CA2261808A1 - Derives de 1-azoniabicyclo¬2.2.1|heptane et compositions pharmaceutiques les contenant - Google Patents

Derives de 1-azoniabicyclo¬2.2.1|heptane et compositions pharmaceutiques les contenant Download PDF

Info

Publication number
CA2261808A1
CA2261808A1 CA002261808A CA2261808A CA2261808A1 CA 2261808 A1 CA2261808 A1 CA 2261808A1 CA 002261808 A CA002261808 A CA 002261808A CA 2261808 A CA2261808 A CA 2261808A CA 2261808 A1 CA2261808 A1 CA 2261808A1
Authority
CA
Canada
Prior art keywords
formula
unsubstituted
compound
alkyl
monosubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002261808A
Other languages
English (en)
Inventor
Didier Van Broeck
Xavier Emonds-Alt
Joelle Taillades
Patrick Gueule
Vincenzo Proietto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2261808A1 publication Critical patent/CA2261808A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention a pour objet un composé de formule (I) dans laquelle: A représente un radical bivalent choisi parmi: A¿1?)-O-CO-; A¿2?)-CH¿2?-O-CO-; A¿3?)-O-CH¿2?-CO-; A¿4?)-O-CH¿2?-CH¿2?-; A¿5?)-N(R¿1?)-CO-; A¿6?)-N(R¿1?)-CO-CO-; A¿7?)-N(R¿1?)-CH¿2?-CH¿2?-; A¿8?)-O-CH¿2?-; dans lesquels R¿1? représente un hydrogène ou un (C¿1?-C¿4?)alkyle; Am représente (1). Application: antagonistes des récepteurs des neurokinines.
CA002261808A 1996-07-26 1997-07-25 Derives de 1-azoniabicyclo¬2.2.1|heptane et compositions pharmaceutiques les contenant Abandoned CA2261808A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9609439A FR2751654B1 (fr) 1996-07-26 1996-07-26 Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
FR9609439 1996-07-26
PCT/FR1997/001393 WO1998004561A1 (fr) 1996-07-26 1997-07-25 Derives de 1-azoniabicyclo[2.2.1]heptane et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
CA2261808A1 true CA2261808A1 (fr) 1998-02-05

Family

ID=9494521

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002261808A Abandoned CA2261808A1 (fr) 1996-07-26 1997-07-25 Derives de 1-azoniabicyclo¬2.2.1|heptane et compositions pharmaceutiques les contenant

Country Status (8)

Country Link
EP (1) EP0915882A1 (fr)
JP (1) JP2000515878A (fr)
AU (1) AU3854597A (fr)
BR (1) BR9710517A (fr)
CA (1) CA2261808A1 (fr)
FR (1) FR2751654B1 (fr)
NO (1) NO312244B1 (fr)
WO (1) WO1998004561A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2873373B1 (fr) 2004-07-23 2006-09-08 Sanofi Synthelabo Derives de 4-arylmorpholin-3-one, leur preparation et leur application en therapeutique
EP2117538A1 (fr) 2007-01-24 2009-11-18 Glaxo Group Limited Compositions pharmaceutiques contenant du 2-méthoxy-5- (5-trifluorométhyl-tétrazol-i-yl-benzyl) - (2s-phényl-pipéridin-3s-yl-)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2696178B1 (fr) * 1992-09-30 1994-12-30 Sanofi Elf Amides basiques quaternaires, procédé pour leur préparation et compositions pharmaceutiques en contenant.
FR2729954B1 (fr) * 1995-01-30 1997-08-01 Sanofi Sa Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
FR2751654A1 (fr) 1998-01-30
JP2000515878A (ja) 2000-11-28
BR9710517A (pt) 1999-08-17
NO990278D0 (no) 1999-01-22
NO990278L (no) 1999-01-22
WO1998004561A1 (fr) 1998-02-05
FR2751654B1 (fr) 1998-10-23
NO312244B1 (no) 2002-04-15
AU3854597A (en) 1998-02-20
EP0915882A1 (fr) 1999-05-19

Similar Documents

Publication Publication Date Title
RU2157807C2 (ru) Замещенные гетероциклические соединения, способ их получения и фармацевтическая композиция
US5780466A (en) Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present
KR100238343B1 (ko) 인간 nk3 수용기의 선택적 길항제인 화합물, 및 의약품 및 진단기구로서의 그의 용도
RU2083574C1 (ru) Полициклические аминосодержащие соединения или их соли, их оптически чистые изомеры, способ получения полициклических аминосодержащих соединений, циклические аминосодержащие соединения или их соли, их оптически чистые изомеры и фармацевтическая композиция, обладающая антагонистической активностью к рецепторам нейрокинина
FR2738245A1 (fr) Nouveaux derives de piperidine, procede pour leur obtention et compositions pharmaceutiques les contenant
HUT73226A (en) With arylaliphatic and alkyl-groups n-substituted novel amides, method for their preparation and pharmaceutical compositions containing same
MXPA03010133A (es) Nuevos derivados de piperidinacarboxamida, un procedimiento para su preparacion y las composiciones farmaceuticas que los contienen.
BG64623B1 (bg) Нови морфолинови производни, метод за тяхното получаване и фармацевтични състави, които ги съдържат
CA2261808A1 (fr) Derives de 1-azoniabicyclo¬2.2.1|heptane et compositions pharmaceutiques les contenant
KR100477164B1 (ko) 치환된 헤테로 고리 화합물, 그의 제조 방법 및 그를함유하는 제약학적 조성물
AU731788B2 (en) Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same
FR2729952A1 (fr) Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
MXPA99000736A (en) 1-azoniabicyclo[2.2.1]heptane derivatives and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
FZDE Dead