CA2280966C - Materiau implantable de type mastic, a base de collagene - Google Patents

Materiau implantable de type mastic, a base de collagene Download PDF

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Publication number
CA2280966C
CA2280966C CA2280966A CA2280966A CA2280966C CA 2280966 C CA2280966 C CA 2280966C CA 2280966 A CA2280966 A CA 2280966A CA 2280966 A CA2280966 A CA 2280966A CA 2280966 C CA2280966 C CA 2280966C
Authority
CA
Canada
Prior art keywords
acid
collagen
putty material
putty
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2280966A
Other languages
English (en)
Other versions
CA2280966A1 (fr
Inventor
James A. Benedict
Christopher J. Damien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zimmer Orthobiologics Inc
Original Assignee
Zimmer Orthobiologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zimmer Orthobiologics Inc filed Critical Zimmer Orthobiologics Inc
Publication of CA2280966A1 publication Critical patent/CA2280966A1/fr
Application granted granted Critical
Publication of CA2280966C publication Critical patent/CA2280966C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/102—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne des compositions pour matériau implantable de type mastic, qui permet d'administrer de certains composés actifs à un patient. Plus précisément, l'invention concerne un matériau dont le pH est compris entre environ 3 et 6 et qui possède les propriétés physiques caractéristiques d'un matériau de type mastic, sachant que ledit matériau renferme du collagène et de l'eau. L'invention concerne également un procédé relatif à l'utilisation de ce matériau implantable de type mastic.
CA2280966A 1997-02-13 1998-02-12 Materiau implantable de type mastic, a base de collagene Expired - Lifetime CA2280966C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3707197P 1997-02-13 1997-02-13
US60/037,071 1997-02-13
PCT/US1998/002751 WO1998035653A1 (fr) 1997-02-13 1998-02-12 Materiau implantable de type mastic, a base de collagene

Publications (2)

Publication Number Publication Date
CA2280966A1 CA2280966A1 (fr) 1998-08-20
CA2280966C true CA2280966C (fr) 2012-04-17

Family

ID=21892280

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2280966A Expired - Lifetime CA2280966C (fr) 1997-02-13 1998-02-12 Materiau implantable de type mastic, a base de collagene

Country Status (5)

Country Link
EP (1) EP1019027A4 (fr)
JP (1) JP5105216B2 (fr)
AU (1) AU6654598A (fr)
CA (1) CA2280966C (fr)
WO (1) WO1998035653A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497236B2 (en) 1998-02-13 2013-07-30 Zimmer Orthobiologics, Inc. Implantable putty material
US8613938B2 (en) 2010-11-15 2013-12-24 Zimmer Orthobiologics, Inc. Bone void fillers
US8690874B2 (en) 2000-12-22 2014-04-08 Zimmer Orthobiologics, Inc. Composition and process for bone growth and repair
US8742072B2 (en) 2006-12-21 2014-06-03 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989269A (en) 1996-08-30 1999-11-23 Vts Holdings L.L.C. Method, instruments and kit for autologous transplantation
US6569172B2 (en) 1996-08-30 2003-05-27 Verigen Transplantation Service International (Vtsi) Method, instruments, and kit for autologous transplantation
US6511958B1 (en) 1997-08-14 2003-01-28 Sulzer Biologics, Inc. Compositions for regeneration and repair of cartilage lesions
ATE220564T1 (de) 1997-08-14 2002-08-15 Sulzer Innotec Ag Zusammensetzung und vorrichtung zur reparatur von knorpelgewebe in vivo bestehend aus nanokapseln mit osteoinduktiven und/oder chondroinduktiven faktoren
MXPA01001460A (es) 1998-08-14 2005-06-06 Verigen Transplantation Serv Metodos, instrumentos y materiales para el transplante de celulas condrociticas.
JP2002539172A (ja) 1999-03-17 2002-11-19 ノバルティス アクチエンゲゼルシャフト Ｔｇｆ−ベータを含む医薬組成物
US6576249B1 (en) * 2000-11-13 2003-06-10 El Gendler Bone putty and method
US7132110B2 (en) 2001-08-30 2006-11-07 Isotis Orthobiologics, Inc. Tissue repair compositions and methods for their manufacture and use
US6974862B2 (en) 2003-06-20 2005-12-13 Kensey Nash Corporation High density fibrous polymers suitable for implant
US20050020506A1 (en) * 2003-07-25 2005-01-27 Drapeau Susan J. Crosslinked compositions comprising collagen and demineralized bone matrix, methods of making and methods of use
US20050186240A1 (en) 2004-02-23 2005-08-25 Ringeisen Timothy A. Gel suitable for implantation and delivery system
DE102005045671A1 (de) * 2005-09-15 2007-03-29 Ossacur Ag Verwendung eines Kollagens xenogenen Ursprungs
US7824703B2 (en) * 2006-02-01 2010-11-02 Warsaw Orthopedics, Inc. Medical implants with reservoir(s), and materials preparable from same
US7892577B2 (en) * 2006-02-27 2011-02-22 Globus Medical, Inc. Bone graft materials derived from mineralized gelatin
US20070248575A1 (en) * 2006-04-19 2007-10-25 Jerome Connor Bone graft composition
EP2222348B1 (fr) * 2007-12-21 2013-07-03 RTI Biologics, Inc. Mastics ostéo-inducteurs et leurs procédés de fabrication et d'utilisation
US8840913B2 (en) 2008-03-27 2014-09-23 Warsaw Orthopedic, Inc. Malleable multi-component implants and materials therefor
KR101361810B1 (ko) 2011-12-22 2014-02-12 전북대학교산학협력단 조직공학용 ｄｂｐ 겔
KR102348476B1 (ko) * 2021-03-02 2022-01-06 한국전통문화대학교산학협력단 천연접착제 및 이의 접착강도 향상방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3471598A (en) * 1966-02-14 1969-10-07 Fmc Corp Method of producing absorbent mats
US3443261A (en) * 1967-09-01 1969-05-13 Fmc Corp Prosthetic structures from microcrystalline collagen
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
US4066083A (en) * 1976-06-03 1978-01-03 Pentapharm A.G. Sterile surgical collagen product
WO1981000963A1 (fr) * 1979-10-08 1981-04-16 Pentapharm Ag Procede de preparation d'un produit a base de collagene pour usage medical et cosmetique
DE2967060D1 (en) * 1979-12-18 1984-07-19 Oscobal Ag Bone replacement material and process for producing a bone replacement material
US4394370A (en) * 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4440750A (en) * 1982-02-12 1984-04-03 Collagen Corporation Osteogenic composition and method
CA1259914A (fr) * 1984-07-06 1989-09-26 Donald G. Wallace Methodes de reparation des os a l'aide de collagene
US4969912A (en) * 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US5475052A (en) * 1988-11-21 1995-12-12 Collagen Corporation Collagen-synthetic polymer matrices prepared using a multiple step reaction
US5707962A (en) * 1994-09-28 1998-01-13 Gensci Regeneration Sciences Inc. Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497236B2 (en) 1998-02-13 2013-07-30 Zimmer Orthobiologics, Inc. Implantable putty material
US8690874B2 (en) 2000-12-22 2014-04-08 Zimmer Orthobiologics, Inc. Composition and process for bone growth and repair
US8742072B2 (en) 2006-12-21 2014-06-03 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US8613938B2 (en) 2010-11-15 2013-12-24 Zimmer Orthobiologics, Inc. Bone void fillers

Also Published As

Publication number Publication date
CA2280966A1 (fr) 1998-08-20
AU6654598A (en) 1998-09-08
JP2001521414A (ja) 2001-11-06
JP5105216B2 (ja) 2012-12-26
EP1019027A4 (fr) 2004-05-12
EP1019027A1 (fr) 2000-07-19
WO1998035653A1 (fr) 1998-08-20

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Effective date: 20180212