TR200100863T2 - (2S,3S,5R)-2-(3,5-Diflorofenil)-3,5-dimetil-2-morfolinol ve etkili dengeleyici miktarda alginik asit içeren oral dozaj formülasyonları. - Google Patents

(2S,3S,5R)-2-(3,5-Diflorofenil)-3,5-dimetil-2-morfolinol ve etkili dengeleyici miktarda alginik asit içeren oral dozaj formülasyonları.

Info

Publication number
TR200100863T2
TR200100863T2 TR2001/00863T TR200100863T TR200100863T2 TR 200100863 T2 TR200100863 T2 TR 200100863T2 TR 2001/00863 T TR2001/00863 T TR 2001/00863T TR 200100863 T TR200100863 T TR 200100863T TR 200100863 T2 TR200100863 T2 TR 200100863T2
Authority
TR
Turkey
Prior art keywords
morpholinol
difluorophenyl
dimethyl
alginic acid
oral dosage
Prior art date
Application number
TR2001/00863T
Other languages
English (en)
Inventor
Bruce Balik Samuel
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of TR200100863T2 publication Critical patent/TR200100863T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Bu bulus (2S, 3S, 5R)-2-(3,5-diflorofenil)-3,5-dimetil-2-morfolinol veya bunun fizyolojik olarak uygun bir tuzunu veya çözünmüs halini, veya bahsedilen tuzun bir çözünmüs halini ve alginik asidin etkili dayaniklilik saglayici bir miktarini içeren tipik olarak tabletler veya kapsüller olan ayri oral dozaj formlari saglar. Bu dozaj formlari dikkat eksikligi hiperkinezi bozuklugu veya depresyonun önlenmesi veya tedavi edilmesinde, nikotin içeren ürünlere bagimliligin tedavisinde, örnegin sigaranin birakilmasina yardimci olmasi için, özellikle tütün içeren ürünlere bagimliligin tedavi edilmesinde yararlidir.
TR2001/00863T 1998-09-28 1999-09-24 (2S,3S,5R)-2-(3,5-Diflorofenil)-3,5-dimetil-2-morfolinol ve etkili dengeleyici miktarda alginik asit içeren oral dozaj formülasyonları. TR200100863T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10211298P 1998-09-28 1998-09-28

Publications (1)

Publication Number Publication Date
TR200100863T2 true TR200100863T2 (tr) 2001-07-23

Family

ID=22288187

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00863T TR200100863T2 (tr) 1998-09-28 1999-09-24 (2S,3S,5R)-2-(3,5-Diflorofenil)-3,5-dimetil-2-morfolinol ve etkili dengeleyici miktarda alginik asit içeren oral dozaj formülasyonları.

Country Status (17)

Country Link
EP (1) EP1117407A1 (tr)
JP (1) JP2002525328A (tr)
KR (1) KR20010075385A (tr)
CN (1) CN1328459A (tr)
AR (1) AR022673A1 (tr)
AU (1) AU6087399A (tr)
BR (1) BR9914096A (tr)
CA (1) CA2345638A1 (tr)
CZ (1) CZ20011142A3 (tr)
HU (1) HUP0103459A2 (tr)
IL (1) IL142054A0 (tr)
MA (1) MA26693A1 (tr)
NO (1) NO20011555D0 (tr)
PE (1) PE20001087A1 (tr)
PL (1) PL346877A1 (tr)
TR (1) TR200100863T2 (tr)
WO (1) WO2000018406A1 (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1220673A2 (en) * 1999-10-13 2002-07-10 Glaxo Group Limited Morpholinol derivatives for the treatment of obesity
DE102008047910A1 (de) 2008-09-19 2010-03-25 Molkerei Meggle Wasserburg Gmbh & Co. Kg Tablettierhilfsstoff auf Laktose- und Cellulosebasis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4597969A (en) * 1982-04-05 1986-07-01 Merck Sharp & Dohme Stabilization of unstable drugs or food supplements
GB8924528D0 (en) * 1989-10-31 1989-12-20 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use

Also Published As

Publication number Publication date
PL346877A1 (en) 2002-03-11
CA2345638A1 (en) 2000-04-06
AR022673A1 (es) 2002-09-04
BR9914096A (pt) 2001-07-31
CZ20011142A3 (cs) 2001-09-12
JP2002525328A (ja) 2002-08-13
WO2000018406A1 (en) 2000-04-06
HUP0103459A2 (hu) 2002-01-28
NO20011555L (no) 2001-03-27
PE20001087A1 (es) 2000-10-20
EP1117407A1 (en) 2001-07-25
AU6087399A (en) 2000-04-17
IL142054A0 (en) 2002-03-10
MA26693A1 (fr) 2004-12-20
KR20010075385A (ko) 2001-08-09
NO20011555D0 (no) 2001-03-27
CN1328459A (zh) 2001-12-26

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