NZ500577A - Human cerberus protein that regulates cell function, induce neural development or antagonise bone morphogenic proteins - Google Patents

Human cerberus protein that regulates cell function, induce neural development or antagonise bone morphogenic proteins

Info

Publication number
NZ500577A
NZ500577A NZ500577A NZ50057798A NZ500577A NZ 500577 A NZ500577 A NZ 500577A NZ 500577 A NZ500577 A NZ 500577A NZ 50057798 A NZ50057798 A NZ 50057798A NZ 500577 A NZ500577 A NZ 500577A
Authority
NZ
New Zealand
Prior art keywords
antagonise
cell function
bone morphogenic
morphogenic proteins
regulates cell
Prior art date
Application number
NZ500577A
Other languages
English (en)
Inventor
David M Valenzuela
Eduardo A Rojas
Aris N Economides
Neil E Stahl
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26721541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ500577(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of NZ500577A publication Critical patent/NZ500577A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NZ500577A 1997-04-29 1998-03-31 Human cerberus protein that regulates cell function, induce neural development or antagonise bone morphogenic proteins NZ500577A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4442797P 1997-04-29 1997-04-29
US4515797P 1997-04-30 1997-04-30
PCT/US1998/006324 WO1998049296A1 (en) 1997-04-29 1998-03-31 Human cerberus protein

Publications (1)

Publication Number Publication Date
NZ500577A true NZ500577A (en) 2001-02-23

Family

ID=26721541

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ500577A NZ500577A (en) 1997-04-29 1998-03-31 Human cerberus protein that regulates cell function, induce neural development or antagonise bone morphogenic proteins

Country Status (8)

Country Link
US (2) US6610510B1 (enExample)
EP (1) EP0975752A1 (enExample)
JP (1) JP4062551B2 (enExample)
AU (1) AU726385B2 (enExample)
CA (1) CA2288373C (enExample)
IL (1) IL132443A0 (enExample)
NZ (1) NZ500577A (enExample)
WO (1) WO1998049296A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
DK0733109T3 (da) 1993-12-07 2006-07-03 Genetics Inst Llc BMP-12, BMP-13 og seneinducerende præparater dermed
WO1999061044A1 (en) * 1998-05-28 1999-12-02 The Board Of Trustees Of The University Of Arkansas Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption
US6395511B1 (en) * 1998-11-27 2002-05-28 Darwin Discovery, Ltd. Nucleic acids encoding a novel family of TGF-β binding proteins from humans
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
US7189392B1 (en) 1999-10-15 2007-03-13 Genetics Institute, Llc Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
CA2449008A1 (en) 2001-06-01 2002-12-12 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
EP1801240A1 (en) * 2001-06-05 2007-06-27 Auckland Uniservices Limited Methods and compositions for assessment of pulmonary function and disorders
WO2002100426A1 (en) * 2001-06-08 2002-12-19 Smith & Nephew Plc Bmp binding proteins for use in bone or cartilage regeneration
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
GB2385052A (en) 2002-02-05 2003-08-13 Leuven K U Res & Dev Treatment of spondyloarthropathies
US7193069B2 (en) 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
WO2004062621A2 (en) * 2003-01-13 2004-07-29 Georgia Tech Research Corporation Anti-inflammatory agents and methods of their use
WO2005115439A2 (en) * 2004-05-27 2005-12-08 Acceleron Pharma Inc. Cerberus/coco derivatives and uses thereof
US9045553B2 (en) 2004-05-27 2015-06-02 Acceleron Pharma, Inc. Cerberus/Coco derivatives and uses thereof
CA2608142A1 (en) * 2005-05-10 2006-11-16 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
JP2008545390A (ja) * 2005-05-19 2008-12-18 シナージェンズ バイオサイエンス リミティド 遺伝的多型を用いた肺癌を発達させるリスクの評価方法
AU2006248200A1 (en) * 2005-05-19 2006-11-23 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
AU2006248189A1 (en) * 2005-05-20 2006-11-23 Synergenz Bioscience Limited Methods of analysis of polymorphisms and uses thereof
WO2007142818A2 (en) * 2006-05-17 2007-12-13 Stryker Corporation Use of a soluble morphogenic protein complex for treating cartilage defects
WO2008073351A2 (en) * 2006-12-08 2008-06-19 Acceleron Pharma Inc. Uses of cerberus, coco and derivatives thereof
CN105759056B (zh) * 2016-04-06 2017-11-14 四川大学华西医院 一种肺癌筛查试剂盒
JP2020502218A (ja) 2016-12-21 2020-01-23 メレオ バイオファーマ ３ リミテッド 骨形成不全症の処置における抗スクレロスチン抗体の使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952499A (en) * 1988-02-11 1990-08-28 Dana-Farber Cancer Institute Genes and their encoded proteins which regulate gene expression of the interleukin-2 receptor and of human lymphotropic retroviruses
US6133232A (en) * 1996-06-20 2000-10-17 The Regents Of The University Of California Endoderm, cardiac and neural inducing factors

Also Published As

Publication number Publication date
EP0975752A1 (en) 2000-02-02
JP4062551B2 (ja) 2008-03-19
US6610510B1 (en) 2003-08-26
CA2288373A1 (en) 1998-11-05
CA2288373C (en) 2010-06-01
AU6873698A (en) 1998-11-24
US20030199042A1 (en) 2003-10-23
WO1998049296A1 (en) 1998-11-05
AU726385B2 (en) 2000-11-02
US7241739B2 (en) 2007-07-10
JP2001526535A (ja) 2001-12-18
IL132443A0 (en) 2001-03-19

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