CA2390375A1 - Cell analysis and sorting apparatus for manipulation of cells - Google Patents
Cell analysis and sorting apparatus for manipulation of cells Download PDFInfo
- Publication number
- CA2390375A1 CA2390375A1 CA002390375A CA2390375A CA2390375A1 CA 2390375 A1 CA2390375 A1 CA 2390375A1 CA 002390375 A CA002390375 A CA 002390375A CA 2390375 A CA2390375 A CA 2390375A CA 2390375 A1 CA2390375 A1 CA 2390375A1
- Authority
- CA
- Canada
- Prior art keywords
- substrate
- cell
- well
- chamber
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000004458 analytical method Methods 0.000 title abstract description 21
- 230000005684 electric field Effects 0.000 claims abstract description 18
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 88
- 229910052697 platinum Inorganic materials 0.000 claims description 44
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- 101100269850 Caenorhabditis elegans mask-1 gene Proteins 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 206010013710 Drug interaction Diseases 0.000 description 1
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 description 1
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 108700002232 Immediate-Early Genes Proteins 0.000 description 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 1
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- 210000004962 mammalian cell Anatomy 0.000 description 1
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- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
- G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/0005—Field flow fractionation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1415—Control of particle position
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16464399P | 1999-11-10 | 1999-11-10 | |
| US60/164,643 | 1999-11-10 | ||
| PCT/US2000/030815 WO2001035071A2 (en) | 1999-11-10 | 2000-11-10 | Cell analysis and sorting apparatus for manipulation of cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2390375A1 true CA2390375A1 (en) | 2001-05-17 |
Family
ID=22595424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002390375A Abandoned CA2390375A1 (en) | 1999-11-10 | 2000-11-10 | Cell analysis and sorting apparatus for manipulation of cells |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1236032A2 (ja) |
| JP (1) | JP2003514236A (ja) |
| AU (1) | AU1592501A (ja) |
| CA (1) | CA2390375A1 (ja) |
| WO (1) | WO2001035071A2 (ja) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6893836B2 (en) | 2000-11-29 | 2005-05-17 | Picoliter Inc. | Spatially directed ejection of cells from a carrier fluid |
| US20020064808A1 (en) * | 2000-11-29 | 2002-05-30 | Mutz Mitchell W. | Focused acoustic energy for ejecting cells from a fluid |
| EP2359689B1 (en) | 2002-09-27 | 2015-08-26 | The General Hospital Corporation | Microfluidic device for cell separation and use thereof |
| IL154677A0 (en) | 2003-02-27 | 2003-09-17 | Univ Bar Ilan | A method and apparatus for manipulating an individual cell |
| US7888110B2 (en) | 2003-06-26 | 2011-02-15 | Seng Enterprises Ltd. | Pico liter well holding device and method of making the same |
| US9200245B2 (en) | 2003-06-26 | 2015-12-01 | Seng Enterprises Ltd. | Multiwell plate |
| CA2554927A1 (en) | 2004-02-03 | 2005-08-18 | Chemagis Ltd. | Stable amorphous forms of montelukast sodium |
| AU2005221413B2 (en) | 2004-03-08 | 2010-09-23 | Endoart S.A. | Closure system for tubular organs |
| US7403647B2 (en) | 2004-09-13 | 2008-07-22 | Seng Enterprises Ltd. | Method for identifying an image of a well in an image of a well-bearing component |
| EP1866075B1 (en) * | 2005-01-25 | 2010-09-08 | Seng Enterprises Limited | Microfluidic device for studying cells |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| GB0508983D0 (en) | 2005-05-03 | 2005-06-08 | Oxford Gene Tech Ip Ltd | Cell analyser |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| CN108048549B (zh) | 2006-06-14 | 2021-10-26 | 维里纳塔健康公司 | 使用样品拆分和dna标签进行稀有细胞分析 |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| US8372584B2 (en) | 2006-06-14 | 2013-02-12 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
| US20080070792A1 (en) | 2006-06-14 | 2008-03-20 | Roland Stoughton | Use of highly parallel snp genotyping for fetal diagnosis |
| WO2009081409A2 (en) | 2007-12-26 | 2009-07-02 | Seng Enterprises Ltd. | Device for the study of living cells |
| US9145540B1 (en) | 2007-11-15 | 2015-09-29 | Seng Enterprises Ltd. | Device for the study of living cells |
| EP2334812B1 (en) | 2008-09-20 | 2016-12-21 | The Board of Trustees of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| JP2011000079A (ja) * | 2009-06-19 | 2011-01-06 | Univ Of Tokyo | 粒子を操作する方法及びマイクロ流体装置 |
| US9364831B2 (en) | 2009-08-08 | 2016-06-14 | The Regents Of The University Of California | Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting |
| US9176504B2 (en) | 2011-02-11 | 2015-11-03 | The Regents Of The University Of California | High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation |
| US11493428B2 (en) | 2013-03-15 | 2022-11-08 | Gpb Scientific, Inc. | On-chip microfluidic processing of particles |
| CN105452873B (zh) | 2013-03-15 | 2019-01-18 | 加利福尼亚大学董事会 | 高速按需微流体珠滴生成和操控 |
| CN113512522A (zh) | 2013-03-15 | 2021-10-19 | 普林斯顿大学理事会 | 用于高通量纯化的方法和设备 |
| US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
| JP6334274B2 (ja) * | 2014-06-03 | 2018-05-30 | 積水化学工業株式会社 | 懸濁液の移送方法 |
| CA2967135A1 (en) * | 2014-11-19 | 2016-05-26 | Imec Vzw | Microbubble generator device, systems and method to fabricate |
| JP6964590B2 (ja) | 2015-12-30 | 2021-11-10 | バークレー ライツ，インコーポレイテッド | 光学的に駆動される対流及び変位のマイクロ流体デバイス、そのキット及び方法 |
| US11229912B2 (en) | 2018-03-27 | 2022-01-25 | Hewlett-Packard Development Company, L.P. | Particle separation |
| JP2020027068A (ja) * | 2018-08-15 | 2020-02-20 | ソニー株式会社 | 粒子取得方法、粒子捕捉用チャンバ、及び粒子分析システム |
| WO2020223555A1 (en) | 2019-04-30 | 2020-11-05 | Berkeley Lights, Inc. | Methods for encapsulating and assaying cells |
| US11492585B2 (en) | 2019-05-31 | 2022-11-08 | Canon Medical Systems Corporation | Cell identification system and cell identification method |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310674A (en) * | 1982-05-10 | 1994-05-10 | Bar-Ilan University | Apertured cell carrier |
| JP2662215B2 (ja) * | 1986-11-19 | 1997-10-08 | 株式会社日立製作所 | 細胞保持装置 |
| DE19712309A1 (de) * | 1996-11-16 | 1998-05-20 | Nmi Univ Tuebingen | Mikroelementenanordnung, Verfahren zum Kontaktieren von in einer flüssigen Umgebung befindlichen Zellen und Verfahren zum Herstellen einer Mikroelementenanordnung |
| CA2316966C (en) * | 1997-12-17 | 2008-04-08 | Horst Vogel | Positioning and electrophysiological characterization of individual cells and reconstituted membrane systems on microstructured carriers |
-
2000
- 2000-11-10 AU AU15925/01A patent/AU1592501A/en not_active Abandoned
- 2000-11-10 EP EP00978464A patent/EP1236032A2/en not_active Withdrawn
- 2000-11-10 WO PCT/US2000/030815 patent/WO2001035071A2/en active Application Filing
- 2000-11-10 JP JP2001536950A patent/JP2003514236A/ja not_active Withdrawn
- 2000-11-10 CA CA002390375A patent/CA2390375A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001035071A3 (en) | 2002-02-21 |
| EP1236032A2 (en) | 2002-09-04 |
| WO2001035071A2 (en) | 2001-05-17 |
| JP2003514236A (ja) | 2003-04-15 |
| AU1592501A (en) | 2001-06-06 |
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