CA2325765A1 - Methodes de production et d'administration de preparations combinant un antagoniste de rho et un adhesif tissulaire aux systemes nerveux central et peripherique leses de mammiferes et utilisations de ces preparations - Google Patents

Methodes de production et d'administration de preparations combinant un antagoniste de rho et un adhesif tissulaire aux systemes nerveux central et peripherique leses de mammiferes et utilisations de ces preparations Download PDF

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Publication number
CA2325765A1
CA2325765A1 CA002325765A CA2325765A CA2325765A1 CA 2325765 A1 CA2325765 A1 CA 2325765A1 CA 002325765 A CA002325765 A CA 002325765A CA 2325765 A CA2325765 A CA 2325765A CA 2325765 A1 CA2325765 A1 CA 2325765A1
Authority
CA
Canada
Prior art keywords
rho
fibrin
matrix
antagonist
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002325765A
Other languages
English (en)
Inventor
Lisa Mckerracher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002325765A priority Critical patent/CA2325765A1/fr
Priority to CA002325842A priority patent/CA2325842C/fr
Priority to US09/725,906 priority patent/US7141428B2/en
Publication of CA2325765A1 publication Critical patent/CA2325765A1/fr
Priority to US10/718,598 priority patent/US7491692B2/en
Priority to US12/175,268 priority patent/US20090136573A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002325765A 2000-11-02 2000-11-02 Methodes de production et d'administration de preparations combinant un antagoniste de rho et un adhesif tissulaire aux systemes nerveux central et peripherique leses de mammiferes et utilisations de ces preparations Abandoned CA2325765A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002325765A CA2325765A1 (fr) 2000-11-02 2000-11-02 Methodes de production et d'administration de preparations combinant un antagoniste de rho et un adhesif tissulaire aux systemes nerveux central et peripherique leses de mammiferes et utilisations de ces preparations
CA002325842A CA2325842C (fr) 2000-11-02 2000-11-29 Methodes de production et d'administration de preparations combinant un antagoniste de rho et un adhesif tissulaire aux systemes nerveux central et peripherique blesses de mammiferes et utilisations de ces preparations
US09/725,906 US7141428B2 (en) 2000-11-02 2000-11-30 Methods for making and delivering rho-antagonist tissue adhesive formulations to the injured mammalian central and peripheral nervous systems and uses thereof
US10/718,598 US7491692B2 (en) 2000-11-02 2003-11-24 Methods for making and delivering Rho-antagonist tissue adhesive formulations to the injured mammalian central and peripheral nervous systems and uses thereof
US12/175,268 US20090136573A1 (en) 2000-11-02 2008-07-17 Methods for Making and Delivering Rho-Antagonist Tissue Adhesive Formulations to the Injured Mammalian Central and Peripheral Nervous Systems and uses Thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002325765A CA2325765A1 (fr) 2000-11-02 2000-11-02 Methodes de production et d'administration de preparations combinant un antagoniste de rho et un adhesif tissulaire aux systemes nerveux central et peripherique leses de mammiferes et utilisations de ces preparations

Publications (1)

Publication Number Publication Date
CA2325765A1 true CA2325765A1 (fr) 2002-05-02

Family

ID=4167627

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002325765A Abandoned CA2325765A1 (fr) 2000-11-02 2000-11-02 Methodes de production et d'administration de preparations combinant un antagoniste de rho et un adhesif tissulaire aux systemes nerveux central et peripherique leses de mammiferes et utilisations de ces preparations

Country Status (1)

Country Link
CA (1) CA2325765A1 (fr)

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