CA2285479A1 - (s) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate, its application to the treatment of chronic pain - Google Patents

(s) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate, its application to the treatment of chronic pain Download PDF

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Publication number
CA2285479A1
CA2285479A1 CA002285479A CA2285479A CA2285479A1 CA 2285479 A1 CA2285479 A1 CA 2285479A1 CA 002285479 A CA002285479 A CA 002285479A CA 2285479 A CA2285479 A CA 2285479A CA 2285479 A1 CA2285479 A1 CA 2285479A1
Authority
CA
Canada
Prior art keywords
phenyl
methylamino
butyl
trimethoxybenzoate
enantiomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002285479A
Other languages
English (en)
French (fr)
Inventor
Francois Joseph Roman
Agnes Grouhel
Svein Gunwald Dahl
Henry Jacobelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PARKE-DAVIS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2285479A1 publication Critical patent/CA2285479A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002285479A 1997-06-30 1998-06-23 (s) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate, its application to the treatment of chronic pain Abandoned CA2285479A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR97/08323 1997-06-30
FR9708323A FR2765218B1 (fr) 1997-06-30 1997-06-30 Le (s) 3,4,5-trimethoxybenzoate de 2-methylamino-2-phenyl-n- butyle, son application au traitement des douleurs chroniques
PCT/EP1998/003825 WO1999001417A1 (en) 1997-06-30 1998-06-23 (S) 2-METHYLAMINO-2-PHENYL-n-BUTYL 3,4,5-TRIMETHOXYBENZOATE, ITS APPLICATION TO THE TREATMENT OF CHRONIC PAIN

Publications (1)

Publication Number Publication Date
CA2285479A1 true CA2285479A1 (en) 1999-01-14

Family

ID=9508729

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002285479A Abandoned CA2285479A1 (en) 1997-06-30 1998-06-23 (s) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate, its application to the treatment of chronic pain

Country Status (16)

Country Link
EP (1) EP0993436A1 (is)
JP (1) JP2002508776A (is)
KR (1) KR20010014294A (is)
AU (1) AU731887B2 (is)
BR (1) BR9810387A (is)
CA (1) CA2285479A1 (is)
FR (1) FR2765218B1 (is)
HU (1) HUP0003023A3 (is)
IL (1) IL133398A0 (is)
IS (1) IS5324A (is)
MX (1) MXPA99009120A (is)
NO (1) NO996496D0 (is)
NZ (1) NZ500212A (is)
PL (1) PL337665A1 (is)
WO (1) WO1999001417A1 (is)
ZA (1) ZA985668B (is)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013134869A1 (en) * 2012-03-12 2013-09-19 Gicare Pharma Inc. Novel sulfonate-based trimebutine salts

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1110549A1 (en) 1999-12-23 2001-06-27 Warner-Lambert Company Use of trimebutine for treating pain
FR2927076B1 (fr) 2008-01-31 2010-03-26 Oroxcell Derives de 2-amino-2-phenyl-alkanol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2948660B1 (fr) * 2009-07-30 2011-08-19 Oroxcell Derives de 2-amino-2-phenyl-alkanol, leur preparation et les compositions pharmaceutiques qui les contiennent
RU2752086C1 (ru) * 2020-04-27 2021-07-22 Общество С Ограниченной Ответственностью "Валента-Интеллект" Новое соединение [2-(диметиламино)-2-фенилбутил]-3,4,5-триметоксибензоата 4-метил-2н-хромен-2-он-7-илсульфат и его применение

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434826A (en) * 1973-11-14 1976-05-05 Gallardo Antonio Sa Esters and carbamates of aminoalkanols

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013134869A1 (en) * 2012-03-12 2013-09-19 Gicare Pharma Inc. Novel sulfonate-based trimebutine salts

Also Published As

Publication number Publication date
HUP0003023A2 (hu) 2001-01-29
AU731887B2 (en) 2001-04-05
FR2765218B1 (fr) 1999-08-13
MXPA99009120A (es) 2005-01-10
IS5324A (is) 1999-12-28
HUP0003023A3 (en) 2001-12-28
IL133398A0 (en) 2001-04-30
NZ500212A (en) 2001-07-27
NO996496L (no) 1999-12-27
AU8540598A (en) 1999-01-25
JP2002508776A (ja) 2002-03-19
WO1999001417A1 (en) 1999-01-14
BR9810387A (pt) 2000-09-05
KR20010014294A (ko) 2001-02-26
NO996496D0 (no) 1999-12-27
EP0993436A1 (en) 2000-04-19
ZA985668B (en) 1999-01-25
FR2765218A1 (fr) 1998-12-31
PL337665A1 (en) 2000-08-28

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued