CA2273288A1 - Method of treating or inhibiting neutropenia - Google Patents

Method of treating or inhibiting neutropenia Download PDF

Info

Publication number
CA2273288A1
CA2273288A1 CA002273288A CA2273288A CA2273288A1 CA 2273288 A1 CA2273288 A1 CA 2273288A1 CA 002273288 A CA002273288 A CA 002273288A CA 2273288 A CA2273288 A CA 2273288A CA 2273288 A1 CA2273288 A1 CA 2273288A1
Authority
CA
Canada
Prior art keywords
carbon atoms
alkyl
phenyl
trifluoromethyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002273288A
Other languages
English (en)
French (fr)
Inventor
James Joseph Gibbons
Judy Lucas
Jeremy Ian Levin
Joseph William Epstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2273288A1 publication Critical patent/CA2273288A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002273288A 1996-12-19 1997-12-17 Method of treating or inhibiting neutropenia Abandoned CA2273288A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77074396A 1996-12-19 1996-12-19
US08/770,743 1996-12-19
PCT/US1997/023419 WO1998026781A1 (en) 1996-12-19 1997-12-17 Method of treating or inhibiting neutropenia

Publications (1)

Publication Number Publication Date
CA2273288A1 true CA2273288A1 (en) 1998-06-25

Family

ID=25089545

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002273288A Abandoned CA2273288A1 (en) 1996-12-19 1997-12-17 Method of treating or inhibiting neutropenia

Country Status (7)

Country Link
EP (1) EP0957918A1 (xx)
JP (1) JP2001506998A (xx)
AR (1) AR010808A1 (xx)
AU (1) AU5611398A (xx)
CA (1) CA2273288A1 (xx)
WO (1) WO1998026781A1 (xx)
ZA (1) ZA9711342B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11116738B2 (en) 2012-06-07 2021-09-14 Children's Hospital Los Angeles Methods for treating neutropenia using retinoid agonists
US10286039B2 (en) 2014-02-18 2019-05-14 Children's Hospital Los Angeles Compositions and methods for treating neutropenia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2615291B1 (fr) * 1987-05-15 1989-07-13 Thomson Csf Procede de test en fonctionnement d'un dispositif de visualisation d'informations radar et mise en oeuvre de ce procede
US4916137A (en) * 1988-02-22 1990-04-10 American Cyanamid Company 5-(Substituted-amino)-8-(phenyl or substituted-phenyl)-3H,6H-1,4,5A,8A-tetraazaacenaphthylen-3-ones and treatment of neural behavior disorders
ATE99686T1 (de) * 1988-02-22 1994-01-15 American Cyanamid Co 5-(substituierte amino)-8-(phenyl oder substituierte phenyl)-3h,6h-1,4,5a,8atetraazaacenaphthylen-3-one.

Also Published As

Publication number Publication date
AU5611398A (en) 1998-07-15
WO1998026781A1 (en) 1998-06-25
AR010808A1 (es) 2000-07-12
JP2001506998A (ja) 2001-05-29
EP0957918A1 (en) 1999-11-24
ZA9711342B (en) 1999-06-17

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Legal Events

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FZDE Dead