CA2304961A1 - Procedes et compositions utilises pour lier des cellules souches hematopoietiques - Google Patents

Procedes et compositions utilises pour lier des cellules souches hematopoietiques Download PDF

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Publication number
CA2304961A1
CA2304961A1 CA002304961A CA2304961A CA2304961A1 CA 2304961 A1 CA2304961 A1 CA 2304961A1 CA 002304961 A CA002304961 A CA 002304961A CA 2304961 A CA2304961 A CA 2304961A CA 2304961 A1 CA2304961 A1 CA 2304961A1
Authority
CA
Canada
Prior art keywords
binding partner
stem cells
lectin
cells
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002304961A
Other languages
English (en)
Inventor
John L. Magnani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlycoTech Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2304961A1 publication Critical patent/CA2304961A1/fr
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

L'invention concerne des procédés et des compositions utilisés pour lier des cellules souches hématopoïétiques. Les procédés de l'invention consistent généralement à utiliser un partenaire de liaison qui forme un complexe avec une structure à base de lactosamine syalylée présente sur la surface des cellules souches. La formation desdits complexes facilite, par exemple, l'immobilisation, la purification, l'identification et le ciblage de cellules souches hématopoïétiques. Lesdites compositions de l'invention comprennent généralement un partenaire de liaison qui peut être libre, fixé à un matériau de support ou lié à un agent marqueur ou thérapeutique.
CA002304961A 1997-09-25 1998-09-24 Procedes et compositions utilises pour lier des cellules souches hematopoietiques Abandoned CA2304961A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5997297P 1997-09-25 1997-09-25
US60/059,972 1997-09-25
PCT/US1998/020063 WO1999015628A1 (fr) 1997-09-25 1998-09-24 Procedes et compositions utilises pour lier des cellules souches hematopoietiques

Publications (1)

Publication Number Publication Date
CA2304961A1 true CA2304961A1 (fr) 1999-04-01

Family

ID=22026508

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002304961A Abandoned CA2304961A1 (fr) 1997-09-25 1998-09-24 Procedes et compositions utilises pour lier des cellules souches hematopoietiques

Country Status (6)

Country Link
EP (1) EP1017790A1 (fr)
JP (1) JP2001517427A (fr)
CN (1) CN1280611A (fr)
AU (1) AU9508998A (fr)
CA (1) CA2304961A1 (fr)
WO (1) WO1999015628A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE307881T1 (de) 1999-03-30 2005-11-15 Netech Inc Methode zur selektiven trennung von blutzellen unter verwendung von lektin
AU2001277635A1 (en) * 2000-03-14 2001-10-08 Exiqon A/S New methods for separation and isolation of subpopulations of cells in biological samples
WO2002040644A1 (fr) * 2000-11-15 2002-05-23 Yukio Kato Agent conferant une resistance a des stimuli exterieurs
AU2004227205B2 (en) * 2003-04-08 2010-06-10 Yeda Research And Development Co. Ltd Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
US8691774B2 (en) 2005-07-11 2014-04-08 Glykos Finland Oy Carbohydrate profile compositions from human cells and methods for analysis and modification thereof
WO2007054620A1 (fr) * 2005-11-08 2007-05-18 Suomen Punainen Risti, Veripalvelu Nouvelles compositions a profils glucidiques tirees de cellules humaines et procedes d'analyse et de modification correspondants
WO2008000918A1 (fr) * 2006-06-29 2008-01-03 Suomen Punainen Risti, Veripalvelu Nouvelles compositions de glycane cellulaire
KR20080037883A (ko) * 2006-10-27 2008-05-02 세원셀론텍(주) 메디컬 키트 및 이의 사용방법
JP2010516239A (ja) * 2007-01-18 2010-05-20 スオメン プナイネン リスティ，ヴェリパルベル 細胞の産生に対する新規方法および試薬
JP2010516240A (ja) * 2007-01-18 2010-05-20 スオメン プナイネン リスティ，ヴェリパルベル ヒト細胞からの新規の炭水化物、ならびにその分析および修飾のための方法
KR101955053B1 (ko) * 2011-06-06 2019-03-06 리제네시스 비브이비에이 중공 섬유 생물 반응기에서의 줄기 세포의 확장
CN203333671U (zh) * 2011-10-28 2013-12-11 卢磊磊 凝集素用于识别、纯化干细胞的试剂盒
CN203333672U (zh) * 2011-10-28 2013-12-11 李福生 从造血器官、血液标本中获得干细胞的细胞处理试剂盒
JP6200949B2 (ja) * 2012-05-31 2017-09-20 エイジェンシー フォー サイエンス，テクノロジー アンド リサーチ 固相ウレイドに対する生物学的標的物の選択的結合
JP6057574B2 (ja) * 2012-07-11 2017-01-11 キヤノン株式会社 造血幹細胞識別用プローブ
EP3371222A1 (fr) * 2015-11-03 2018-09-12 GlycoMimetics, Inc. Procédés et compositions pour la production d'anticorps monoclonaux, cellules souches hématopoïétiques et méthodes d'utilisation de celles-ci
EP3919520B1 (fr) * 2019-02-01 2024-07-10 Sumitomo Chemical Company, Limited Anticorps et fragment fonctionnel de celui-ci

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5227160A (en) * 1988-07-15 1993-07-13 The Biomembrane Institute Monoclonal antibody nuh2 capable of inactivating motility of human sperm, antigen defined by said monoclonal antibody and methods of using said monoclonal antibody and antigen
IL106255A0 (en) * 1993-04-23 1993-11-15 Baxter Int Method for isolating human blood cells

Also Published As

Publication number Publication date
JP2001517427A (ja) 2001-10-09
CN1280611A (zh) 2001-01-17
AU9508998A (en) 1999-04-12
WO1999015628A1 (fr) 1999-04-01
EP1017790A1 (fr) 2000-07-12

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Legal Events

Date Code Title Description
FZDE Discontinued