CA2282809A1 - Cytochrome p450 monooxygenases - Google Patents

Cytochrome p450 monooxygenases Download PDF

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Publication number
CA2282809A1
CA2282809A1 CA002282809A CA2282809A CA2282809A1 CA 2282809 A1 CA2282809 A1 CA 2282809A1 CA 002282809 A CA002282809 A CA 002282809A CA 2282809 A CA2282809 A CA 2282809A CA 2282809 A1 CA2282809 A1 CA 2282809A1
Authority
CA
Canada
Prior art keywords
monooxygenase
cytochrome
plant
conversion
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002282809A
Other languages
English (en)
French (fr)
Inventor
Barbara Ann Halkier
Soren Bak
Rachel Alice Kahn
Birger Lindberg Moller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Københavns Universitet
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/EP1998/001253 external-priority patent/WO1998040470A2/en
Publication of CA2282809A1 publication Critical patent/CA2282809A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8285—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002282809A 1997-03-07 1998-03-05 Cytochrome p450 monooxygenases Abandoned CA2282809A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP97810132.7 1997-03-07
EP97810132 1997-03-07
EP97810954.4 1997-12-08
EP97810954 1997-12-08
PCT/EP1998/001253 WO1998040470A2 (en) 1997-03-07 1998-03-05 Cytochrome p450 monooxygenases

Publications (1)

Publication Number Publication Date
CA2282809A1 true CA2282809A1 (en) 1998-09-17

Family

ID=56289831

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002282809A Abandoned CA2282809A1 (en) 1997-03-07 1998-03-05 Cytochrome p450 monooxygenases

Country Status (7)

Country Link
US (1) US6300544B1 (enExample)
EP (1) EP0970191A2 (enExample)
JP (1) JP2001514515A (enExample)
KR (1) KR100583538B1 (enExample)
BR (1) BR9808825A (enExample)
CA (1) CA2282809A1 (enExample)
PL (1) PL335643A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7009088B1 (en) 2000-12-18 2006-03-07 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods of modulating auxin production in plants
JP2005512532A (ja) * 2001-08-03 2005-05-12 ディヴァーサ コーポレイション P450酵素、それらをコードした核酸及びそれらの作製と使用
KR100454237B1 (ko) * 2002-04-22 2004-10-26 한국과학기술원 알데히드옥심으로부터 니트릴의 제조방법
US20030228579A1 (en) * 2002-06-05 2003-12-11 Uri Alon Ordering genes by analysis of expression kinetics
US20070130640A1 (en) * 2005-12-06 2007-06-07 The Arizona Board Of Regents On Behalf Of The University Of Arizona A Arizona Corporation, Methods of modulating auxin production in plants
KR100834378B1 (ko) * 2007-01-19 2008-06-02 명지대학교 산학협력단 식물의 정단 우성을 강화시키는 시토크롬 p450 유전자
KR100834380B1 (ko) * 2007-01-19 2008-06-02 명지대학교 산학협력단 식물의 수분 스트레스 저항성을 증가시키는 시토크롬p450 유전자
CL2008001592A1 (es) * 2007-05-30 2009-03-06 Syngenta Participations Ag Celula vegetal que comprende una construccion de acido nucleico que contine una secuencia nucleotidica que codifica un citocromo p450, y metodo para conferir resistencia a un herbicida en la planta basado en la transformacion de la construccion descrita anteriormente.
EP3156489B1 (en) 2009-01-22 2019-03-06 Syngenta Participations Ag Mutant hydroxyphenylpyruvate dioxygenase polypeptides and methods of use
AU2010326672A1 (en) 2009-07-10 2011-08-04 Syngenta Participations Ag Novel hydroxyphenylpyruvate dioxygenase polypeptides and methods of use
TWI667347B (zh) 2010-12-15 2019-08-01 瑞士商先正達合夥公司 大豆品種syht0h2及偵測其之組合物及方法
AR100017A1 (es) 2013-08-12 2016-09-07 Basf Se Hidroxifenilpiruvato dioxigenasas resistentes a herbicidas
WO2016128470A1 (en) 2015-02-11 2016-08-18 Basf Se Herbicide-resistant hydroxyphenylpyruvate dioxygenases
MX389329B (es) 2015-06-17 2025-03-11 Basf Agro Bv Plantas que tienen una mayor tolerancia a herbicidas.
US11959086B2 (en) 2016-05-20 2024-04-16 BASF Agro B.V. Dual transit peptides for targeting polypeptides
BR112019001483A2 (pt) 2016-07-27 2019-09-10 Basf Agro Bv método para controlar a vegetação indesejada em um local de cultivo de plantas
CR20200233A (es) 2017-11-29 2020-10-02 Basf Se Plantas que tienen una mayor tolerancia a herbicidas
BE1029146B1 (fr) * 2021-02-26 2022-09-26 Xpress Biologics Procede de purification d'une proteine d'interet
CN117897378A (zh) 2021-09-03 2024-04-16 巴斯夫农业种子解决方案美国有限责任公司 对除草剂具有增加的耐受性的植物
WO2025038723A1 (en) 2023-08-14 2025-02-20 The Texas A&M University System Corn endotype-derived polypeptides capable of metabolizing fumonisin
WO2025153595A1 (en) 2024-01-17 2025-07-24 Basf Se Plants having increased tolerance to herbicides
AR134940A1 (es) 2024-01-17 2026-05-13 Basf Se Plantas que tienen una mayor tolerancia a herbicidas

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022441A1 (en) 1992-04-23 1993-11-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Dna sequence of a plant resistance gene
CA2176949A1 (en) 1993-12-08 1995-06-15 Birgit Maria Koch Cytochrome p-450 monooxygenases

Also Published As

Publication number Publication date
EP0970191A2 (en) 2000-01-12
PL335643A1 (en) 2000-05-08
US6300544B1 (en) 2001-10-09
BR9808825A (pt) 2000-07-04
AU723454B2 (en) 2000-08-24
KR20000076045A (ko) 2000-12-26
JP2001514515A (ja) 2001-09-11
KR100583538B1 (ko) 2006-05-26
AU6727898A (en) 1998-09-29

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EEER Examination request
FZDE Discontinued