CA2390659C - Ny-eso-1 peptide derivatives, and uses thereof - Google Patents

Ny-eso-1 peptide derivatives, and uses thereof Download PDF

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Publication number
CA2390659C
CA2390659C CA002390659A CA2390659A CA2390659C CA 2390659 C CA2390659 C CA 2390659C CA 002390659 A CA002390659 A CA 002390659A CA 2390659 A CA2390659 A CA 2390659A CA 2390659 C CA2390659 C CA 2390659C
Authority
CA
Canada
Prior art keywords
isolated
molecule
seq
cell
hla
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002390659A
Other languages
English (en)
French (fr)
Other versions
CA2390659A1 (en
Inventor
Danila Valmori
Jean-Charles Cerottini
Pedro Romero
Vincenzo Cerundolo
Peter Roderick Dunbar
Ji-Li Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Institute for Cancer Research Ltd
University of Oxford
Original Assignee
Ludwig Institute for Cancer Research Ltd
University of Oxford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/440,621 external-priority patent/US6417165B1/en
Priority claimed from US09/514,036 external-priority patent/US6689742B1/en
Priority claimed from US09/676,005 external-priority patent/US6605711B1/en
Application filed by Ludwig Institute for Cancer Research Ltd, University of Oxford filed Critical Ludwig Institute for Cancer Research Ltd
Publication of CA2390659A1 publication Critical patent/CA2390659A1/en
Application granted granted Critical
Publication of CA2390659C publication Critical patent/CA2390659C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4267Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K40/4269NY-ESO

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002390659A 1999-11-15 2000-11-08 Ny-eso-1 peptide derivatives, and uses thereof Expired - Fee Related CA2390659C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US09/440,621 US6417165B1 (en) 1988-03-27 1999-11-15 NY-ESO-1-peptide derivatives, and uses thereof
US09/440,621 1999-11-15
US09/514,036 US6689742B1 (en) 2000-02-25 2000-02-25 NY-ESO-1 peptide derivatives, and uses thereof
US09/514,036 2000-02-25
US09/676,005 US6605711B1 (en) 1999-11-15 2000-09-29 NY-ESO-1 peptide derivatives, and uses thereof
US09/676,005 2000-09-29
PCT/US2000/042010 WO2001036453A2 (en) 1999-11-15 2000-11-08 Ny-eso-1 nanopeptide derivatives, and uses thereof

Publications (2)

Publication Number Publication Date
CA2390659A1 CA2390659A1 (en) 2001-05-25
CA2390659C true CA2390659C (en) 2010-03-02

Family

ID=27412062

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002390659A Expired - Fee Related CA2390659C (en) 1999-11-15 2000-11-08 Ny-eso-1 peptide derivatives, and uses thereof

Country Status (5)

Country Link
EP (1) EP1230261B1 (enExample)
JP (1) JP4615805B2 (enExample)
AU (1) AU776058B2 (enExample)
CA (1) CA2390659C (enExample)
WO (1) WO2001036453A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9923337D0 (en) * 1999-10-04 1999-12-08 Isis Innovation Binding agents
EP2333065B1 (en) 2000-01-28 2017-03-15 The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services MHC class II restricted T cell epitopes from the cancer antigen NY ESO-1
US7547517B2 (en) 2002-09-27 2009-06-16 Ludwig Institute For Cancer Research MAGE-C2 antigenic peptides and uses thereof
ES2390967T3 (es) * 2004-01-20 2012-11-20 Aichi Prefecture Epítopo/péptido reconocido por LTC específico para Ep-CAM con restricción por ALH-A2402 y su utilización
EP2332971B1 (en) * 2004-06-17 2016-02-17 MannKind Corporation Epitope analogs
US20160017031A1 (en) * 2006-06-01 2016-01-21 Receptor Logic, LLC T cell receptor mimic rl9a
JP2018505152A (ja) 2014-12-23 2018-02-22 アン ブリンブル マーガレット アミノ酸複合体及びペプチド複合体ならびにそれらの使用
WO2017145097A2 (en) 2016-02-26 2017-08-31 Auckland Uniservices Limited Amino acid and peptide conjugates and conjugation process
AU2018323043A1 (en) * 2017-08-30 2020-03-05 Auckland Uniservices Limited Peptide conjugates, conjugation process, and uses thereof
CN112442118B (zh) * 2019-08-30 2023-02-14 深圳普瑞金生物药业股份有限公司 一种tcr及其应用
US20210369828A1 (en) * 2020-05-28 2021-12-02 Case Western Reserve University Plant virus based cancer antigen vaccine
WO2025171250A1 (en) * 2024-02-08 2025-08-14 H. Lee Moffitt Cancer Center And Research Institute, Inc. Nyeso1 tcr for t-cell therapy and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1021535B1 (en) * 1997-10-08 2007-03-07 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Human cancer antigen ny eso-1/cag-3 and gene encoding same

Also Published As

Publication number Publication date
WO2001036453A2 (en) 2001-05-25
JP2003533175A (ja) 2003-11-11
AU3079101A (en) 2001-05-30
CA2390659A1 (en) 2001-05-25
JP4615805B2 (ja) 2011-01-19
EP1230261A2 (en) 2002-08-14
WO2001036453A3 (en) 2001-12-27
EP1230261B1 (en) 2008-06-25
AU776058B2 (en) 2004-08-26

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Effective date: 20181108