CA2329160A1 - Traitement des blessures par inhibition d'adenosine diphosphate-ribosyl transferase - Google Patents

Traitement des blessures par inhibition d'adenosine diphosphate-ribosyl transferase Download PDF

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Publication number
CA2329160A1
CA2329160A1 CA002329160A CA2329160A CA2329160A1 CA 2329160 A1 CA2329160 A1 CA 2329160A1 CA 002329160 A CA002329160 A CA 002329160A CA 2329160 A CA2329160 A CA 2329160A CA 2329160 A1 CA2329160 A1 CA 2329160A1
Authority
CA
Canada
Prior art keywords
vitamin
wound healing
vegf
adenosine diphosphate
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002329160A
Other languages
English (en)
Inventor
Samuel J. Leibovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Medicine and Dentistry of New Jersey
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2329160A1 publication Critical patent/CA2329160A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

L'invention concerne une méthode permettant de soigner une blessure chez un mammifère. Cette méthode consiste à utiliser une composition thérapeutique de régénération des blessures comprenant une quantité efficace du point de vue thérapeutique d'un inhibiteur de mono-adénosine diphosphate-ribosyl transférase, de manière à inhiber l'adénosine diphosphate-ribosylation du facteur de croissance de l'endothélium vasculaire. Cette méthode consiste également à mettre en contact la composition thérapeutique de régénération des blessures avec une blessure d'un mammifère. L'invention concerne également des compositions de régénération des blessures ainsi que des méthodes de préparation et d'utilisation de ces compositions et des produits pharmaceutiques dans lesquels ces compositions peuvent être utilisées. L'invention concerne en outre des compositions thérapeutiques de régénération des blessures cutanées utiles pour traiter et atténuer les effets de l'érythème fessier du nourrisson ainsi que des méthodes de préparation et d'utilisation de ces compositions.
CA002329160A 1998-06-11 1999-06-11 Traitement des blessures par inhibition d'adenosine diphosphate-ribosyl transferase Abandoned CA2329160A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8892498P 1998-06-11 1998-06-11
US60/088,924 1998-06-11
PCT/US1999/013264 WO1999063982A1 (fr) 1998-06-11 1999-06-11 Traitement des blessures par inhibition d'adenosine diphosphate-ribosyl transferase

Publications (1)

Publication Number Publication Date
CA2329160A1 true CA2329160A1 (fr) 1999-12-16

Family

ID=22214311

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002329160A Abandoned CA2329160A1 (fr) 1998-06-11 1999-06-11 Traitement des blessures par inhibition d'adenosine diphosphate-ribosyl transferase

Country Status (5)

Country Link
EP (1) EP1085859A4 (fr)
JP (1) JP2002517436A (fr)
AU (1) AU4438399A (fr)
CA (1) CA2329160A1 (fr)
WO (1) WO1999063982A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2401340A1 (fr) * 2000-02-28 2001-09-07 The University Of British Columbia Compositions et methodes de traitement de maladies inflammatoires en utilisant des inhibiteurs de topoisomerase
US6538030B2 (en) * 2000-09-20 2003-03-25 Yih-Lin Chung Treating radiation fibrosis
DE10225772A1 (de) * 2002-06-10 2003-12-24 Beiersdorf Ag Kosmetische oder dermatologische Formulierungen zur Pflege der Haut nach einem Sonnenbad oder einer Rasur
US7105336B2 (en) * 2002-10-07 2006-09-12 Biogaia Ab Selection and use of lactic acid bacteria for reducing inflammation caused by Helicobacter
US7893244B2 (en) 2005-04-12 2011-02-22 Intradigm Corporation Composition and methods of RNAi therapeutics for treatment of cancer and other neovascularization diseases
BRPI0610499A2 (pt) 2005-04-12 2010-06-22 Intradigm Corp moléculas de ácido nucléico , composições e usos das referidas moléculas
EP2494965A3 (fr) * 2005-04-15 2013-01-02 The Albert Einstein College Of Medicine Of Yeshiva University Vitamine K pour la prévention et le traitement des éruptions cutanées suite à une thérapie anti-egfr
FR2885802A1 (fr) * 2005-05-17 2006-11-24 Oreal Utilisation cosmetique de la vitamine k pour ameliorer la fonction barriere de la peau
US8815953B2 (en) 2008-03-13 2014-08-26 Spectrum Pharmaceuticals, Inc. Formulations of vitamin K analogs for topical use
EP2712613B1 (fr) * 2012-09-28 2017-02-08 Pharmadab d.o.o. Vitamine K1 et ses utilisations
TWI578994B (zh) * 2014-03-27 2017-04-21 中央研究院 燒燙傷口癒合組合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2074627A1 (en) * 1970-01-13 1971-10-08 Socres Ppsoriasis treatment compsn
US4029770A (en) * 1974-03-26 1977-06-14 Caw Industries, Inc. Method of therapeutically treating damaged and/or infected tissue and relieving stress and shock in warm blooded animals
US4289757A (en) * 1978-02-28 1981-09-15 The Upjohn Company Method for treating inflammation
US5602183A (en) * 1991-03-01 1997-02-11 Warner-Lambert Company Dermatological wound healing compositions and methods for preparing and using same
IT1253431B (it) * 1991-12-02 1995-08-08 Valetudo S R L Preparati farmaceutici per uso topico destinati al trattamento della psoriasi e della dermatite atopica
IT1265340B1 (it) * 1993-07-14 1996-11-22 Istituto Biochimico Italiano Sostanze inibenti l'adp-ribosilazione proteica atte alla prevenzione delle complicanze del diabete mellito.
US5677349A (en) * 1995-04-27 1997-10-14 Gilad; Gad M. Agmatine for the treatment of neurotrauma and neurodegenerative diseases
AU2804297A (en) * 1996-04-22 1997-11-12 Advanced Polymer Systems Inc. Method of and composition for treating disorders of the skin using vitamin k
CN1133417C (zh) * 1996-04-23 2004-01-07 普罗克特和甘保尔公司 维生素b3化合物调节皮肤外观的方法

Also Published As

Publication number Publication date
AU4438399A (en) 1999-12-30
JP2002517436A (ja) 2002-06-18
WO1999063982A1 (fr) 1999-12-16
EP1085859A1 (fr) 2001-03-28
EP1085859A4 (fr) 2003-02-26

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Legal Events

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EEER Examination request
FZDE Dead