CA2280966A1 - Materiau implantable de type mastic, a base de collagene - Google Patents

Materiau implantable de type mastic, a base de collagene Download PDF

Info

Publication number
CA2280966A1
CA2280966A1 CA002280966A CA2280966A CA2280966A1 CA 2280966 A1 CA2280966 A1 CA 2280966A1 CA 002280966 A CA002280966 A CA 002280966A CA 2280966 A CA2280966 A CA 2280966A CA 2280966 A1 CA2280966 A1 CA 2280966A1
Authority
CA
Canada
Prior art keywords
acid
collagen
composition
osteogenic
osteoinductive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002280966A
Other languages
English (en)
Other versions
CA2280966C (fr
Inventor
James A. Benedict
Christopher J. Damien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zimmer Orthobiologics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2280966A1 publication Critical patent/CA2280966A1/fr
Application granted granted Critical
Publication of CA2280966C publication Critical patent/CA2280966C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10Polypeptides; Proteins
    • A61L24/102Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention concerne des compositions pour matériau implantable de type mastic, qui permet d'administrer de certains composés actifs à un patient. Plus précisément, l'invention concerne un matériau dont le pH est compris entre environ 3 et 6 et qui possède les propriétés physiques caractéristiques d'un matériau de type mastic, sachant que ledit matériau renferme du collagène et de l'eau. L'invention concerne également un procédé relatif à l'utilisation de ce matériau implantable de type mastic.
CA2280966A 1997-02-13 1998-02-12 Materiau implantable de type mastic, a base de collagene Expired - Lifetime CA2280966C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3707197P 1997-02-13 1997-02-13
US60/037,071 1997-02-13
PCT/US1998/002751 WO1998035653A1 (fr) 1997-02-13 1998-02-12 Materiau implantable de type mastic, a base de collagene

Publications (2)

Publication Number Publication Date
CA2280966A1 true CA2280966A1 (fr) 1998-08-20
CA2280966C CA2280966C (fr) 2012-04-17

Family

ID=21892280

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2280966A Expired - Lifetime CA2280966C (fr) 1997-02-13 1998-02-12 Materiau implantable de type mastic, a base de collagene

Country Status (5)

Country Link
EP (1) EP1019027A4 (fr)
JP (1) JP5105216B2 (fr)
AU (1) AU6654598A (fr)
CA (1) CA2280966C (fr)
WO (1) WO1998035653A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6569172B2 (en) 1996-08-30 2003-05-27 Verigen Transplantation Service International (Vtsi) Method, instruments, and kit for autologous transplantation
US5989269A (en) 1996-08-30 1999-11-23 Vts Holdings L.L.C. Method, instruments and kit for autologous transplantation
US6511958B1 (en) 1997-08-14 2003-01-28 Sulzer Biologics, Inc. Compositions for regeneration and repair of cartilage lesions
EP0896825B1 (fr) 1997-08-14 2002-07-17 Sulzer Innotec Ag Composition et dispositif pour la réparation de cartilage in vivo comprenant des nanocapsules avec des facteurs ostéoinductifs et/ou chondroinductifs
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
NZ526523A (en) 1998-08-14 2004-10-29 Verigen Transplantation Serv An element for use in chondrocyte cell transplatation
EP1161257A2 (fr) 1999-03-17 2001-12-12 Novartis AG Compositions pharmaceutiques
US6576249B1 (en) * 2000-11-13 2003-06-10 El Gendler Bone putty and method
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7132110B2 (en) * 2001-08-30 2006-11-07 Isotis Orthobiologics, Inc. Tissue repair compositions and methods for their manufacture and use
US6974862B2 (en) 2003-06-20 2005-12-13 Kensey Nash Corporation High density fibrous polymers suitable for implant
US20050020506A1 (en) * 2003-07-25 2005-01-27 Drapeau Susan J. Crosslinked compositions comprising collagen and demineralized bone matrix, methods of making and methods of use
US20050186240A1 (en) 2004-02-23 2005-08-25 Ringeisen Timothy A. Gel suitable for implantation and delivery system
DE102005045671A1 (de) * 2005-09-15 2007-03-29 Ossacur Ag Verwendung eines Kollagens xenogenen Ursprungs
US7824703B2 (en) * 2006-02-01 2010-11-02 Warsaw Orthopedics, Inc. Medical implants with reservoir(s), and materials preparable from same
US7892577B2 (en) * 2006-02-27 2011-02-22 Globus Medical, Inc. Bone graft materials derived from mineralized gelatin
US20070248575A1 (en) * 2006-04-19 2007-10-25 Jerome Connor Bone graft composition
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
EP2222348B1 (fr) * 2007-12-21 2013-07-03 RTI Biologics, Inc. Mastics ostéo-inducteurs et leurs procédés de fabrication et d'utilisation
US8840913B2 (en) 2008-03-27 2014-09-23 Warsaw Orthopedic, Inc. Malleable multi-component implants and materials therefor
JP2013542837A (ja) * 2010-11-15 2013-11-28 ジンマー オーソバイオロジクス,インコーポレイティド 骨空隙充填剤
KR101361810B1 (ko) 2011-12-22 2014-02-12 전북대학교산학협력단 조직공학용 dbp 겔
KR102348476B1 (ko) * 2021-03-02 2022-01-06 한국전통문화대학교산학협력단 천연접착제 및 이의 접착강도 향상방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3471598A (en) * 1966-02-14 1969-10-07 Fmc Corp Method of producing absorbent mats
US3443261A (en) * 1967-09-01 1969-05-13 Fmc Corp Prosthetic structures from microcrystalline collagen
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
US4066083A (en) * 1976-06-03 1978-01-03 Pentapharm A.G. Sterile surgical collagen product
CH645271A5 (de) * 1979-10-08 1984-09-28 Pentapharm Ag Verfahren zur herstellung eines kollagenproduktes fuer medizinische und kosmetische zwecke.
DE2967060D1 (en) * 1979-12-18 1984-07-19 Oscobal Ag Bone replacement material and process for producing a bone replacement material
US4394370A (en) * 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4440750A (en) * 1982-02-12 1984-04-03 Collagen Corporation Osteogenic composition and method
CA1259914A (fr) * 1984-07-06 1989-09-26 Donald G. Wallace Methodes de reparation des os a l'aide de collagene
US4969912A (en) * 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US5475052A (en) * 1988-11-21 1995-12-12 Collagen Corporation Collagen-synthetic polymer matrices prepared using a multiple step reaction
US5707962A (en) * 1994-09-28 1998-01-13 Gensci Regeneration Sciences Inc. Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof

Also Published As

Publication number Publication date
EP1019027A1 (fr) 2000-07-19
CA2280966C (fr) 2012-04-17
JP5105216B2 (ja) 2012-12-26
AU6654598A (en) 1998-09-08
WO1998035653A1 (fr) 1998-08-20
EP1019027A4 (fr) 2004-05-12
JP2001521414A (ja) 2001-11-06

Similar Documents

Publication Publication Date Title
CA2280966A1 (fr) Materiau implantable de type mastic, a base de collagene
US5409896A (en) TGF-β composition for inducing bone growth
TW318792B (fr)
AU671721B2 (en) Tgf-beta formulation for inducing bone growth
US8690874B2 (en) Composition and process for bone growth and repair
Panduranga Rao Recent developments of collagen-based materials for medical applications and drug delivery systems
US5422340A (en) TGF-βformulation for inducing bone growth
US5246457A (en) Xenogeneic collagen/mineral preparations in bone repair
US6679918B1 (en) Implantable putty material
US7883693B2 (en) Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
JP3727059B2 (ja) 多孔質複合材料の製造方法
US8497236B2 (en) Implantable putty material
CA1328151C (fr) Implantation de protheses
JPH07171211A (ja) 線維芽細胞成長因子を装入した骨代替材料
IE53579B1 (en) Collagen implant containing active ingredient(s)for implantation in bones or soft tissues and process for its manufacture
US20100272693A1 (en) Bone scaffolds, injectable bone repair materials and methods for bone repair
JPS6162466A (ja) コラ−ゲン被覆骨移植片
EP0243178B1 (fr) Matrice moelle/collagène/composé minéral pour la réparation des défauts osseux
WO2001070288A2 (fr) Polymeres thermoreversibles pour le transport ou la retention de proteines osteo-inductives
JP3424049B2 (ja) 骨形成用移植体
Yamazaki et al. Ectopic induction of cartilage and bone by bovine bone morphogenetic protein using a biodegradable polymeric reservoir
EP0585168A2 (fr) Composition et méthode pour la génération d'os
EP1844798A1 (fr) Matériel avec mastic implantable
Geiger Porous Collagen/Ceramic Composite Carriers for Bone Regeneration Using Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2)
CA1310918C (fr) Irradiation gamma de melanges collagenes/mineraux

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20180212