AU726385B2 - Human cerberus protein - Google Patents

Human cerberus protein Download PDF

Info

Publication number
AU726385B2
AU726385B2 AU68736/98A AU6873698A AU726385B2 AU 726385 B2 AU726385 B2 AU 726385B2 AU 68736/98 A AU68736/98 A AU 68736/98A AU 6873698 A AU6873698 A AU 6873698A AU 726385 B2 AU726385 B2 AU 726385B2
Authority
AU
Australia
Prior art keywords
human
cerberus
human cerberus
bmp
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU68736/98A
Other languages
English (en)
Other versions
AU6873698A (en
Inventor
Aris N. Economides
Eduardo A. Rojas
Neil E. Stahl
David M Valenzuela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
Original Assignee
Regeneron Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26721541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU726385(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharmaceuticals Inc filed Critical Regeneron Pharmaceuticals Inc
Publication of AU6873698A publication Critical patent/AU6873698A/en
Application granted granted Critical
Publication of AU726385B2 publication Critical patent/AU726385B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU68736/98A 1997-04-29 1998-03-31 Human cerberus protein Expired AU726385B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4442797P 1997-04-29 1997-04-29
US60/044427 1997-04-29
US4515797P 1997-04-30 1997-04-30
US60/045157 1997-04-30
PCT/US1998/006324 WO1998049296A1 (en) 1997-04-29 1998-03-31 Human cerberus protein

Publications (2)

Publication Number Publication Date
AU6873698A AU6873698A (en) 1998-11-24
AU726385B2 true AU726385B2 (en) 2000-11-02

Family

ID=26721541

Family Applications (1)

Application Number Title Priority Date Filing Date
AU68736/98A Expired AU726385B2 (en) 1997-04-29 1998-03-31 Human cerberus protein

Country Status (8)

Country Link
US (2) US6610510B1 (enExample)
EP (1) EP0975752A1 (enExample)
JP (1) JP4062551B2 (enExample)
AU (1) AU726385B2 (enExample)
CA (1) CA2288373C (enExample)
IL (1) IL132443A0 (enExample)
NZ (1) NZ500577A (enExample)
WO (1) WO1998049296A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
EP0733109B9 (en) 1993-12-07 2006-07-05 Genetics Institute, LLC Bmp-12, bmp-13 and tendon-inducing compositions thereof
WO1999061044A1 (en) * 1998-05-28 1999-12-02 The Board Of Trustees Of The University Of Arkansas Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption
ES2639020T3 (es) * 1998-11-27 2017-10-25 Ucb Pharma S.A. Composiciones y métodos para incrementar la mineralización de la substancia ósea
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
EP1223990B1 (en) 1999-10-15 2004-07-28 Genetics Institute, LLC Formulations of hyaluronic acid for delivery of osteogenic proteins
US7226587B2 (en) 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
WO2002099134A1 (en) * 2001-06-05 2002-12-12 Auckland Uniservices Limited Methods and compositions for assessment of pulmonary function and disorders
EP1399177A1 (en) * 2001-06-08 2004-03-24 Smith & Nephew PLC Bmp binding proteins for use in bone or cartilage regeneration
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
GB2385052A (en) * 2002-02-05 2003-08-13 Leuven K U Res & Dev Treatment of spondyloarthropathies
US7193069B2 (en) * 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
US20060276385A1 (en) * 2003-01-13 2006-12-07 Hanjoong Jo Anti-inflammatory agents and methods of their use
EP1755648A2 (en) * 2004-05-27 2007-02-28 Acceleron Pharma Inc. Cerberus/coco derivatives and uses thereof
US9045553B2 (en) 2004-05-27 2015-06-02 Acceleron Pharma, Inc. Cerberus/Coco derivatives and uses thereof
EP1896607A4 (en) * 2005-05-10 2009-12-16 Synergenz Bioscience Ltd METHOD AND COMPOSITIONS FOR THE ASSESSMENT OF LUNG FUNCTION AND RESPIRATORY DISEASE
JP2008545390A (ja) * 2005-05-19 2008-12-18 シナージェンズ バイオサイエンス リミティド 遺伝的多型を用いた肺癌を発達させるリスクの評価方法
WO2006123954A1 (en) * 2005-05-19 2006-11-23 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
WO2006123943A1 (en) * 2005-05-20 2006-11-23 Synergenz Bioscience Limited Methods of analysis of polymorphisms and uses thereof
US20090298761A1 (en) * 2006-05-17 2009-12-03 Donald Engelman Methods of treating cartilage defects using a soluble morphogenic protein complex
JP2010512326A (ja) * 2006-12-08 2010-04-22 アクセルロン ファーマ， インコーポレイテッド Ｃｅｒｂｅｒｕｓ、Ｃｏｃｏおよびこれらの誘導体の使用
CN105759056B (zh) * 2016-04-06 2017-11-14 四川大学华西医院 一种肺癌筛查试剂盒
US10961305B2 (en) 2016-12-21 2021-03-30 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952499A (en) * 1988-02-11 1990-08-28 Dana-Farber Cancer Institute Genes and their encoded proteins which regulate gene expression of the interleukin-2 receptor and of human lymphotropic retroviruses
US6133232A (en) * 1996-06-20 2000-10-17 The Regents Of The University Of California Endoderm, cardiac and neural inducing factors

Also Published As

Publication number Publication date
AU6873698A (en) 1998-11-24
US7241739B2 (en) 2007-07-10
NZ500577A (en) 2001-02-23
JP2001526535A (ja) 2001-12-18
JP4062551B2 (ja) 2008-03-19
WO1998049296A1 (en) 1998-11-05
EP0975752A1 (en) 2000-02-02
US20030199042A1 (en) 2003-10-23
US6610510B1 (en) 2003-08-26
CA2288373C (en) 2010-06-01
IL132443A0 (en) 2001-03-19
CA2288373A1 (en) 1998-11-05

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FGA Letters patent sealed or granted (standard patent)