CA2345767A1 - Therapy for improving cognition - Google Patents

Therapy for improving cognition Download PDF

Info

Publication number
CA2345767A1
CA2345767A1 CA002345767A CA2345767A CA2345767A1 CA 2345767 A1 CA2345767 A1 CA 2345767A1 CA 002345767 A CA002345767 A CA 002345767A CA 2345767 A CA2345767 A CA 2345767A CA 2345767 A1 CA2345767 A1 CA 2345767A1
Authority
CA
Canada
Prior art keywords
atypical antipsychotic
patients suffering
acetylcholinesterase inhibitor
alzheimer
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002345767A
Other languages
English (en)
French (fr)
Inventor
Paul Leonce Irma De Nijs
Wim Louis Julien Parys
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2345767A1 publication Critical patent/CA2345767A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
CA002345767A 1998-10-16 1999-10-12 Therapy for improving cognition Abandoned CA2345767A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98203454.8 1998-10-16
EP98203454 1998-10-16
PCT/EP1999/007804 WO2000023057A2 (en) 1998-10-16 1999-10-12 Atypical antiphsychotic in combination with acetylcholinesterase inhibitor for improving cognition

Publications (1)

Publication Number Publication Date
CA2345767A1 true CA2345767A1 (en) 2000-04-27

Family

ID=8234219

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002345767A Abandoned CA2345767A1 (en) 1998-10-16 1999-10-12 Therapy for improving cognition

Country Status (20)

Country Link
EP (1) EP1121131A2 (pt)
JP (1) JP2002527469A (pt)
KR (1) KR20010072878A (pt)
CN (1) CN1367697A (pt)
AU (1) AU6472799A (pt)
BG (1) BG105302A (pt)
BR (1) BR9914419A (pt)
CA (1) CA2345767A1 (pt)
EE (1) EE200100136A (pt)
HK (1) HK1039745A1 (pt)
HR (1) HRP20010262A2 (pt)
HU (1) HUP0103781A3 (pt)
ID (1) ID28441A (pt)
IL (1) IL142588A0 (pt)
NO (1) NO20011403D0 (pt)
PL (1) PL348107A1 (pt)
SK (1) SK4592001A3 (pt)
TR (1) TR200101082T2 (pt)
WO (1) WO2000023057A2 (pt)
ZA (1) ZA200103081B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0102841D0 (en) * 2001-02-05 2001-03-21 Novartis Ag Organic compounds
AU2006201188B2 (en) * 2001-02-05 2007-11-15 Novartis Ag New use of iloperidone
EP1441727B1 (en) 2001-10-30 2010-12-29 Novartis AG Depot formulations of iloperidone and a star polymer
GB0216416D0 (en) 2002-07-15 2002-08-21 Novartis Ag Organic compounds
WO2004084905A2 (en) * 2003-03-24 2004-10-07 University Of Florida Use of 5-ht2c receptor activity affecting compounds for treating idiopathic hyperhidrosis and associated conditions
TW200501962A (en) * 2003-04-01 2005-01-16 Novartis Ag Use of carbamazepine derivatives for the treatment of agitation in dementia patients
US20050232990A1 (en) * 2003-12-31 2005-10-20 Garth Boehm Donepezil formulations
JP2008523058A (ja) * 2004-12-10 2008-07-03 アボット・ラボラトリーズ 縮合ビシクロ複素環置換キヌクリジン誘導体
WO2008055945A1 (en) 2006-11-09 2008-05-15 Probiodrug Ag 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases
WO2008065141A1 (en) 2006-11-30 2008-06-05 Probiodrug Ag Novel inhibitors of glutaminyl cyclase
ZA200905537B (en) 2007-03-01 2010-10-27 Probiodrug Ag New use of glutaminyl cyclase inhibitors
JP5667440B2 (ja) 2007-04-18 2015-02-12 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体
MX2007008642A (es) * 2007-07-16 2009-02-25 World Trade Imp Export Wtie Ag Composicion farmaceutica que comprende la combinacion de un agente derivado benzisoxazolico y un agente inhibidor reversible de la enzima colinesterasa, indicada para el control y tratamiento de trastornos psicoticos y demencias.
CA2789014C (en) 2010-02-09 2019-01-15 Michela Gallagher Methods and compositions for improving cognitive function
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
MX2012010470A (es) 2010-03-10 2012-10-09 Probiodrug Ag Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5).
US8541596B2 (en) 2010-04-21 2013-09-24 Probiodrug Ag Inhibitors
WO2012123563A1 (en) 2011-03-16 2012-09-20 Probiodrug Ag Benz imidazole derivatives as inhibitors of glutaminyl cyclase
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
WO2016191288A1 (en) 2015-05-22 2016-12-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
EP3461819B1 (en) 2017-09-29 2020-05-27 Probiodrug AG Inhibitors of glutaminyl cyclase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69229781T2 (de) * 1991-05-14 2000-01-05 Ernir Snorrason Behandlung des ermüdungssyndroms mit cholinesteraseinhibitoren
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
DK1011678T3 (da) * 1997-08-11 2008-05-05 Univ South Florida Anvendelse af mecamylamin til behandling af nikotin-responsive neuropsykiatriske lidelser
ATE369848T1 (de) * 1998-04-14 2007-09-15 Gen Hospital Corp Verwendung von d-serine oder d-alanine zur behandlung von schizophrenie

Also Published As

Publication number Publication date
NO20011403L (no) 2001-03-20
WO2000023057A3 (en) 2000-07-27
HRP20010262A2 (en) 2002-06-30
NO20011403D0 (no) 2001-03-20
CN1367697A (zh) 2002-09-04
IL142588A0 (en) 2002-03-10
EP1121131A2 (en) 2001-08-08
WO2000023057A2 (en) 2000-04-27
SK4592001A3 (en) 2001-12-03
TR200101082T2 (tr) 2001-09-21
PL348107A1 (en) 2002-05-06
KR20010072878A (ko) 2001-07-31
HK1039745A1 (zh) 2002-05-10
ZA200103081B (en) 2002-07-12
ID28441A (id) 2001-05-24
EE200100136A (et) 2002-06-17
BG105302A (en) 2001-11-30
AU6472799A (en) 2000-05-08
HUP0103781A3 (en) 2003-09-29
HUP0103781A2 (hu) 2002-03-28
BR9914419A (pt) 2001-06-26
JP2002527469A (ja) 2002-08-27

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Legal Events

Date Code Title Description
FZDE Discontinued