CA2292631C - Magnetic cell separation device - Google Patents
Magnetic cell separation device Download PDFInfo
- Publication number
- CA2292631C CA2292631C CA002292631A CA2292631A CA2292631C CA 2292631 C CA2292631 C CA 2292631C CA 002292631 A CA002292631 A CA 002292631A CA 2292631 A CA2292631 A CA 2292631A CA 2292631 C CA2292631 C CA 2292631C
- Authority
- CA
- Canada
- Prior art keywords
- magnets
- adjacent
- polar
- magnet
- interpolar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000926 separation method Methods 0.000 title description 5
- 239000002245 particle Substances 0.000 claims abstract description 11
- 239000000126 substance Substances 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 4
- QJVKUMXDEUEQLH-UHFFFAOYSA-N [B].[Fe].[Nd] Chemical compound [B].[Fe].[Nd] QJVKUMXDEUEQLH-UHFFFAOYSA-N 0.000 claims description 3
- 239000000919 ceramic Substances 0.000 claims description 3
- KPLQYGBQNPPQGA-UHFFFAOYSA-N cobalt samarium Chemical compound [Co].[Sm] KPLQYGBQNPPQGA-UHFFFAOYSA-N 0.000 claims description 3
- 229910001172 neodymium magnet Inorganic materials 0.000 claims description 3
- 229910000938 samarium–cobalt magnet Inorganic materials 0.000 claims description 3
- 230000004907 flux Effects 0.000 abstract description 6
- 239000007788 liquid Substances 0.000 abstract description 6
- 210000004027 cell Anatomy 0.000 description 29
- 239000013024 dilution buffer Substances 0.000 description 7
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 6
- 229940098773 bovine serum albumin Drugs 0.000 description 6
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 6
- 239000002953 phosphate buffered saline Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 239000006249 magnetic particle Substances 0.000 description 5
- 210000003819 peripheral blood mononuclear cell Anatomy 0.000 description 5
- 239000011554 ferrofluid Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000006228 supernatant Substances 0.000 description 3
- 241000283707 Capra Species 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000013598 vector Substances 0.000 description 2
- 229910052684 Cerium Inorganic materials 0.000 description 1
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 description 1
- 108010013709 Leukocyte Common Antigens Proteins 0.000 description 1
- 229910052779 Neodymium Inorganic materials 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229910052777 Praseodymium Inorganic materials 0.000 description 1
- 229910052772 Samarium Inorganic materials 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 238000002659 cell therapy Methods 0.000 description 1
- GWXLDORMOJMVQZ-UHFFFAOYSA-N cerium Chemical compound [Ce] GWXLDORMOJMVQZ-UHFFFAOYSA-N 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000000696 magnetic material Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 210000005087 mononuclear cell Anatomy 0.000 description 1
- QEFYFXOXNSNQGX-UHFFFAOYSA-N neodymium atom Chemical compound [Nd] QEFYFXOXNSNQGX-UHFFFAOYSA-N 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- PUDIUYLPXJFUGB-UHFFFAOYSA-N praseodymium atom Chemical compound [Pr] PUDIUYLPXJFUGB-UHFFFAOYSA-N 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 229910052761 rare earth metal Inorganic materials 0.000 description 1
- 150000002910 rare earth metals Chemical class 0.000 description 1
- KZUNJOHGWZRPMI-UHFFFAOYSA-N samarium atom Chemical compound [Sm] KZUNJOHGWZRPMI-UHFFFAOYSA-N 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/035—Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- H01F7/00—Magnets
- H01F7/02—Permanent magnets [PM]
- H01F7/0273—Magnetic circuits with PM for magnetic field generation
- H01F7/0278—Magnetic circuits with PM for magnetic field generation for generating uniform fields, focusing, deflecting electrically charged particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/22—Details of magnetic or electrostatic separation characterised by the magnetic field, e.g. its shape or generation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
Landscapes
- Physics & Mathematics (AREA)
- Electromagnetism (AREA)
- Engineering & Computer Science (AREA)
- Power Engineering (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Centrifugal Separators (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/868,598 US6451207B1 (en) | 1997-06-04 | 1997-06-04 | Magnetic cell separation device |
| US08/868,598 | 1997-06-04 | ||
| PCT/US1998/011816 WO1998055236A1 (en) | 1997-06-04 | 1998-06-04 | Magnetic cell separation device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2292631A1 CA2292631A1 (en) | 1998-12-10 |
| CA2292631C true CA2292631C (en) | 2008-01-15 |
Family
ID=25351973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002292631A Expired - Lifetime CA2292631C (en) | 1997-06-04 | 1998-06-04 | Magnetic cell separation device |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6451207B1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP0986436B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4444377B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE274376T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU753848B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2292631C (cg-RX-API-DMAC7.html) |
| DE (1) | DE69825890T2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO1998055236A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6413420B1 (en) * | 2000-03-17 | 2002-07-02 | Dexter Magnetic Technologies, Inc. | Magnetic separation device |
| FR2826592B1 (fr) | 2001-06-27 | 2003-08-15 | Bio Merieux | Procede, dispositif, et equipement de separation par voie humide de micro particules magnetiques |
| DE10136060A1 (de) * | 2001-07-25 | 2003-02-13 | Roche Diagnostics Gmbh | System zur Separation von magnetisch anziehbaren Partikeln |
| US20050095228A1 (en) | 2001-12-07 | 2005-05-05 | Fraser John K. | Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders |
| US7651684B2 (en) | 2001-12-07 | 2010-01-26 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in augmenting autologous fat transfer |
| US7771716B2 (en) | 2001-12-07 | 2010-08-10 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
| US9597395B2 (en) | 2001-12-07 | 2017-03-21 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions |
| US7585670B2 (en) | 2001-12-07 | 2009-09-08 | Cytori Therapeutics, Inc. | Automated methods for isolating and using clinically safe adipose derived regenerative cells |
| US8105580B2 (en) | 2001-12-07 | 2012-01-31 | Cytori Therapeutics, Inc. | Methods of using adipose derived stem cells to promote wound healing |
| BR0214772A (pt) | 2001-12-07 | 2007-01-09 | Macropore Biosurgery Inc | sistemas e métodos para o tratamento de pacientes com células lipoaspiradas processadas |
| US6846985B2 (en) | 2002-01-22 | 2005-01-25 | Nanoset, Llc | Magnetically shielded assembly |
| US7162302B2 (en) | 2002-03-04 | 2007-01-09 | Nanoset Llc | Magnetically shielded assembly |
| US20040225213A1 (en) | 2002-01-22 | 2004-11-11 | Xingwu Wang | Magnetic resonance imaging coated assembly |
| US7091412B2 (en) | 2002-03-04 | 2006-08-15 | Nanoset, Llc | Magnetically shielded assembly |
| US7011758B2 (en) * | 2002-02-11 | 2006-03-14 | The Board Of Trustees Of The University Of Illinois | Methods and systems for membrane testing |
| CA2481545A1 (en) | 2002-04-12 | 2003-10-23 | Instrumentation Laboratory Company | Immunoassay probe |
| CN1665790A (zh) * | 2002-05-03 | 2005-09-07 | 莫莱丘莱尔探针公司 | 用于检测和分离磷酸化分子的组合物及方法 |
| US20040140875A1 (en) * | 2003-01-22 | 2004-07-22 | Strom Carl H. | Unipolar magnetic system |
| JP4971787B2 (ja) | 2003-02-20 | 2012-07-11 | サイトリ セラピューティクス インコーポレイテッド | 心臓血管疾患の治療における脂肪組織由来細胞の使用方法 |
| EP1664282A4 (en) * | 2003-09-19 | 2008-04-09 | Newsouth Innovations Pty Ltd | METHOD FOR ISOLATING HEPATOCYTES |
| JP2005128771A (ja) * | 2003-10-23 | 2005-05-19 | Fujitsu Ltd | データファイルシステム、データアクセスサーバ、およびデータアクセスプログラム |
| WO2005065267A2 (en) * | 2003-12-24 | 2005-07-21 | Massachusetts Institute Of Technology | Magnetophoretic cell clarification |
| US8211386B2 (en) | 2004-06-08 | 2012-07-03 | Biokit, S.A. | Tapered cuvette and method of collecting magnetic particles |
| US20060051265A1 (en) * | 2004-09-08 | 2006-03-09 | Health Research, Inc. | Apparatus and method for sorting microstructures in a fluid medium |
| NL1028845C2 (nl) * | 2005-04-22 | 2006-10-24 | Rail Road Systems B V | Inrichting voor het creeren van een substantieel magneetveld vrij gebied omgeven door een gebied met een magneetveld gradient. |
| JP5763875B2 (ja) * | 2005-06-24 | 2015-08-12 | セプマグ、システムズ、ソシエダッド、リミターダＳｅｐｍａｇ Ｓｙｓｔｅｍｓ，Ｓ．Ｌ． | 磁性粒子を分離するためのデバイス及び方法 |
| US20070018764A1 (en) * | 2005-07-19 | 2007-01-25 | Analisi Tecnologica Innovadora Per A Processos | Device and method for separating magnetic particles |
| NL1030761C2 (nl) * | 2005-12-23 | 2007-06-29 | Bakker Holding Son Bv | Werkwijze en inrichting voor het scheiden van vaste deeltjes op basis van dichtheidsverschil. |
| WO2007079149A2 (en) * | 2005-12-28 | 2007-07-12 | The General Hospital Corporation | Blood cell sorting methods and systems |
| US20090304644A1 (en) * | 2006-05-30 | 2009-12-10 | Cytori Therapeutics, Inc. | Systems and methods for manipulation of regenerative cells separated and concentrated from adipose tissue |
| US20100015104A1 (en) * | 2006-07-26 | 2010-01-21 | Cytori Therapeutics, Inc | Generation of adipose tissue and adipocytes |
| WO2008080047A2 (en) * | 2006-12-23 | 2008-07-03 | Baxter International Inc. | Magnetic separation of fine particles from compositions |
| DE102007043281A1 (de) | 2007-09-11 | 2009-05-28 | Sebastian Dr. med. Chakrit Bhakdi | Vorrichtung, Materialien und Verfahren zur Hochgradientenmagnetseparation biologischen Materials |
| WO2010006328A2 (en) * | 2008-07-11 | 2010-01-14 | The General Hospital Corporation | Magnetic apparatus for blood separation |
| WO2010021993A1 (en) | 2008-08-19 | 2010-02-25 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease |
| US20100099076A1 (en) * | 2008-10-16 | 2010-04-22 | Kent State University | Sensitive and rapid detection of viral particles in early viral infection by laser tweezers |
| KR101644534B1 (ko) * | 2009-05-01 | 2016-08-01 | 비미니 테크놀로지스 엘엘씨 | 조직 및 세포 부유화 이식편의 최적화 시스템, 방법 및 조성물 |
| US8845812B2 (en) * | 2009-06-12 | 2014-09-30 | Micron Technology, Inc. | Method for contamination removal using magnetic particles |
| IN2012DN03194A (cg-RX-API-DMAC7.html) | 2009-10-28 | 2015-10-09 | Magnetation Inc | |
| TWI362964B (en) * | 2009-12-23 | 2012-05-01 | Ind Tech Res Inst | Magnetic separation device and method for separating magnetic substances in bio-samples |
| WO2011123477A1 (en) * | 2010-03-29 | 2011-10-06 | Glenn Lane | Spatial segregation of plasma components |
| US20140083948A1 (en) | 2011-03-11 | 2014-03-27 | Guisheng Yang | Magnetic particle scavenging device and method |
| US20120262260A1 (en) * | 2011-04-18 | 2012-10-18 | Exact Sciences Corporation | Magnetic microparticle localization device |
| BR112013026824B1 (pt) | 2011-04-20 | 2021-06-29 | Magglobal Llc | Dispositivo e sistema de separação magnética de alta intensidade |
| US9401260B2 (en) | 2013-03-15 | 2016-07-26 | Glenn Lane Family Limited Liability Limited Partnership | Adjustable mass resolving aperture |
| MX2016003127A (es) | 2013-09-19 | 2016-10-28 | Cytori Therapeutics Inc | Metodos de uso de células derivadas de tejido adiposo en la modulación de dolor y/o fibrosis. |
| JP6289638B2 (ja) * | 2014-07-03 | 2018-03-07 | 三菱電機株式会社 | 渦電流選別装置および渦電流選別方法 |
| US9387486B2 (en) * | 2014-09-30 | 2016-07-12 | Ut-Battelle, Llc | High-gradient permanent magnet apparatus and its use in particle collection |
| EP3609993A1 (en) | 2017-04-13 | 2020-02-19 | Universiteit Antwerpen | Micro algae harvesting methods and devices |
| US10449553B2 (en) * | 2018-03-03 | 2019-10-22 | Yuchen Zhou | Magnetic biological entity separation device and method of use |
| US11278915B1 (en) | 2018-07-20 | 2022-03-22 | NeoGeneStar LLC | Device for capturing and releasing magnetic particles |
| WO2020174005A1 (en) | 2019-02-28 | 2020-09-03 | The Regenerative Group Ltd. | Regenerative combination of plasma and adipose tissue |
| CN110004062B (zh) * | 2019-04-18 | 2022-07-01 | 中国人民解放军第四军医大学 | 分选富集数量极稀少循环肿瘤细胞的装置和方法 |
| EP4344786A1 (en) | 2022-09-27 | 2024-04-03 | Sepmag Systems, S.L. | Biomagnetic separation system with double ring profile |
| WO2025145622A1 (zh) * | 2024-01-04 | 2025-07-10 | 北京麦戈龙生物科技有限公司 | 磁性粒子分离装置 |
| CN117884254B (zh) * | 2024-01-04 | 2025-02-25 | 北京麦戈龙科技有限公司 | 磁性粒子分离装置 |
| CN117839863B (zh) * | 2024-01-04 | 2025-02-25 | 北京麦戈龙科技有限公司 | 磁性粒子分离装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3365599A (en) | 1965-03-17 | 1968-01-23 | Wehr Corp | Magnetic circuit |
| GB1202100A (en) | 1967-10-18 | 1970-08-12 | Bethlehem Steel Corp | Magnetic separator method and apparatus |
| US5622831A (en) | 1990-09-26 | 1997-04-22 | Immunivest Corporation | Methods and devices for manipulation of magnetically collected material |
| US5466574A (en) | 1991-03-25 | 1995-11-14 | Immunivest Corporation | Apparatus and methods for magnetic separation featuring external magnetic means |
| US5269915A (en) | 1993-04-08 | 1993-12-14 | Colonel Clair | Magnetic source and condenser for producing flux perpendicular to gas and liquid flow in ferrous and nonferrous pipes |
| JP2788861B2 (ja) * | 1994-11-30 | 1998-08-20 | 株式会社チップトン | 磁気選別装置及びそれに用いられる払拭ブラシ |
-
1997
- 1997-06-04 US US08/868,598 patent/US6451207B1/en not_active Expired - Lifetime
-
1998
- 1998-06-04 DE DE69825890T patent/DE69825890T2/de not_active Expired - Lifetime
- 1998-06-04 WO PCT/US1998/011816 patent/WO1998055236A1/en not_active Ceased
- 1998-06-04 AT AT98928931T patent/ATE274376T1/de not_active IP Right Cessation
- 1998-06-04 AU AU80616/98A patent/AU753848B2/en not_active Expired
- 1998-06-04 CA CA002292631A patent/CA2292631C/en not_active Expired - Lifetime
- 1998-06-04 JP JP50303499A patent/JP4444377B2/ja not_active Expired - Lifetime
- 1998-06-04 EP EP98928931A patent/EP0986436B1/en not_active Expired - Lifetime
-
2002
- 2002-09-13 US US10/244,126 patent/US6572778B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6572778B2 (en) | 2003-06-03 |
| DE69825890T2 (de) | 2005-09-08 |
| EP0986436A1 (en) | 2000-03-22 |
| ATE274376T1 (de) | 2004-09-15 |
| DE69825890D1 (de) | 2004-09-30 |
| WO1998055236A1 (en) | 1998-12-10 |
| EP0986436B1 (en) | 2004-08-25 |
| JP2002504852A (ja) | 2002-02-12 |
| US6451207B1 (en) | 2002-09-17 |
| CA2292631A1 (en) | 1998-12-10 |
| US20030015474A1 (en) | 2003-01-23 |
| AU753848B2 (en) | 2002-10-31 |
| AU8061698A (en) | 1998-12-21 |
| JP4444377B2 (ja) | 2010-03-31 |
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