CA2375207A1 - Peptide ayant une fonctionnalite preptine - Google Patents
Peptide ayant une fonctionnalite preptine Download PDFInfo
- Publication number
- CA2375207A1 CA2375207A1 CA002375207A CA2375207A CA2375207A1 CA 2375207 A1 CA2375207 A1 CA 2375207A1 CA 002375207 A CA002375207 A CA 002375207A CA 2375207 A CA2375207 A CA 2375207A CA 2375207 A1 CA2375207 A1 CA 2375207A1
- Authority
- CA
- Canada
- Prior art keywords
- preptin
- pro
- asp
- analog
- phe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 230000000975 bioactive effect Effects 0.000 claims abstract description 5
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- KCOPOPKJRHVGPE-AQZXSJQPSA-N Asp-Thr-Trp Chemical compound [H]N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O KCOPOPKJRHVGPE-AQZXSJQPSA-N 0.000 claims description 13
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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Landscapes
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
L'invention porte sur un peptide mammalien bioactif, et notamment sur un peptide sécrété par la cellule .beta. des îlots pancréatiques qui stimule la sécrétion de l'insuline, appelée preptine. L'invention porte entre autre sur des analogues de la preptine, sur des compositions pharmaceutiques contenant la preptine ou ses analogues et sur leur utilisation comme médicaments.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ336359 | 1999-06-18 | ||
| NZ33635999 | 1999-06-18 | ||
| PCT/NZ2000/000102 WO2000078805A1 (fr) | 1999-06-18 | 2000-06-19 | Peptide ayant une fonctionnalite preptine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2375207A1 true CA2375207A1 (fr) | 2000-12-28 |
Family
ID=19927343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002375207A Abandoned CA2375207A1 (fr) | 1999-06-18 | 2000-06-19 | Peptide ayant une fonctionnalite preptine |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1185558A4 (fr) |
| JP (1) | JP2003503019A (fr) |
| CN (1) | CN1296384C (fr) |
| AU (1) | AU759203B2 (fr) |
| CA (1) | CA2375207A1 (fr) |
| HK (1) | HK1042307A1 (fr) |
| WO (1) | WO2000078805A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1324234A (zh) | 1998-09-25 | 2001-11-28 | 格利科克斯有限公司 | 果糖胺氧化酶,拮抗剂和抑制剂 |
| DK2500018T3 (en) | 2002-03-08 | 2017-10-02 | Philera New Zealand Ltd | Prevention and / or treatment of cardiovascular disease and / or associated heart failure |
| CA2494305A1 (fr) * | 2002-08-01 | 2004-02-12 | Auckland Uniservices Limited | Procedes d'utilisation de la preptine |
| WO2004012761A1 (fr) * | 2002-08-01 | 2004-02-12 | Protemix Corporation Limited | Methodes d'utilisation de composes avec une fonction preptine |
| CA2496411A1 (fr) | 2002-08-20 | 2004-03-04 | Protemix Corporation Limited | Formes posologiques et traitements s'y rapportant |
| EP1778618B1 (fr) | 2004-07-19 | 2013-12-25 | PhilERA New Zealand Limited | Synthese de triethylenetetramines |
| US20090054320A1 (en) | 2005-04-20 | 2009-02-26 | Protemix Discovery Limited | Vesiculins |
| WO2010086867A2 (fr) | 2009-02-02 | 2010-08-05 | Ramot At Tel Aviv University Ltd. | Peptides, compositions pharmaceutiques en contenant et leurs utilisations |
| WO2012017439A2 (fr) | 2010-08-04 | 2012-02-09 | Ramot At Tel-Aviv University Ltd. | Procédés de traitement de maladies auto-immunes du système nerveux central (snc) et de maladies neurodégénératives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1986000619A1 (fr) * | 1984-07-13 | 1986-01-30 | Chiron Corporation | Facteurs de croissance prepro i et ii analogues a l'insuline |
| GB8720115D0 (en) * | 1987-08-26 | 1987-09-30 | Cooper G J S | Treatment of diabetes mellitus |
| AU631112B2 (en) * | 1988-01-11 | 1992-11-19 | Amylin Corporation | Treatment of type 2 diabetes mellitus |
| CA2020786A1 (fr) * | 1989-07-10 | 1991-01-11 | Amylin Pharmaceuticals, Inc. | Traitement de l'obesite et de l'hypertension arterielle essentielle et des troubles apparentes |
| US5234906A (en) * | 1991-01-10 | 1993-08-10 | Amylin Pharmaceuticals, Inc. | Hyperglycemic compositions |
-
2000
- 2000-06-19 WO PCT/NZ2000/000102 patent/WO2000078805A1/fr active Application Filing
- 2000-06-19 CA CA002375207A patent/CA2375207A1/fr not_active Abandoned
- 2000-06-19 EP EP00942575A patent/EP1185558A4/fr not_active Withdrawn
- 2000-06-19 AU AU57178/00A patent/AU759203B2/en not_active Ceased
- 2000-06-19 JP JP2001505563A patent/JP2003503019A/ja active Pending
- 2000-06-19 CN CNB008087857A patent/CN1296384C/zh not_active Expired - Fee Related
-
2002
- 2002-05-11 HK HK02103568.4A patent/HK1042307A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1042307A1 (zh) | 2002-08-09 |
| EP1185558A1 (fr) | 2002-03-13 |
| JP2003503019A (ja) | 2003-01-28 |
| EP1185558A4 (fr) | 2006-02-15 |
| CN1296384C (zh) | 2007-01-24 |
| AU759203B2 (en) | 2003-04-10 |
| CN1355813A (zh) | 2002-06-26 |
| AU5717800A (en) | 2001-01-09 |
| WO2000078805A1 (fr) | 2000-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |