CA2266319C - Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof - Google Patents
Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof Download PDFInfo
- Publication number
- CA2266319C CA2266319C CA002266319A CA2266319A CA2266319C CA 2266319 C CA2266319 C CA 2266319C CA 002266319 A CA002266319 A CA 002266319A CA 2266319 A CA2266319 A CA 2266319A CA 2266319 C CA2266319 C CA 2266319C
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- nucleic acid
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- acid molecule
- isolated nucleic
- protein encoded
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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Landscapes
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/725,182 US5804381A (en) | 1996-10-03 | 1996-10-03 | Isolated nucleic acid molecule encoding an esophageal cancer associated antigen, the antigen itself, and uses thereof |
| US08/725,182 | 1996-10-03 | ||
| PCT/US1997/016335 WO1998014464A1 (en) | 1996-10-03 | 1997-09-15 | Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2266319A1 CA2266319A1 (en) | 1998-04-09 |
| CA2266319C true CA2266319C (en) | 2005-12-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002266319A Expired - Lifetime CA2266319C (en) | 1996-10-03 | 1997-09-15 | Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US5804381A (enExample) |
| EP (1) | EP0948518B1 (enExample) |
| JP (1) | JP3799483B2 (enExample) |
| KR (1) | KR20000048851A (enExample) |
| CN (1) | CN1283652C (enExample) |
| AT (1) | ATE260930T1 (enExample) |
| AU (1) | AU732068B2 (enExample) |
| CA (1) | CA2266319C (enExample) |
| DE (1) | DE69727966T2 (enExample) |
| DK (1) | DK0948518T3 (enExample) |
| ES (1) | ES2216169T3 (enExample) |
| NZ (1) | NZ335485A (enExample) |
| PT (1) | PT948518E (enExample) |
| WO (1) | WO1998014464A1 (enExample) |
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| US6252052B1 (en) * | 1996-10-03 | 2001-06-26 | Cornell Research Foundation, Inc | Antibodies which bind to NY-ESO-1 cancer associated proteins, and hybridomas which produce these antibodies |
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| US6417165B1 (en) | 1988-03-27 | 2002-07-09 | Ludwig Institute For Cancer Research | NY-ESO-1-peptide derivatives, and uses thereof |
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| US7888100B2 (en) * | 1996-10-03 | 2011-02-15 | Memorial Sloan-Kettering Cancer Research | Isolated nucleic acid molecules which encode immunogenic portions of NY-ESO-1 protein |
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| DE69837273T2 (de) * | 1997-10-08 | 2008-01-31 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Menschliches krebsantigen ny eso-1/cag-3 und dazu kodierendes gen |
| US7084239B1 (en) | 1997-10-08 | 2006-08-01 | The United States Of America As Represented By The Department Of Health And Human Services | Cancer peptides of NY-ESO-1/CAG-3 |
| EP1806403A3 (en) * | 1997-10-08 | 2008-01-23 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Human cancer antigen NY ESO 1/CAG-3 and gene encoding same |
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| US6140050A (en) * | 1998-06-26 | 2000-10-31 | Ludwig Institute For Cancer Research | Methods for determining breast cancer and melanoma by assaying for a plurality of antigens associated therewith |
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| WO2000050595A2 (en) * | 1999-02-25 | 2000-08-31 | Ivan Gout | Nucleic acid molecules associated with melanoma and thyroid tumors |
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| US6689742B1 (en) * | 2000-02-25 | 2004-02-10 | Chancellors, Masters And Scholars Of The University Of Oxford | NY-ESO-1 peptide derivatives, and uses thereof |
| US20020001805A1 (en) * | 2000-03-14 | 2002-01-03 | Roden Richard Bruce | Immunogenic ovarian cancer genes |
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| JP5283335B2 (ja) * | 2003-06-17 | 2013-09-04 | マンカインド コーポレイション | 各種癌の治療を目的とした腫瘍関連抗原の組合せ |
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| DE10347710B4 (de) | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| WO2005114203A2 (en) * | 2004-05-20 | 2005-12-01 | The Regents Of The University Of California | Dominant b cell epitopes and methods of making and using thereof |
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| PL1833506T3 (pl) | 2004-12-29 | 2016-01-29 | Mannkind Corp | Zastosowanie kompozycji zawierających różne antygeny związane z nowotworem jako szczepionek przeciwnowotworowych |
| KR101294290B1 (ko) * | 2004-12-29 | 2013-08-07 | 맨카인드 코포레이션 | 예방 또는 치료를 위해 제ｉ류 주조직 적합성복합체〔ｍｈｃ〕-제한 에피토프에 대한 면역 반응을 유발,향상 및 지속하는 방법 |
| NZ564360A (en) | 2005-06-17 | 2011-03-31 | Mannkind Corp | Immunogenic product comprising a nucleic acid capable of expressing a PRAME epitope and a PSMA epitope and a peptide composition |
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| JP5416968B2 (ja) | 2005-06-17 | 2014-02-12 | マンカインド コーポレイション | 癌細胞及び腫瘍間質上に発現される優勢及び亜優勢エピトープに対する多価免疫応答を誘発するための方法及び組成物 |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| US8309096B2 (en) * | 2007-01-15 | 2012-11-13 | Glaxosmithkline Biologicals S.A. | Fusion protein |
| WO2009046738A1 (en) | 2007-10-09 | 2009-04-16 | Curevac Gmbh | Composition for treating lung cancer, particularly of non-small lung cancers (nsclc) |
| CA2704583A1 (en) | 2007-11-07 | 2009-05-14 | Celldex Therapeutics Inc. | Antibodies that bind human dendritic and epithelial cell 205 receptor(dec-205) |
| US8815564B2 (en) | 2008-03-14 | 2014-08-26 | Sanofi Pasteur Biologics, Llc | Replication-defective flavivirus vaccines and vaccine vectors |
| BRPI1009873A2 (pt) | 2009-03-17 | 2016-03-08 | Glaxosmithkline Biolog Sa | detecção aperfeiçoada de expressão gênica |
| GB0910046D0 (en) | 2009-06-10 | 2009-07-22 | Glaxosmithkline Biolog Sa | Novel compositions |
| BR112012026227A2 (pt) | 2010-04-13 | 2020-08-04 | Celldex Therapeutics, Inc. | anticorpo monoclonal humano ou humanizado, molécula biespecífica, vetor de expressão, célula transformada, composição, e, usos de um anticorpo |
| HRP20230443T1 (hr) | 2011-05-24 | 2023-09-15 | BioNTech SE | Individualizirana cjepiva protiv raka |
| GB201116248D0 (en) | 2011-09-20 | 2011-11-02 | Glaxosmithkline Biolog Sa | Liposome production using isopropanol |
| US8490054B2 (en) | 2011-09-23 | 2013-07-16 | The United States Of America As Represented By The Secretary Of The Army | Software and related software tracking during software modification |
| NL2007536C2 (en) | 2011-10-05 | 2013-04-08 | Academisch Ziekenhuis Leiden Lumc | Adjuvant compound. |
| WO2013143555A1 (en) | 2012-03-26 | 2013-10-03 | Biontech Ag | Rna formulation for immunotherapy |
| WO2014074785A1 (en) | 2012-11-08 | 2014-05-15 | Ludwig Institute For Cancer Research Ltd. | Methods of predicting outcome and treating breast cancer |
| AU2013351542B2 (en) | 2012-11-28 | 2018-08-09 | BioNTech SE | Individualized vaccines for cancer |
| WO2014140938A2 (en) | 2013-03-14 | 2014-09-18 | Centre Hospitalier Universitaire Vaudois | Immunological methods |
| WO2014180490A1 (en) | 2013-05-10 | 2014-11-13 | Biontech Ag | Predicting immunogenicity of t cell epitopes |
| AU2015271709B2 (en) | 2014-06-06 | 2020-11-26 | Bristol-Myers Squibb Company | Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof |
| WO2016040682A1 (en) | 2014-09-10 | 2016-03-17 | Genentech, Inc. | Immunogenic mutant peptide screening platform |
| WO2016045732A1 (en) | 2014-09-25 | 2016-03-31 | Biontech Rna Pharmaceuticals Gmbh | Stable formulations of lipids and liposomes |
| WO2016128060A1 (en) | 2015-02-12 | 2016-08-18 | Biontech Ag | Predicting t cell epitopes useful for vaccination |
| US20180044429A1 (en) | 2015-03-09 | 2018-02-15 | Celldex Therapeutics, Inc. | Cd27 agonists |
| MX2017015041A (es) | 2015-05-29 | 2018-02-26 | Squibb Bristol Myers Co | Anticuerpos contra el miembro 4 de la superfamilia del receptor del factor de necrosis tumoral (ox40) y sus usos. |
| WO2017059902A1 (en) | 2015-10-07 | 2017-04-13 | Biontech Rna Pharmaceuticals Gmbh | 3' utr sequences for stabilization of rna |
| JP6983776B2 (ja) | 2015-11-19 | 2021-12-17 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | グルココルチコイド誘発腫瘍壊死因子受容体（ｇｉｔｒ）に対する抗体およびその使用 |
| CN109071665B (zh) | 2016-04-18 | 2022-11-01 | 塞德斯医疗公司 | 结合人cd40的激动性抗体及其用途 |
| NL2018803B1 (en) | 2017-04-27 | 2018-11-05 | Academisch Ziekenhuis Leiden Handelend Onder De Naam Leids Univ Medisch Centrum/ H O D N Lumc | Adjuvant compounds |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| WO2021116462A1 (en) | 2019-12-11 | 2021-06-17 | Molecular Partners Ag | Designed ankyrin repeat domains with altered surface residues |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4772547A (en) * | 1986-02-03 | 1988-09-20 | Hoffmann-La Roche Inc. | HTLV-III envelope peptides |
| US5057540A (en) * | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US5212085A (en) * | 1987-12-09 | 1993-05-18 | The General Hospital Corporation | Sf-25 colon adenocarcinoma antigen, and antibodies with recognize this antigen |
| US5858689A (en) * | 1993-07-22 | 1999-01-12 | Ludwig Institute For Cancer Research | Isolated peptides derived from the gage tumor rejection antigen precursor and uses thereof |
| US5709995A (en) * | 1994-03-17 | 1998-01-20 | The Scripps Research Institute | Hepatitis C virus-derived peptides capable of inducing cytotoxic T lymphocyte responses |
| US5830753A (en) * | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
| DE69837273T2 (de) | 1997-10-08 | 2008-01-31 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Menschliches krebsantigen ny eso-1/cag-3 und dazu kodierendes gen |
-
1996
- 1996-10-03 US US08/725,182 patent/US5804381A/en not_active Expired - Lifetime
-
1997
- 1997-09-15 JP JP51656798A patent/JP3799483B2/ja not_active Expired - Lifetime
- 1997-09-15 DE DE69727966T patent/DE69727966T2/de not_active Expired - Lifetime
- 1997-09-15 WO PCT/US1997/016335 patent/WO1998014464A1/en not_active Ceased
- 1997-09-15 DK DK97941626T patent/DK0948518T3/da active
- 1997-09-15 ES ES97941626T patent/ES2216169T3/es not_active Expired - Lifetime
- 1997-09-15 KR KR1019990702853A patent/KR20000048851A/ko not_active Ceased
- 1997-09-15 CA CA002266319A patent/CA2266319C/en not_active Expired - Lifetime
- 1997-09-15 PT PT97941626T patent/PT948518E/pt unknown
- 1997-09-15 CN CNB971985383A patent/CN1283652C/zh not_active Expired - Lifetime
- 1997-09-15 US US08/937,263 patent/US6274145B1/en not_active Expired - Lifetime
- 1997-09-15 NZ NZ335485A patent/NZ335485A/xx not_active IP Right Cessation
- 1997-09-15 AU AU43495/97A patent/AU732068B2/en not_active Expired
- 1997-09-15 EP EP97941626A patent/EP0948518B1/en not_active Expired - Lifetime
- 1997-09-15 AT AT97941626T patent/ATE260930T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0948518B1 (en) | 2004-03-03 |
| ES2216169T3 (es) | 2004-10-16 |
| WO1998014464A1 (en) | 1998-04-09 |
| DK0948518T3 (da) | 2004-07-05 |
| JP2001507212A (ja) | 2001-06-05 |
| EP0948518A4 (en) | 2002-01-02 |
| AU732068B2 (en) | 2001-04-12 |
| JP3799483B2 (ja) | 2006-07-19 |
| NZ335485A (en) | 2001-01-26 |
| CN1283652C (zh) | 2006-11-08 |
| US5804381A (en) | 1998-09-08 |
| CA2266319A1 (en) | 1998-04-09 |
| US6274145B1 (en) | 2001-08-14 |
| ATE260930T1 (de) | 2004-03-15 |
| DE69727966T2 (de) | 2005-02-10 |
| KR20000048851A (ko) | 2000-07-25 |
| HK1020968A1 (en) | 2000-05-26 |
| EP0948518A1 (en) | 1999-10-13 |
| PT948518E (pt) | 2004-06-30 |
| CN1232467A (zh) | 1999-10-20 |
| AU4349597A (en) | 1998-04-24 |
| DE69727966D1 (de) | 2004-04-08 |
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| MKEX | Expiry |
Effective date: 20170915 |