CA2291608A1 - Recepteurs du facteur neurotrope - Google Patents

Recepteurs du facteur neurotrope Download PDF

Info

Publication number
CA2291608A1
CA2291608A1 CA002291608A CA2291608A CA2291608A1 CA 2291608 A1 CA2291608 A1 CA 2291608A1 CA 002291608 A CA002291608 A CA 002291608A CA 2291608 A CA2291608 A CA 2291608A CA 2291608 A1 CA2291608 A1 CA 2291608A1
Authority
CA
Canada
Prior art keywords
gdnf
gdnfr
neurotrophic factor
found
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002291608A
Other languages
English (en)
Other versions
CA2291608C (fr
Inventor
Gary M. Fox
Shuqian Jing
Duanzhi Wen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc.
Gary M. Fox
Shuqian Jing
Duanzhi Wen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/866,354 external-priority patent/US7138251B1/en
Application filed by Amgen Inc., Gary M. Fox, Shuqian Jing, Duanzhi Wen filed Critical Amgen Inc.
Publication of CA2291608A1 publication Critical patent/CA2291608A1/fr
Application granted granted Critical
Publication of CA2291608C publication Critical patent/CA2291608C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002291608A 1997-05-30 1998-04-27 Recepteurs du facteur neurotrope Expired - Lifetime CA2291608C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/866,354 US7138251B1 (en) 1996-04-22 1997-05-30 Polynucleotides encoding a neurotrophic factor receptor
US08/866,354 1997-05-30
PCT/US1998/008486 WO1998054213A2 (fr) 1997-05-30 1998-04-27 Recepteurs du facteur neurotrope

Publications (2)

Publication Number Publication Date
CA2291608A1 true CA2291608A1 (fr) 1998-12-03
CA2291608C CA2291608C (fr) 2004-04-13

Family

ID=25347430

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002291608A Expired - Lifetime CA2291608C (fr) 1997-05-30 1998-04-27 Recepteurs du facteur neurotrope

Country Status (6)

Country Link
EP (1) EP0983354A2 (fr)
JP (1) JP2002505576A (fr)
AU (1) AU7165998A (fr)
CA (1) CA2291608C (fr)
WO (1) WO1998054213A2 (fr)
ZA (1) ZA984404B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696259B1 (en) 1995-11-13 2004-02-24 Licentia Ltd. Assays using glial cell line-derived neurotrophic factor receptors
US6677135B1 (en) 1996-05-08 2004-01-13 Biogen, Inc. Ret ligand (RetL) for stimulating neutral and renal growth
AU741208B2 (en) * 1997-05-22 2001-11-22 Urmas Arumae Glial cell line-derived neurotrophic factor receptors
US7026138B1 (en) 1998-03-23 2006-04-11 Genentech, Inc. Polynucleotides encoding GFRα3
NZ506748A (en) * 1998-03-23 2002-10-25 Genentech Inc Nucleic acids encoding a GFR alpha 3 polypeptide; host cell and vectors for production of the GRF alpha 3 protein and an assay for detecting GRFalpha 3 production
DE19816186A1 (de) * 1998-04-14 1999-10-21 Univ Muenchen L Maximilians GDNF-kodierende DNA, Teile davon und GDNF-Varianten
EP3538560A4 (fr) 2016-11-10 2020-06-17 Keros Therapeutics, Inc. Polypeptides de fusion gdnf et leurs procédés d'utilisation
KR20220079857A (ko) * 2019-09-13 2022-06-14 루트거스, 더 스테이트 유니버시티 오브 뉴 저지 Aav-상용성 라미닌-링커 중합 단백질

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4006054A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Verfahren zur immunologischen bestimmung von liganden
DK0802800T3 (da) * 1993-08-12 2002-10-07 Neurotech Sa Biokompatible immunoisolatoriske kapsler indeholdende genetisk ændrede celler for levering af biologisk aktive molekyler
US6455277B1 (en) * 1996-04-22 2002-09-24 Amgen Inc. Polynucleotides encoding human glial cell line-derived neurotrophic factor receptor polypeptides
EE9800377A (et) * 1996-05-08 1999-04-15 Biogen, Incorporated Ret-i ligand (RetL) närvi- ja neerukasvu stimuleerimiseks
EP0846764A3 (fr) * 1996-11-27 1998-09-30 Smithkline Beecham Plc Famille de facteurs alpha neurotrophiques des cellules gliales
ES2258295T3 (es) * 1997-02-18 2006-08-16 Genentech, Inc. Receptor de la neurturina.

Also Published As

Publication number Publication date
CA2291608C (fr) 2004-04-13
EP0983354A2 (fr) 2000-03-08
AU7165998A (en) 1998-12-30
ZA984404B (en) 1998-12-01
WO1998054213A2 (fr) 1998-12-03
JP2002505576A (ja) 2002-02-19
WO1998054213A3 (fr) 1999-01-07

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