CA2362496C - Polypeptide variants with increased heparin-binding ability - Google Patents
Polypeptide variants with increased heparin-binding ability Download PDFInfo
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- CA2362496C CA2362496C CA2362496A CA2362496A CA2362496C CA 2362496 C CA2362496 C CA 2362496C CA 2362496 A CA2362496 A CA 2362496A CA 2362496 A CA2362496 A CA 2362496A CA 2362496 C CA2362496 C CA 2362496C
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Classifications
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Biomedical Technology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19906096A DE19906096A1 (de) | 1999-02-13 | 1999-02-13 | Protein mit einem Heparin-bindenden Epitop |
| DE19906096.7 | 1999-02-13 | ||
| PCT/EP2000/000637 WO2000047736A1 (de) | 1999-02-13 | 2000-01-27 | Polypeptidvarianten mit erhöhter heparin-bindungsfähigkeit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2362496A1 CA2362496A1 (en) | 2000-08-17 |
| CA2362496C true CA2362496C (en) | 2011-04-19 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2362496A Expired - Fee Related CA2362496C (en) | 1999-02-13 | 2000-01-27 | Polypeptide variants with increased heparin-binding ability |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7253254B1 (enExample) |
| EP (1) | EP1151095B1 (enExample) |
| JP (3) | JP4155711B2 (enExample) |
| CN (1) | CN1169959C (enExample) |
| AT (1) | ATE470713T1 (enExample) |
| AU (1) | AU762387B2 (enExample) |
| BR (1) | BR0008785A (enExample) |
| CA (1) | CA2362496C (enExample) |
| DE (2) | DE19906096A1 (enExample) |
| RU (1) | RU2227743C2 (enExample) |
| WO (1) | WO2000047736A1 (enExample) |
Families Citing this family (19)
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| US8734525B2 (en) | 2003-12-31 | 2014-05-27 | Warsaw Orthopedic, Inc. | Osteoinductive demineralized cancellous bone |
| WO2005065396A2 (en) | 2003-12-31 | 2005-07-21 | Osteotech, Inc. | Improved bone matrix compositions and methods |
| DE602005023714D1 (de) * | 2004-02-20 | 2010-11-04 | Biosurface Eng Tech Inc | Positiver modulator des knochenmorphogenetisches protein-2 (bmp-2) |
| EP1885751B1 (en) * | 2005-05-27 | 2011-11-16 | BBS - Bioactive Bone Substitutes Oy | Bone morphogenetic protein 6 containing a heparin binding site and osteogenic devices and pharmaceutical products containing thereof |
| US9216212B2 (en) * | 2005-08-05 | 2015-12-22 | University Of Massachusetts | Virus-like particles as vaccines for paramyxovirus |
| US7951384B2 (en) * | 2005-08-05 | 2011-05-31 | University Of Massachusetts | Virus-like particles as vaccines for paramyxovirus |
| US8992965B2 (en) | 2005-11-01 | 2015-03-31 | Warsaw Orthopedic, Inc. | Bone matrix compositions and methods |
| JP2007332106A (ja) * | 2006-06-16 | 2007-12-27 | Okayama Univ | 骨形成用徐放性医薬組成物 |
| CA2692240C (en) | 2006-06-22 | 2018-03-13 | Biosurface Engineering Technologies, Inc. | Composition and method for delivery of bmp-2 amplifier/co-activator for enhancement of osteogenesis |
| US20080206299A1 (en) * | 2007-02-27 | 2008-08-28 | Shimp Lawrence A | Method for Recovering Minerals From Bone and Use of Same |
| AU2008265850B2 (en) | 2007-06-15 | 2014-06-26 | Warsaw Orthopedic, Inc. | Bone matrix compositions and methods |
| US9554920B2 (en) | 2007-06-15 | 2017-01-31 | Warsaw Orthopedic, Inc. | Bone matrix compositions having nanoscale textured surfaces |
| WO2009009688A1 (en) | 2007-07-10 | 2009-01-15 | Osteotech, Inc. | Delivery system |
| JP2009045142A (ja) * | 2007-08-16 | 2009-03-05 | Okayama Univ | 生体内にて基材周囲に骨形成を誘導するための基材処理方法 |
| WO2010039224A2 (en) | 2008-09-30 | 2010-04-08 | University Of Massachusetts Medical School | Respiratory syncytial virus (rsv) sequences for protein expression and vaccines |
| JP5799409B2 (ja) * | 2008-12-19 | 2015-10-28 | 国立大学法人 新潟大学 | ヘパリン親和性エリスロポエチン |
| US9101475B2 (en) | 2009-02-12 | 2015-08-11 | Warsaw Orthopedic, Inc. | Segmented delivery system |
| GB201601136D0 (en) | 2016-01-21 | 2016-03-09 | Mörgelin Matthias And Abdillahi Suado M | Novel polypeptides and medical uses thereof |
| JP6629488B2 (ja) | 2016-12-30 | 2020-01-15 | バイオジェンド セラピューティクス カンパニー リミテッド | 組換えポリペプチド、核酸分子、それらを含む組成物及びそれらの製造、使用方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4455256A (en) | 1981-05-05 | 1984-06-19 | The Regents Of The University Of California | Bone morphogenetic protein |
| US4804744A (en) | 1984-01-04 | 1989-02-14 | International Genetic Engineering, Inc. | Osteogenic factors |
| NZ210699A (en) | 1984-01-04 | 1989-06-28 | Int Genetic Eng | Isolation of an osteogenic protein of the p3 immunologically related family |
| US4627982A (en) | 1984-07-16 | 1986-12-09 | Collagen Corporation | Partially purified bone-inducing factor |
| US5013649A (en) | 1986-07-01 | 1991-05-07 | Genetics Institute, Inc. | DNA sequences encoding osteoinductive products |
| IL83003A (en) | 1986-07-01 | 1995-07-31 | Genetics Inst | Osteoinductive factors |
| US5187076A (en) | 1986-07-01 | 1993-02-16 | Genetics Institute, Inc. | DNA sequences encoding BMP-6 proteins |
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| US4975526A (en) | 1989-02-23 | 1990-12-04 | Creative Biomolecules, Inc. | Bone collagen matrix for zenogenic implants |
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-
1999
- 1999-02-13 DE DE19906096A patent/DE19906096A1/de not_active Ceased
-
2000
- 2000-01-27 EP EP00901137A patent/EP1151095B1/de not_active Expired - Lifetime
- 2000-01-27 CN CNB008037183A patent/CN1169959C/zh not_active Expired - Fee Related
- 2000-01-27 WO PCT/EP2000/000637 patent/WO2000047736A1/de not_active Ceased
- 2000-01-27 RU RU2001123926/15A patent/RU2227743C2/ru not_active IP Right Cessation
- 2000-01-27 DE DE50015938T patent/DE50015938D1/de not_active Expired - Lifetime
- 2000-01-27 AT AT00901137T patent/ATE470713T1/de not_active IP Right Cessation
- 2000-01-27 AU AU21106/00A patent/AU762387B2/en not_active Ceased
- 2000-01-27 JP JP2000598634A patent/JP4155711B2/ja not_active Expired - Fee Related
- 2000-01-27 CA CA2362496A patent/CA2362496C/en not_active Expired - Fee Related
- 2000-01-27 US US09/913,467 patent/US7253254B1/en not_active Expired - Fee Related
- 2000-01-27 BR BR0008785-8A patent/BR0008785A/pt not_active Application Discontinuation
-
2007
- 2007-10-02 JP JP2007258333A patent/JP2008086319A/ja active Pending
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2008
- 2008-08-05 JP JP2008201668A patent/JP2009011323A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2362496A1 (en) | 2000-08-17 |
| AU2110600A (en) | 2000-08-29 |
| DE19906096A1 (de) | 2000-08-17 |
| JP4155711B2 (ja) | 2008-09-24 |
| JP2002536016A (ja) | 2002-10-29 |
| JP2009011323A (ja) | 2009-01-22 |
| EP1151095B1 (de) | 2010-06-09 |
| BR0008785A (pt) | 2001-11-06 |
| EP1151095A1 (de) | 2001-11-07 |
| JP2008086319A (ja) | 2008-04-17 |
| RU2227743C2 (ru) | 2004-04-27 |
| CN1340102A (zh) | 2002-03-13 |
| AU762387B2 (en) | 2003-06-26 |
| US7253254B1 (en) | 2007-08-07 |
| WO2000047736A1 (de) | 2000-08-17 |
| DE50015938D1 (de) | 2010-07-22 |
| CN1169959C (zh) | 2004-10-06 |
| ATE470713T1 (de) | 2010-06-15 |
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Effective date: 20140128 |