CA2382848C - Diagnostics and therapeutics for osteoporosis - Google Patents

Diagnostics and therapeutics for osteoporosis Download PDF

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Publication number
CA2382848C
CA2382848C CA2382848A CA2382848A CA2382848C CA 2382848 C CA2382848 C CA 2382848C CA 2382848 A CA2382848 A CA 2382848A CA 2382848 A CA2382848 A CA 2382848A CA 2382848 C CA2382848 C CA 2382848C
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CA
Canada
Prior art keywords
allele
subject
marker
gene
predisposed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2382848A
Other languages
English (en)
French (fr)
Other versions
CA2382848A1 (en
Inventor
Simon Van Dijk
Gordon W. Duff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Interleukin Genetics Inc
Original Assignee
Interleukin Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interleukin Genetics Inc filed Critical Interleukin Genetics Inc
Publication of CA2382848A1 publication Critical patent/CA2382848A1/en
Application granted granted Critical
Publication of CA2382848C publication Critical patent/CA2382848C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2382848A 1999-08-30 2000-08-30 Diagnostics and therapeutics for osteoporosis Expired - Fee Related CA2382848C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15146099P 1999-08-30 1999-08-30
US60/151,460 1999-08-30
PCT/US2000/023844 WO2001016377A2 (en) 1999-08-30 2000-08-30 Diagnostics and therapeutics for osteoporosis

Publications (2)

Publication Number Publication Date
CA2382848A1 CA2382848A1 (en) 2001-03-08
CA2382848C true CA2382848C (en) 2011-01-04

Family

ID=22538869

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2382848A Expired - Fee Related CA2382848C (en) 1999-08-30 2000-08-30 Diagnostics and therapeutics for osteoporosis

Country Status (11)

Country Link
US (2) US6558905B1 (enExample)
EP (1) EP1212464B1 (enExample)
JP (1) JP2004504802A (enExample)
AT (1) ATE318328T1 (enExample)
AU (2) AU785040B2 (enExample)
BR (1) BR0014150A (enExample)
CA (1) CA2382848C (enExample)
DE (1) DE60026150T2 (enExample)
ES (1) ES2261239T3 (enExample)
MX (1) MXPA02002251A (enExample)
WO (1) WO2001016377A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001000880A2 (en) * 1999-06-30 2001-01-04 Interleukin Genetics, Inc. Diagnostics and therapeutics for diseases associated with an il-1 inflammatory haplotype
US20090023147A1 (en) * 1999-08-30 2009-01-22 Kenneth Kornman Diagnostics and therapeutics for osteoporosis
EP1409737A4 (en) * 2001-06-15 2005-10-12 Interleukin Genetics Inc METHODS OF DETECTING AND TREATING EARLY APPEARANCE OF CONDITIONS RELATED TO AGING
US20070264645A1 (en) * 2002-01-25 2007-11-15 Kenneth Kornman IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
CN1751127A (zh) * 2002-01-25 2006-03-22 白介素遗传公司 Il-1基因簇和相关的炎性多态性和单倍型
AU2003265676A1 (en) * 2002-08-24 2004-03-11 Creighton University Methods for detecting genes associated with bone properties and/or height
CA2512549A1 (en) * 2003-01-16 2004-08-05 Decode Genetics Ehf. Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association
AU2004263184B2 (en) * 2003-08-08 2010-12-02 Interleukin Genetics, Inc. Diagnostic and therapeutics for osteoporosis
US7309589B2 (en) 2004-08-20 2007-12-18 Vironix Llc Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing
RU2271827C1 (ru) * 2004-09-28 2006-03-20 Федеральное государственное учреждение"Санкт-Петербургский научно-исследовательский институт уха, горла, носа и речи Федерального агенства по здравоохранению и социальному развитию"(ФГУ "СПбНИИ ЛОР Росздрава") Способ определения тактики лечения рекомбинантным цитокином, регулирующим воспаление
US7353662B2 (en) * 2004-12-22 2008-04-08 York International Corporation Medium voltage starter for a chiller unit
US8590329B2 (en) 2004-12-22 2013-11-26 Johnson Controls Technology Company Medium voltage power controller
EP1951903A2 (en) * 2005-10-25 2008-08-06 Interleukin Genetics, Inc. The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes
EP2089538B1 (en) * 2006-11-15 2013-08-21 Interleukin Genetics, Inc. The il-1 gene cluster and insulin resistance: associated polymorphisms, haplotypes and methods of using same
CA3011363A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10329620B2 (en) 2017-01-12 2019-06-25 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
EP3980561A1 (en) 2019-06-06 2022-04-13 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8311018D0 (en) 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
CA1316520C (en) 1987-05-19 1993-04-20 Larry C. Hamilton Valve
FR2650840B1 (fr) 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
WO1993011149A1 (en) 1991-12-03 1993-06-10 Thomas Jefferson University Methods of detecting a genetic predisposition for osteoporosis
US5593833A (en) 1992-07-31 1997-01-14 Garvan Institute Of Medical Research Assessment of allelic variation in vitamin D receptor correlated to bone density or turnover
DE69333641T2 (de) 1992-12-28 2005-11-03 Baylink, David Jeston, Redlands Methode zur messung der knochenresorption
IL108947A0 (en) 1993-03-12 1994-06-24 Osteopharm Ltd Bone stimulating factor
CA2164498C (en) 1993-07-09 2007-09-11 Paul A. Price Assay for ykl-40 as a marker for degradation of mammalian connective tissue matrices
US5698399A (en) * 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
GB9706359D0 (en) 1997-03-27 1997-05-14 Gemini International Holdings Polymorphisms of an il-1 receptor antagonist gene
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease

Also Published As

Publication number Publication date
ATE318328T1 (de) 2006-03-15
AU2006203097A1 (en) 2006-08-17
AU7338000A (en) 2001-03-26
WO2001016377A3 (en) 2002-01-17
AU785040B2 (en) 2006-08-31
WO2001016377A2 (en) 2001-03-08
EP1212464A2 (en) 2002-06-12
US6558905B1 (en) 2003-05-06
AU2006203097B2 (en) 2009-03-12
BR0014150A (pt) 2002-05-14
JP2004504802A (ja) 2004-02-19
EP1212464B1 (en) 2006-02-22
DE60026150D1 (de) 2006-04-27
MXPA02002251A (es) 2003-08-20
ES2261239T3 (es) 2006-11-16
DE60026150T2 (de) 2006-11-16
US20040110168A1 (en) 2004-06-10
CA2382848A1 (en) 2001-03-08

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