CA2288373C - Human cerberus protein - Google Patents
Human cerberus protein Download PDFInfo
- Publication number
- CA2288373C CA2288373C CA2288373A CA2288373A CA2288373C CA 2288373 C CA2288373 C CA 2288373C CA 2288373 A CA2288373 A CA 2288373A CA 2288373 A CA2288373 A CA 2288373A CA 2288373 C CA2288373 C CA 2288373C
- Authority
- CA
- Canada
- Prior art keywords
- human cerberus
- protein
- human
- bmp
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000010396 two-hybrid screening Methods 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
- 108010027345 wheylin-1 peptide Proteins 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4442797P | 1997-04-29 | 1997-04-29 | |
| US4515797P | 1997-04-30 | 1997-04-30 | |
| US60/045,157 | 1997-04-30 | ||
| US60/044,427 | 1997-04-30 | ||
| PCT/US1998/006324 WO1998049296A1 (en) | 1997-04-29 | 1998-03-31 | Human cerberus protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2288373A1 CA2288373A1 (en) | 1998-11-05 |
| CA2288373C true CA2288373C (en) | 2010-06-01 |
Family
ID=26721541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2288373A Expired - Lifetime CA2288373C (en) | 1997-04-29 | 1998-03-31 | Human cerberus protein |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6610510B1 (enExample) |
| EP (1) | EP0975752A1 (enExample) |
| JP (1) | JP4062551B2 (enExample) |
| AU (1) | AU726385B2 (enExample) |
| CA (1) | CA2288373C (enExample) |
| IL (1) | IL132443A0 (enExample) |
| NZ (1) | NZ500577A (enExample) |
| WO (1) | WO1998049296A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6150328A (en) | 1986-07-01 | 2000-11-21 | Genetics Institute, Inc. | BMP products |
| US6291206B1 (en) | 1993-09-17 | 2001-09-18 | Genetics Institute, Inc. | BMP receptor proteins |
| DK0733109T3 (da) | 1993-12-07 | 2006-07-03 | Genetics Inst Llc | BMP-12, BMP-13 og seneinducerende præparater dermed |
| WO1999061044A1 (en) * | 1998-05-28 | 1999-12-02 | The Board Of Trustees Of The University Of Arkansas | Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption |
| US6395511B1 (en) * | 1998-11-27 | 2002-05-28 | Darwin Discovery, Ltd. | Nucleic acids encoding a novel family of TGF-β binding proteins from humans |
| US6727224B1 (en) | 1999-02-01 | 2004-04-27 | Genetics Institute, Llc. | Methods and compositions for healing and repair of articular cartilage |
| US7189392B1 (en) | 1999-10-15 | 2007-03-13 | Genetics Institute, Llc | Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins |
| CA2449008A1 (en) | 2001-06-01 | 2002-12-12 | Wyeth | Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins |
| EP1801240A1 (en) * | 2001-06-05 | 2007-06-27 | Auckland Uniservices Limited | Methods and compositions for assessment of pulmonary function and disorders |
| WO2002100426A1 (en) * | 2001-06-08 | 2002-12-19 | Smith & Nephew Plc | Bmp binding proteins for use in bone or cartilage regeneration |
| TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
| GB2385052A (en) | 2002-02-05 | 2003-08-13 | Leuven K U Res & Dev | Treatment of spondyloarthropathies |
| US7193069B2 (en) | 2002-03-22 | 2007-03-20 | Research Association For Biotechnology | Full-length cDNA |
| WO2004062621A2 (en) * | 2003-01-13 | 2004-07-29 | Georgia Tech Research Corporation | Anti-inflammatory agents and methods of their use |
| WO2005115439A2 (en) * | 2004-05-27 | 2005-12-08 | Acceleron Pharma Inc. | Cerberus/coco derivatives and uses thereof |
| US9045553B2 (en) | 2004-05-27 | 2015-06-02 | Acceleron Pharma, Inc. | Cerberus/Coco derivatives and uses thereof |
| CA2608142A1 (en) * | 2005-05-10 | 2006-11-16 | Synergenz Bioscience Limited | Methods and compositions for assessment of pulmonary function and disorders |
| JP2008545390A (ja) * | 2005-05-19 | 2008-12-18 | シナージェンズ バイオサイエンス リミティド | 遺伝的多型を用いた肺癌を発達させるリスクの評価方法 |
| AU2006248200A1 (en) * | 2005-05-19 | 2006-11-23 | Synergenz Bioscience Limited | Methods and compositions for assessment of pulmonary function and disorders |
| AU2006248189A1 (en) * | 2005-05-20 | 2006-11-23 | Synergenz Bioscience Limited | Methods of analysis of polymorphisms and uses thereof |
| WO2007142818A2 (en) * | 2006-05-17 | 2007-12-13 | Stryker Corporation | Use of a soluble morphogenic protein complex for treating cartilage defects |
| WO2008073351A2 (en) * | 2006-12-08 | 2008-06-19 | Acceleron Pharma Inc. | Uses of cerberus, coco and derivatives thereof |
| CN105759056B (zh) * | 2016-04-06 | 2017-11-14 | 四川大学华西医院 | 一种肺癌筛查试剂盒 |
| JP2020502218A (ja) | 2016-12-21 | 2020-01-23 | メレオ バイオファーマ ３ リミテッド | 骨形成不全症の処置における抗スクレロスチン抗体の使用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4952499A (en) * | 1988-02-11 | 1990-08-28 | Dana-Farber Cancer Institute | Genes and their encoded proteins which regulate gene expression of the interleukin-2 receptor and of human lymphotropic retroviruses |
| US6133232A (en) * | 1996-06-20 | 2000-10-17 | The Regents Of The University Of California | Endoderm, cardiac and neural inducing factors |
-
1998
- 1998-03-31 JP JP54698998A patent/JP4062551B2/ja not_active Expired - Lifetime
- 1998-03-31 CA CA2288373A patent/CA2288373C/en not_active Expired - Lifetime
- 1998-03-31 US US09/423,029 patent/US6610510B1/en not_active Expired - Lifetime
- 1998-03-31 EP EP98914368A patent/EP0975752A1/en not_active Withdrawn
- 1998-03-31 IL IL13244398A patent/IL132443A0/xx unknown
- 1998-03-31 WO PCT/US1998/006324 patent/WO1998049296A1/en not_active Ceased
- 1998-03-31 NZ NZ500577A patent/NZ500577A/xx not_active IP Right Cessation
- 1998-03-31 AU AU68736/98A patent/AU726385B2/en not_active Expired
-
2003
- 2003-06-19 US US10/465,474 patent/US7241739B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0975752A1 (en) | 2000-02-02 |
| JP4062551B2 (ja) | 2008-03-19 |
| US6610510B1 (en) | 2003-08-26 |
| NZ500577A (en) | 2001-02-23 |
| CA2288373A1 (en) | 1998-11-05 |
| AU6873698A (en) | 1998-11-24 |
| US20030199042A1 (en) | 2003-10-23 |
| WO1998049296A1 (en) | 1998-11-05 |
| AU726385B2 (en) | 2000-11-02 |
| US7241739B2 (en) | 2007-07-10 |
| JP2001526535A (ja) | 2001-12-18 |
| IL132443A0 (en) | 2001-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20180403 |
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| MKEX | Expiry |
Effective date: 20180403 |