CA2356696C - Statistical combining of cell expression profiles - Google Patents

Statistical combining of cell expression profiles Download PDF

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Publication number
CA2356696C
CA2356696C CA2356696A CA2356696A CA2356696C CA 2356696 C CA2356696 C CA 2356696C CA 2356696 A CA2356696 A CA 2356696A CA 2356696 A CA2356696 A CA 2356696A CA 2356696 C CA2356696 C CA 2356696C
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Prior art keywords
fluorophore
microarray
pool
genetic matter
labeled
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Expired - Fee Related
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CA2356696A
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English (en)
French (fr)
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CA2356696A1 (en
Inventor
Roland Stoughton
Hongyue Dai
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Microsoft Corp
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Microsoft Corp
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Complex Calculations (AREA)
CA2356696A 1998-12-28 1999-12-27 Statistical combining of cell expression profiles Expired - Fee Related CA2356696C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/222,596 1998-12-28
US09/222,596 US6351712B1 (en) 1998-12-28 1998-12-28 Statistical combining of cell expression profiles
PCT/US1999/030837 WO2000039339A1 (en) 1998-12-28 1999-12-27 Statistical combining of cell expression profiles

Publications (2)

Publication Number Publication Date
CA2356696A1 CA2356696A1 (en) 2000-07-06
CA2356696C true CA2356696C (en) 2011-08-02

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Family Applications (1)

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CA2356696A Expired - Fee Related CA2356696C (en) 1998-12-28 1999-12-27 Statistical combining of cell expression profiles

Country Status (7)

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US (6) US6351712B1 (enExample)
EP (1) EP1141411A4 (enExample)
JP (1) JP2002533701A (enExample)
CN (1) CN1335893A (enExample)
AU (1) AU774830B2 (enExample)
CA (1) CA2356696C (enExample)
WO (1) WO2000039339A1 (enExample)

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Publication number Publication date
US7565251B2 (en) 2009-07-21
US7966130B2 (en) 2011-06-21
US20030093227A1 (en) 2003-05-15
US20050130215A1 (en) 2005-06-16
EP1141411A4 (en) 2007-05-02
US20020128781A1 (en) 2002-09-12
AU2385500A (en) 2000-07-31
US20050164273A1 (en) 2005-07-28
WO2000039339A1 (en) 2000-07-06
US20060190191A1 (en) 2006-08-24
AU774830B2 (en) 2004-07-08
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CA2356696A1 (en) 2000-07-06
US8521441B2 (en) 2013-08-27
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