CA2293426C - Method and apparatus for detecting microparticles in fluid samples - Google Patents

Method and apparatus for detecting microparticles in fluid samples Download PDF

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Publication number
CA2293426C
CA2293426C CA002293426A CA2293426A CA2293426C CA 2293426 C CA2293426 C CA 2293426C CA 002293426 A CA002293426 A CA 002293426A CA 2293426 A CA2293426 A CA 2293426A CA 2293426 C CA2293426 C CA 2293426C
Authority
CA
Canada
Prior art keywords
microparticle
fluorescent substance
electromagnetic radiation
sample tube
source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002293426A
Other languages
English (en)
French (fr)
Other versions
CA2293426A1 (en
Inventor
Philippe Goix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EMD Millipore Corp
Original Assignee
Guava Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guava Technologies Inc filed Critical Guava Technologies Inc
Publication of CA2293426A1 publication Critical patent/CA2293426A1/en
Application granted granted Critical
Publication of CA2293426C publication Critical patent/CA2293426C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
CA002293426A 1997-06-09 1998-06-09 Method and apparatus for detecting microparticles in fluid samples Expired - Lifetime CA2293426C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4901297P 1997-06-09 1997-06-09
US60/049,012 1997-06-09
PCT/US1998/011958 WO1998057152A1 (en) 1997-06-09 1998-06-09 Method and apparatus for detecting microparticles in fluid samples

Publications (2)

Publication Number Publication Date
CA2293426A1 CA2293426A1 (en) 1998-12-17
CA2293426C true CA2293426C (en) 2007-05-15

Family

ID=21957617

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002293426A Expired - Lifetime CA2293426C (en) 1997-06-09 1998-06-09 Method and apparatus for detecting microparticles in fluid samples

Country Status (6)

Country Link
EP (2) EP2302368B1 (cg-RX-API-DMAC7.html)
JP (2) JP4754661B2 (cg-RX-API-DMAC7.html)
AU (1) AU7831798A (cg-RX-API-DMAC7.html)
CA (1) CA2293426C (cg-RX-API-DMAC7.html)
ES (1) ES2626646T3 (cg-RX-API-DMAC7.html)
WO (1) WO1998057152A1 (cg-RX-API-DMAC7.html)

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US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US20020028434A1 (en) 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
JP4685229B2 (ja) * 2000-10-31 2011-05-18 オリンパス株式会社 レーザ顕微鏡
WO2002043486A1 (en) 2000-11-29 2002-06-06 Xy, Inc. System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
DE60126775T2 (de) * 2001-10-10 2007-10-31 Borealis Technology Oy Teilchendatenanalyse
NZ538462A (en) 2002-08-01 2008-06-30 Xy Inc Low pressure sperm cell separation system
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
JP2005535346A (ja) 2002-08-15 2005-11-24 エックスワイ，インコーポレイテッド 高分解能フローサイトメーター
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
ES2930062T3 (es) 2003-03-28 2022-12-05 Inguran Llc Aparato para detectar el punto de rotura de un sistema de generación de gotitas
EP1625203B1 (en) 2003-05-15 2015-04-08 Xy, Llc Efficient haploid cell sorting for flow cytometer systems
AU2005228893B2 (en) 2004-03-29 2010-08-19 Inguran, Llc Sperm suspensions for sorting into X or Y chromosome-bearing enriched populations
EP1769067A2 (en) 2004-07-22 2007-04-04 Monsanto Technology LLC Process for enriching a population of sperm cells
EP2085762B1 (en) * 2008-01-30 2018-07-04 Palo Alto Research Center Incorporated Transmitting/reflecting emanating light with time variation
CN101672841B (zh) * 2008-09-09 2013-05-08 北京万德高科技发展有限公司 用于生物样品的检测仪器和检测方法
EP2633284B1 (en) * 2010-10-25 2021-08-25 Accuri Cytometers, Inc. Systems and user interface for collecting a data set in a flow cytometer
BR112014001238A2 (pt) 2011-07-19 2017-06-13 Ovizio Imaging Systems N V método para a detecção de células cancerosas e/ou classificação de células numa amostra de células de líquido; sistema para a detecção de células e/ou a classificação de células cancerosas numa amostra de células; método de atualização e/ou melhoria de uma base de dados que compreende os limiares ligados á informação holográfica; e base de dados de objetos
EP2594334A1 (en) 2011-11-21 2013-05-22 Drive O2 Sample vial for digital holographic analysis of a liquid cell sample
EP2626686A1 (en) 2012-02-13 2013-08-14 Ovizio Imaging Systems NV/SA Flow cytometer with digital holographic microscope
US9904248B2 (en) 2012-09-20 2018-02-27 Ovizio Imaging Systems NV/SA Digital holographic microscope with fluid systems
EP3196631A1 (en) 2016-01-19 2017-07-26 Ovizio Imaging Systems NV/SA Digital holographic microscope with electro-fluidic system, said electro-fluidic system and methods of use
CN109270032B (zh) * 2018-08-20 2021-08-20 杭州腾海科技有限公司 一种水体藻类在线监测装置

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DE3718407A1 (de) * 1987-06-02 1988-12-22 Hund Helmut Gmbh Anordnung fuer die optische analyse von partikelpopulationen in gasen und fluessigkeiten
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JP3102938B2 (ja) * 1991-12-30 2000-10-23 シスメックス株式会社 粒子画像分析装置
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US5726751A (en) * 1995-09-27 1998-03-10 University Of Washington Silicon microchannel optical flow cytometer

Also Published As

Publication number Publication date
EP0988523B1 (en) 2013-08-14
CA2293426A1 (en) 1998-12-17
JP2010017188A (ja) 2010-01-28
EP2302368B1 (en) 2017-04-05
JP2002506522A (ja) 2002-02-26
JP4754661B2 (ja) 2011-08-24
EP2302368A1 (en) 2011-03-30
AU7831798A (en) 1998-12-30
WO1998057152A1 (en) 1998-12-17
EP0988523A1 (en) 2000-03-29
JP4999900B2 (ja) 2012-08-15
ES2626646T3 (es) 2017-07-25

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Effective date: 20180611