CA2375207A1 - Peptide ayant une fonctionnalite preptine - Google Patents

Peptide ayant une fonctionnalite preptine Download PDF

Info

Publication number
CA2375207A1
CA2375207A1 CA002375207A CA2375207A CA2375207A1 CA 2375207 A1 CA2375207 A1 CA 2375207A1 CA 002375207 A CA002375207 A CA 002375207A CA 2375207 A CA2375207 A CA 2375207A CA 2375207 A1 CA2375207 A1 CA 2375207A1
Authority
CA
Canada
Prior art keywords
preptin
pro
asp
analog
phe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002375207A
Other languages
English (en)
Inventor
Garth James Smith Cooper
Christina Maree Buchanan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PROTEMIX DISCOVERY Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2375207A1 publication Critical patent/CA2375207A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/65Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention porte sur un peptide mammalien bioactif, et notamment sur un peptide sécrété par la cellule .beta. des îlots pancréatiques qui stimule la sécrétion de l'insuline, appelée preptine. L'invention porte entre autre sur des analogues de la preptine, sur des compositions pharmaceutiques contenant la preptine ou ses analogues et sur leur utilisation comme médicaments.
CA002375207A 1999-06-18 2000-06-19 Peptide ayant une fonctionnalite preptine Abandoned CA2375207A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ33635999 1999-06-18
NZ336359 1999-06-18
PCT/NZ2000/000102 WO2000078805A1 (fr) 1999-06-18 2000-06-19 Peptide ayant une fonctionnalite preptine

Publications (1)

Publication Number Publication Date
CA2375207A1 true CA2375207A1 (fr) 2000-12-28

Family

ID=19927343

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002375207A Abandoned CA2375207A1 (fr) 1999-06-18 2000-06-19 Peptide ayant une fonctionnalite preptine

Country Status (7)

Country Link
EP (1) EP1185558A4 (fr)
JP (1) JP2003503019A (fr)
CN (1) CN1296384C (fr)
AU (1) AU759203B2 (fr)
CA (1) CA2375207A1 (fr)
HK (1) HK1042307A1 (fr)
WO (1) WO2000078805A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1324234A (zh) 1998-09-25 2001-11-28 格利科克斯有限公司 果糖胺氧化酶,拮抗剂和抑制剂
EP1487431B1 (fr) 2002-03-08 2012-05-02 PhilERA New Zealand Limited Prevention et/ou traitement de maladie cardio-vasculaire et/ou d'insuffisance cardiaque connexe
EP1534321A1 (fr) * 2002-08-01 2005-06-01 Protemix Corporation Limited Methodes d'utilisation de composes avec une fonction preptine
CA2494305A1 (fr) * 2002-08-01 2004-02-12 Auckland Uniservices Limited Procedes d'utilisation de la preptine
JP2006503014A (ja) 2002-08-20 2006-01-26 プロテミックス コーポレイション リミティド 剤形及び関連する治療法
CA3050047A1 (fr) 2004-07-19 2006-03-16 Philera New Zealand Limited Synthese de triethylenetetramines
US20090054320A1 (en) * 2005-04-20 2009-02-26 Protemix Discovery Limited Vesiculins
US8691760B2 (en) 2009-02-02 2014-04-08 Ramot At Tel-Aviv University Peptides, pharmaceutical compositions comprising same and uses thereof
WO2012017439A2 (fr) 2010-08-04 2012-02-09 Ramot At Tel-Aviv University Ltd. Procédés de traitement de maladies auto-immunes du système nerveux central (snc) et de maladies neurodégénératives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000619A1 (fr) * 1984-07-13 1986-01-30 Chiron Corporation Facteurs de croissance prepro i et ii analogues a l'insuline
GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus
ATE128359T1 (de) * 1988-01-11 1995-10-15 Amylin Pharmaceuticals Inc Behandlung von diabetes mellitus typ 2.
ATE128032T1 (de) * 1989-07-10 1995-10-15 Amylin Pharmaceuticals Inc Verwendung eines amylinantagonisten zur herstellung eines artzneimittels zur behandlung von fettsucht und essentieller hypertonie und damit zusammenhängenden krankheiten.
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions

Also Published As

Publication number Publication date
AU759203B2 (en) 2003-04-10
CN1355813A (zh) 2002-06-26
WO2000078805A1 (fr) 2000-12-28
AU5717800A (en) 2001-01-09
EP1185558A1 (fr) 2002-03-13
JP2003503019A (ja) 2003-01-28
HK1042307A1 (zh) 2002-08-09
EP1185558A4 (fr) 2006-02-15
CN1296384C (zh) 2007-01-24

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead