CA2259493A1 - Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides - Google Patents

Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides Download PDF

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Publication number
CA2259493A1
CA2259493A1 CA 2259493 CA2259493A CA2259493A1 CA 2259493 A1 CA2259493 A1 CA 2259493A1 CA 2259493 CA2259493 CA 2259493 CA 2259493 A CA2259493 A CA 2259493A CA 2259493 A1 CA2259493 A1 CA 2259493A1
Authority
CA
Canada
Prior art keywords
species
metal ion
coordinate
moiety
strand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2259493
Other languages
English (en)
French (fr)
Inventor
Changhee Min
Gregory L. Verdine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard College
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2259493A1 publication Critical patent/CA2259493A1/en
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Composite Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
CA 2259493 1996-07-03 1997-06-30 Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides Abandoned CA2259493A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2119596P 1996-07-03 1996-07-03
US60/021,195 1996-07-03

Publications (1)

Publication Number Publication Date
CA2259493A1 true CA2259493A1 (en) 1998-01-08

Family

ID=21802886

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2259493 Abandoned CA2259493A1 (en) 1996-07-03 1997-06-30 Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides

Country Status (5)

Country Link
EP (1) EP0917533A2 (ja)
JP (1) JP2000514799A (ja)
AU (1) AU739391B2 (ja)
CA (1) CA2259493A1 (ja)
WO (1) WO1998000435A2 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP856399A0 (en) * 1999-02-08 1999-03-04 Australian Membrane And Biotechnology Research Institute Improved compounds for protein binding
EP1212458A4 (en) * 1999-07-30 2005-01-05 Surromed Inc INSTRUMENTS, METHODS AND REAGENTS FOR PLASMON SURFACE RESONANCE
AU2002241515A1 (en) 2000-11-06 2002-06-18 The University Of Houston System Nucleic acid separation using immobilized metal affinity chromatography
AU2003222676B2 (en) 2002-05-10 2009-04-23 Anteo Technologies Pty Ltd Generation of surface coating diversity
SE0203521D0 (sv) * 2002-11-28 2002-11-28 Amersham Biosciences Ab Isolation of antisense oligonucleotides
US7893222B2 (en) * 2002-12-20 2011-02-22 University Of Houston Introduction of structural affinity handles as a tool in selective nucleic acid separations
US7371852B2 (en) * 2003-01-22 2008-05-13 Serenex, Inc. Alkyl-linked nucleotide compositions
JP4783149B2 (ja) * 2003-09-02 2011-09-28 独立行政法人科学技術振興機構 金属錯体型核酸
US8168445B2 (en) 2004-07-02 2012-05-01 Bio-Layer Pty Limited Use of metal complexes
WO2008134472A1 (en) * 2007-04-25 2008-11-06 3M Innovative Properties Company Compositions, methods, and devices for isolating biological materials

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US5175269A (en) * 1984-01-30 1992-12-29 Enzo Diagnostics, Inc. Compound and detectable molecules having an oligo- or polynucleotide with modifiable reactive group
US4952685A (en) * 1984-01-30 1990-08-28 Enzo Biochem, Inc. Detectable molecules, method of preparation and use
US5221605A (en) * 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
JP2509574B2 (ja) * 1985-08-15 1996-06-19 アモコ・コーポレーション 標識付けした核酸
SE454781B (sv) * 1986-10-17 1988-05-30 Wallac Oy Hybridiseringsforfarande for detektion av polynukleotidsekvens
US4962045A (en) * 1988-05-02 1990-10-09 The Perkin-Elmer Corporation Time-resolved fluorimetric detection of lanthanide labeled nucleotides
SE8802574D0 (sv) * 1988-07-08 1988-07-08 Wallac Oy Oligonucleotide hybridization probes and means for the synthesis of the most preferred probes
US5250188A (en) * 1989-09-01 1993-10-05 Brigham Young University Process of removing and concentrating desired molecules from solutions
US5294369A (en) * 1990-12-05 1994-03-15 Akzo N.V. Ligand gold bonding
US5439829A (en) * 1991-01-30 1995-08-08 Eli Lilly And Company Immobilization of biologically active molecules by changing the Oxidation state of a chelated transition metal ion
ES2108109T3 (es) * 1991-02-14 1997-12-16 Dade Microscan Inc Nuevos oligonucleotidos conjugados con quelatos de lantanidos.
EP0519250A3 (en) * 1991-06-10 1993-06-02 Miles Inc. Microparticle-labeled binding assay analyzed by microwave spectroscopy
GB2284208A (en) * 1993-11-25 1995-05-31 Pna Diagnostics As Nucleic acid analogues with a chelating functionality for metal ions
IL114237A (en) * 1994-07-14 2000-08-31 Schering Ag Oligonucleotide conjugates and diagnostic processes utilizing the same
PT778844E (pt) * 1994-09-02 2003-04-30 Novartis Ag Complexos funcionais de metais de terpiridina processos para a sua preparacao e conjugados oligonucleotideos com complexos de metais de terpiridina
US5620850A (en) * 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers

Also Published As

Publication number Publication date
JP2000514799A (ja) 2000-11-07
AU739391B2 (en) 2001-10-11
AU4038997A (en) 1998-01-21
WO1998000435A2 (en) 1998-01-08
EP0917533A2 (en) 1999-05-26
WO1998000435A3 (en) 1998-05-07

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