CA2345638A1 - Formes posologiques a administration par voie orale contenant le compose (2s,3s,5r)-2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol et une quantite stabilisante efficace d'acide alginique - Google Patents
Formes posologiques a administration par voie orale contenant le compose (2s,3s,5r)-2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol et une quantite stabilisante efficace d'acide alginique Download PDFInfo
- Publication number
- CA2345638A1 CA2345638A1 CA002345638A CA2345638A CA2345638A1 CA 2345638 A1 CA2345638 A1 CA 2345638A1 CA 002345638 A CA002345638 A CA 002345638A CA 2345638 A CA2345638 A CA 2345638A CA 2345638 A1 CA2345638 A1 CA 2345638A1
- Authority
- CA
- Canada
- Prior art keywords
- oral dosage
- dosage form
- discrete oral
- discrete
- alginic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne des formes posologiques discrètes à administration par voie orale, généralement des comprimés ou des gélules, contenant le composé (2S,3S,5R)-2-(3,5-difluorophényl)-3,5-diméthyl-2-morpholinol ou un sel ou solvate physiologiquement acceptable de ce composé, ou un solvate dudit sel, et une quantité stabilisante efficace d'acide alginique. Ces formes posologiques sont utiles pour prévenir ou traiter l'hypercinésie avec déficit de l'attention ou la dépression, ou pour traiter l'accoutumance à des produits contenant de la nicotine, en particulier des produits contenant du tabac, afin d'aider, par exemple, un patient à s'arrêter de fumer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10211298P | 1998-09-28 | 1998-09-28 | |
US60/102,112 | 1998-09-28 | ||
PCT/EP1999/007117 WO2000018406A1 (fr) | 1998-09-28 | 1999-09-24 | Formes posologiques a administration par voie orale contenant le compose (2s,3s,5r)-2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol et une quantite stabilisante efficace d'acide alginique |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2345638A1 true CA2345638A1 (fr) | 2000-04-06 |
Family
ID=22288187
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002345638A Abandoned CA2345638A1 (fr) | 1998-09-28 | 1999-09-24 | Formes posologiques a administration par voie orale contenant le compose (2s,3s,5r)-2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol et une quantite stabilisante efficace d'acide alginique |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1117407A1 (fr) |
JP (1) | JP2002525328A (fr) |
KR (1) | KR20010075385A (fr) |
CN (1) | CN1328459A (fr) |
AR (1) | AR022673A1 (fr) |
AU (1) | AU6087399A (fr) |
BR (1) | BR9914096A (fr) |
CA (1) | CA2345638A1 (fr) |
CZ (1) | CZ20011142A3 (fr) |
HU (1) | HUP0103459A2 (fr) |
IL (1) | IL142054A0 (fr) |
MA (1) | MA26693A1 (fr) |
NO (1) | NO20011555D0 (fr) |
PE (1) | PE20001087A1 (fr) |
PL (1) | PL346877A1 (fr) |
TR (1) | TR200100863T2 (fr) |
WO (1) | WO2000018406A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1220673A2 (fr) * | 1999-10-13 | 2002-07-10 | Glaxo Group Limited | Methode destinee au traitement de l'obesite |
DE102008047910A1 (de) | 2008-09-19 | 2010-03-25 | Molkerei Meggle Wasserburg Gmbh & Co. Kg | Tablettierhilfsstoff auf Laktose- und Cellulosebasis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4597969A (en) * | 1982-04-05 | 1986-07-01 | Merck Sharp & Dohme | Stabilization of unstable drugs or food supplements |
GB8924528D0 (en) * | 1989-10-31 | 1989-12-20 | Wellcome Found | Heterocyclic pharmaceutical compounds,preparation and use |
-
1999
- 1999-09-23 MA MA25782A patent/MA26693A1/fr unknown
- 1999-09-24 CZ CZ20011142A patent/CZ20011142A3/cs unknown
- 1999-09-24 HU HU0103459A patent/HUP0103459A2/hu unknown
- 1999-09-24 BR BR9914096-9A patent/BR9914096A/pt not_active IP Right Cessation
- 1999-09-24 PL PL99346877A patent/PL346877A1/xx unknown
- 1999-09-24 CN CN99813675A patent/CN1328459A/zh active Pending
- 1999-09-24 TR TR2001/00863T patent/TR200100863T2/xx unknown
- 1999-09-24 KR KR1020017003874A patent/KR20010075385A/ko not_active Application Discontinuation
- 1999-09-24 WO PCT/EP1999/007117 patent/WO2000018406A1/fr not_active Application Discontinuation
- 1999-09-24 CA CA002345638A patent/CA2345638A1/fr not_active Abandoned
- 1999-09-24 AU AU60873/99A patent/AU6087399A/en not_active Abandoned
- 1999-09-24 EP EP99947420A patent/EP1117407A1/fr not_active Withdrawn
- 1999-09-24 JP JP2000571924A patent/JP2002525328A/ja active Pending
- 1999-09-24 AR ARP990104841A patent/AR022673A1/es unknown
- 1999-09-24 IL IL14205499A patent/IL142054A0/xx unknown
- 1999-09-27 PE PE1999000976A patent/PE20001087A1/es not_active Application Discontinuation
-
2001
- 2001-03-27 NO NO20011555A patent/NO20011555D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PL346877A1 (en) | 2002-03-11 |
TR200100863T2 (tr) | 2001-07-23 |
AR022673A1 (es) | 2002-09-04 |
BR9914096A (pt) | 2001-07-31 |
CZ20011142A3 (cs) | 2001-09-12 |
JP2002525328A (ja) | 2002-08-13 |
WO2000018406A1 (fr) | 2000-04-06 |
HUP0103459A2 (hu) | 2002-01-28 |
NO20011555L (no) | 2001-03-27 |
PE20001087A1 (es) | 2000-10-20 |
EP1117407A1 (fr) | 2001-07-25 |
AU6087399A (en) | 2000-04-17 |
IL142054A0 (en) | 2002-03-10 |
MA26693A1 (fr) | 2004-12-20 |
KR20010075385A (ko) | 2001-08-09 |
NO20011555D0 (no) | 2001-03-27 |
CN1328459A (zh) | 2001-12-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |