CA2319640C - Electrochemically reactive cathodes for an electrotransport device - Google Patents

Electrochemically reactive cathodes for an electrotransport device Download PDF

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Publication number
CA2319640C
CA2319640C CA002319640A CA2319640A CA2319640C CA 2319640 C CA2319640 C CA 2319640C CA 002319640 A CA002319640 A CA 002319640A CA 2319640 A CA2319640 A CA 2319640A CA 2319640 C CA2319640 C CA 2319640C
Authority
CA
Canada
Prior art keywords
electrode
cathodic
silver halide
body surface
electrolyte reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002319640A
Other languages
English (en)
French (fr)
Other versions
CA2319640A1 (en
Inventor
Lothar W. Kleiner
Erik R. Scott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of CA2319640A1 publication Critical patent/CA2319640A1/en
Application granted granted Critical
Publication of CA2319640C publication Critical patent/CA2319640C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/4998—Combined manufacture including applying or shaping of fluent material
    • Y10T29/49988—Metal casting
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/4998—Combined manufacture including applying or shaping of fluent material
    • Y10T29/49988—Metal casting
    • Y10T29/49991—Combined with rolling

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Discharge Lamp (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Medicinal Preparation (AREA)
CA002319640A 1998-01-28 1999-01-28 Electrochemically reactive cathodes for an electrotransport device Expired - Fee Related CA2319640C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7280698P 1998-01-28 1998-01-28
US7282398P 1998-01-28 1998-01-28
US60/072,806 1998-01-28
US60/072,823 1998-01-28
PCT/US1999/001748 WO1999038564A1 (en) 1998-01-28 1999-01-28 Electrochemically reactive cathodes for an electrotransport device

Publications (2)

Publication Number Publication Date
CA2319640A1 CA2319640A1 (en) 1999-08-05
CA2319640C true CA2319640C (en) 2010-01-19

Family

ID=26753770

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002319640A Expired - Fee Related CA2319640C (en) 1998-01-28 1999-01-28 Electrochemically reactive cathodes for an electrotransport device

Country Status (12)

Country Link
US (1) US6505069B2 (US07585860-20090908-C00162.png)
EP (1) EP1051219B1 (US07585860-20090908-C00162.png)
JP (1) JP4221151B2 (US07585860-20090908-C00162.png)
KR (1) KR100550492B1 (US07585860-20090908-C00162.png)
CN (1) CN1147330C (US07585860-20090908-C00162.png)
AT (1) ATE274973T1 (US07585860-20090908-C00162.png)
AU (1) AU2346499A (US07585860-20090908-C00162.png)
CA (1) CA2319640C (US07585860-20090908-C00162.png)
DE (1) DE69919841T2 (US07585860-20090908-C00162.png)
DK (1) DK1051219T3 (US07585860-20090908-C00162.png)
ES (1) ES2229672T3 (US07585860-20090908-C00162.png)
WO (1) WO1999038564A1 (US07585860-20090908-C00162.png)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
KR100822339B1 (ko) * 2000-09-11 2008-04-16 알자 코포레이션 경피 전기운반 장치 및 그 제조 방법
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US7349733B2 (en) * 2001-11-02 2008-03-25 Ceramatel, Inc. Iontophoretic drug delivery systems
DE10205373B4 (de) * 2002-02-09 2007-07-19 Aloys Wobben Brandschutz
US7018345B2 (en) * 2002-12-06 2006-03-28 Hisamitsu Pharmaceutical Co., Inc. Iontophoresis system
US7340310B2 (en) * 2004-06-28 2008-03-04 Power Paper, Ltd. Multi-layered electrodes and uses thereof
JP4615929B2 (ja) * 2004-08-11 2011-01-19 久光製薬株式会社 イオントフォレーシス装置
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
WO2006055729A1 (en) * 2004-11-16 2006-05-26 Transcutaneous Technologies Inc. Iontophoretic device and method for administering immune response-enhancing agents and compositions
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
JP2007037868A (ja) * 2005-08-05 2007-02-15 Transcutaneous Technologies Inc 経皮投与装置及びその制御方法
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070060860A1 (en) * 2005-08-18 2007-03-15 Transcutaneous Technologies Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
US20090254018A1 (en) * 2005-08-24 2009-10-08 Mizuo Nakayama Electrode assembly for freezing-type iontophoresis device
US20100016781A1 (en) * 2005-08-29 2010-01-21 Mizuo Nakayama Iontophoresis device selecting drug to be administered on the basis of information form sensor
JPWO2007026672A1 (ja) * 2005-08-29 2009-03-05 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス用汎用性電解液組成物
WO2007029611A1 (ja) * 2005-09-06 2007-03-15 Tti Ellebeau, Inc. イオントフォレーシス装置
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
WO2007032446A1 (ja) 2005-09-15 2007-03-22 Tti Ellebeau, Inc. ロッド型イオントフォレーシス装置
BRPI0616166A2 (pt) * 2005-09-16 2011-06-07 Tti Ellebeau Inc dispositivo de iontoforese do tipo de cateter
US20090299264A1 (en) * 2005-09-28 2009-12-03 Tti Ellebeau, Inc. Electrode Assembly for Dry Type Iontophoresis
EP1931417A2 (en) * 2005-09-30 2008-06-18 Transcutaneous Technologies Inc. Transdermal drug delivery systems, devices, and methods employing novel pharmaceutical vehicles
US20070232983A1 (en) * 2005-09-30 2007-10-04 Smith Gregory A Handheld apparatus to deliver active agents to biological interfaces
JP2009509677A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 小胞封入活性物質のイオントフォレーシス送達
EP1928539A1 (en) * 2005-09-30 2008-06-11 Tti Ellebeau, Inc. Functionalized microneedles transdermal drug delivery systems, devices, and methods
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
JPWO2007037476A1 (ja) * 2005-09-30 2009-04-16 Ｔｔｉ・エルビュー株式会社 睡眠導入剤と興奮剤の投与量および投与時期を制御するイオントフォレーシス装置
US20070093787A1 (en) * 2005-09-30 2007-04-26 Transcutaneous Technologies Inc. Iontophoresis device to deliver multiple active agents to biological interfaces
WO2007037475A1 (ja) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置
JP2009509656A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 生体界面に活性物質を送達するイオントフォレーシス装置における動作不良を検出するための方法及びシステム
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
JP4804904B2 (ja) * 2005-12-09 2011-11-02 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置包装品
WO2007079116A1 (en) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
US20080033398A1 (en) * 2005-12-29 2008-02-07 Transcutaneous Technologies Inc. Device and method for enhancing immune response by electrical stimulation
MX2009002321A (es) * 2006-09-05 2009-03-23 Tti Ellebeau Inc Sistemas, dispositivos y metodos de suministro transdermico de farmacos que utilizan suministros de energia inductiva.
KR20090106492A (ko) 2006-12-01 2009-10-09 티티아이 엘뷰 가부시키가이샤 경피성 전달 장치와 같은 장치에 전력을 제공하거나 제어하기 위한 시스템, 장치, 및 방법
US20080177219A1 (en) * 2007-01-23 2008-07-24 Joshi Ashok V Method for Iontophoretic Fluid Delivery
US20080214985A1 (en) * 2007-02-02 2008-09-04 Activatek, Inc. Active transdermal medicament patch
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US20100312168A1 (en) * 2009-06-09 2010-12-09 Yoshimasa Yoshida Long life high capacity electrode, device, and method of manufacture
AU2010286917B2 (en) * 2009-08-31 2016-03-10 Abbott Diabetes Care Inc. Medical devices and methods
US9125625B2 (en) 2010-06-10 2015-09-08 The Regents Of The University Of California Textile-based printable electrodes for electrochemical sensing
US9159945B2 (en) * 2012-12-13 2015-10-13 Universal Display Corporation System and method for matching electrode resistances in OLED light panels
US10898116B2 (en) * 2013-03-15 2021-01-26 Cambridge Medical Technologies LLC Methods of manufacture to optimize performance of transdermal sampling and analysis device
WO2016090189A1 (en) * 2014-12-03 2016-06-09 The Regents Of The University Of California Non-invasive and wearable chemical sensors and biosensors
US11045142B1 (en) 2017-04-29 2021-06-29 Biolinq, Inc. Heterogeneous integration of silicon-fabricated solid microneedle sensors and CMOS circuitry
US11633129B2 (en) 2019-04-05 2023-04-25 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating redox cofactors
US11375931B2 (en) 2019-08-08 2022-07-05 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating an electrochemical bioassay
JP7319742B2 (ja) 2020-07-29 2023-08-02 バイオリンク インコーポレイテッド 微小針アレイを伴う持続的分析物監視システム
SE2330048A1 (en) 2021-05-08 2023-01-25 Biolinq Incorporated Fault detection for microneedle array based continuous analyte monitoring device

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110130A (en) * 1976-09-29 1978-08-29 Scm Corporation Forging powdered dispersion strengthened metal
US4383529A (en) 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
JPS58197206A (ja) * 1982-04-30 1983-11-16 Hitachi Metals Ltd 高品位金属または合金粉末の製造方法
US5135477A (en) 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4747819A (en) 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4847980A (en) * 1987-11-16 1989-07-18 The Governors Of The University Of Alberta Method of manufacturing transmural cardiac electrodes
US5320597A (en) 1991-02-08 1994-06-14 Becton, Dickinson And Company Device and method for renewing electrodes during iontophoresis
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US5147297A (en) 1990-05-07 1992-09-15 Alza Corporation Iontophoretic delivery device
WO1992015365A1 (en) * 1991-03-11 1992-09-17 Alza Corporation Iontophoretic delivery device and method of making same
US5405317A (en) 1991-05-03 1995-04-11 Alza Corporation Iontophoretic delivery device
US5533971A (en) * 1993-09-03 1996-07-09 Alza Corporation Reduction of skin irritation during electrotransport
US5427736A (en) * 1994-04-05 1995-06-27 General Electric Company Method of making metal alloy foils
AU2682795A (en) * 1994-06-17 1996-01-15 Hisamitsu Pharmaceutical Co., Inc. Electrode for iontophoresis and device using the same
AU3728995A (en) * 1994-09-29 1996-04-19 Becton Dickinson & Company Method of preparing silver chloride electrodes for iontophoretic drug delivery devices
US5911919A (en) * 1997-09-08 1999-06-15 Integrated Thermal Sciences, Inc. Electron emission materials and components
US6190579B1 (en) * 1997-09-08 2001-02-20 Integrated Thermal Sciences, Inc. Electron emission materials and components

Also Published As

Publication number Publication date
WO1999038564A1 (en) 1999-08-05
CN1289260A (zh) 2001-03-28
CA2319640A1 (en) 1999-08-05
US20020055704A1 (en) 2002-05-09
CN1147330C (zh) 2004-04-28
EP1051219B1 (en) 2004-09-01
DE69919841T2 (de) 2005-09-22
JP4221151B2 (ja) 2009-02-12
US6505069B2 (en) 2003-01-07
AU2346499A (en) 1999-08-16
ATE274973T1 (de) 2004-09-15
KR100550492B1 (ko) 2006-02-09
EP1051219A1 (en) 2000-11-15
ES2229672T3 (es) 2005-04-16
KR20010034445A (ko) 2001-04-25
DE69919841D1 (de) 2004-10-07
DK1051219T3 (da) 2005-01-10
JP2002501794A (ja) 2002-01-22

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20130128