CA2375207A1 - Peptide ayant une fonctionnalite preptine - Google Patents
Peptide ayant une fonctionnalite preptine Download PDFInfo
- Publication number
- CA2375207A1 CA2375207A1 CA002375207A CA2375207A CA2375207A1 CA 2375207 A1 CA2375207 A1 CA 2375207A1 CA 002375207 A CA002375207 A CA 002375207A CA 2375207 A CA2375207 A CA 2375207A CA 2375207 A1 CA2375207 A1 CA 2375207A1
- Authority
- CA
- Canada
- Prior art keywords
- preptin
- pro
- asp
- analog
- phe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 230000000975 bioactive effect Effects 0.000 claims abstract description 5
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- KCOPOPKJRHVGPE-AQZXSJQPSA-N Asp-Thr-Trp Chemical compound [H]N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O KCOPOPKJRHVGPE-AQZXSJQPSA-N 0.000 claims description 13
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Landscapes
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- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
L'invention porte sur un peptide mammalien bioactif, et notamment sur un peptide sécrété par la cellule .beta. des îlots pancréatiques qui stimule la sécrétion de l'insuline, appelée preptine. L'invention porte entre autre sur des analogues de la preptine, sur des compositions pharmaceutiques contenant la preptine ou ses analogues et sur leur utilisation comme médicaments.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ33635999 | 1999-06-18 | ||
NZ336359 | 1999-06-18 | ||
PCT/NZ2000/000102 WO2000078805A1 (fr) | 1999-06-18 | 2000-06-19 | Peptide ayant une fonctionnalite preptine |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2375207A1 true CA2375207A1 (fr) | 2000-12-28 |
Family
ID=19927343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002375207A Abandoned CA2375207A1 (fr) | 1999-06-18 | 2000-06-19 | Peptide ayant une fonctionnalite preptine |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1185558A4 (fr) |
JP (1) | JP2003503019A (fr) |
CN (1) | CN1296384C (fr) |
AU (1) | AU759203B2 (fr) |
CA (1) | CA2375207A1 (fr) |
HK (1) | HK1042307A1 (fr) |
WO (1) | WO2000078805A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1324234A (zh) | 1998-09-25 | 2001-11-28 | 格利科克斯有限公司 | 果糖胺氧化酶,拮抗剂和抑制剂 |
EP1487431B1 (fr) | 2002-03-08 | 2012-05-02 | PhilERA New Zealand Limited | Prevention et/ou traitement de maladie cardio-vasculaire et/ou d'insuffisance cardiaque connexe |
EP1534321A1 (fr) * | 2002-08-01 | 2005-06-01 | Protemix Corporation Limited | Methodes d'utilisation de composes avec une fonction preptine |
CA2494305A1 (fr) * | 2002-08-01 | 2004-02-12 | Auckland Uniservices Limited | Procedes d'utilisation de la preptine |
JP2006503014A (ja) | 2002-08-20 | 2006-01-26 | プロテミックス コーポレイション リミティド | 剤形及び関連する治療法 |
CA3050047A1 (fr) | 2004-07-19 | 2006-03-16 | Philera New Zealand Limited | Synthese de triethylenetetramines |
US20090054320A1 (en) * | 2005-04-20 | 2009-02-26 | Protemix Discovery Limited | Vesiculins |
US8691760B2 (en) | 2009-02-02 | 2014-04-08 | Ramot At Tel-Aviv University | Peptides, pharmaceutical compositions comprising same and uses thereof |
WO2012017439A2 (fr) | 2010-08-04 | 2012-02-09 | Ramot At Tel-Aviv University Ltd. | Procédés de traitement de maladies auto-immunes du système nerveux central (snc) et de maladies neurodégénératives |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986000619A1 (fr) * | 1984-07-13 | 1986-01-30 | Chiron Corporation | Facteurs de croissance prepro i et ii analogues a l'insuline |
GB8720115D0 (en) * | 1987-08-26 | 1987-09-30 | Cooper G J S | Treatment of diabetes mellitus |
ATE128359T1 (de) * | 1988-01-11 | 1995-10-15 | Amylin Pharmaceuticals Inc | Behandlung von diabetes mellitus typ 2. |
ATE128032T1 (de) * | 1989-07-10 | 1995-10-15 | Amylin Pharmaceuticals Inc | Verwendung eines amylinantagonisten zur herstellung eines artzneimittels zur behandlung von fettsucht und essentieller hypertonie und damit zusammenhängenden krankheiten. |
US5234906A (en) * | 1991-01-10 | 1993-08-10 | Amylin Pharmaceuticals, Inc. | Hyperglycemic compositions |
-
2000
- 2000-06-19 WO PCT/NZ2000/000102 patent/WO2000078805A1/fr active Application Filing
- 2000-06-19 CA CA002375207A patent/CA2375207A1/fr not_active Abandoned
- 2000-06-19 CN CNB008087857A patent/CN1296384C/zh not_active Expired - Fee Related
- 2000-06-19 AU AU57178/00A patent/AU759203B2/en not_active Ceased
- 2000-06-19 JP JP2001505563A patent/JP2003503019A/ja active Pending
- 2000-06-19 EP EP00942575A patent/EP1185558A4/fr not_active Withdrawn
-
2002
- 2002-05-11 HK HK02103568.4A patent/HK1042307A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AU759203B2 (en) | 2003-04-10 |
CN1355813A (zh) | 2002-06-26 |
WO2000078805A1 (fr) | 2000-12-28 |
AU5717800A (en) | 2001-01-09 |
EP1185558A1 (fr) | 2002-03-13 |
JP2003503019A (ja) | 2003-01-28 |
HK1042307A1 (zh) | 2002-08-09 |
EP1185558A4 (fr) | 2006-02-15 |
CN1296384C (zh) | 2007-01-24 |
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Legal Events
Date | Code | Title | Description |
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EEER | Examination request | ||
FZDE | Dead |