CA2258512C - Amidases, nucleic acids encoding them and methods for making and using them - Google Patents

Amidases, nucleic acids encoding them and methods for making and using them Download PDF

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Publication number
CA2258512C
CA2258512C CA002258512A CA2258512A CA2258512C CA 2258512 C CA2258512 C CA 2258512C CA 002258512 A CA002258512 A CA 002258512A CA 2258512 A CA2258512 A CA 2258512A CA 2258512 C CA2258512 C CA 2258512C
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CA
Canada
Prior art keywords
seq
polynucleotide
sequence
enzyme
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002258512A
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English (en)
French (fr)
Other versions
CA2258512A1 (en
Inventor
Dennis Murphy
John C. Reid
Dan Robertson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Enzymes LLC
Original Assignee
Verenium Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verenium Corp filed Critical Verenium Corp
Publication of CA2258512A1 publication Critical patent/CA2258512A1/en
Application granted granted Critical
Publication of CA2258512C publication Critical patent/CA2258512C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Peptides Or Proteins (AREA)
CA002258512A 1996-06-17 1997-06-17 Amidases, nucleic acids encoding them and methods for making and using them Expired - Fee Related CA2258512C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/664,646 US5877001A (en) 1996-06-17 1996-06-17 Amidase
US08/664,646 1996-06-17
PCT/US1997/009319 WO1997048794A1 (en) 1996-06-17 1997-06-17 Amidase

Publications (2)

Publication Number Publication Date
CA2258512A1 CA2258512A1 (en) 1997-12-24
CA2258512C true CA2258512C (en) 2009-01-20

Family

ID=24666850

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002258512A Expired - Fee Related CA2258512C (en) 1996-06-17 1997-06-17 Amidases, nucleic acids encoding them and methods for making and using them

Country Status (9)

Country Link
US (8) US5877001A (enExample)
EP (1) EP0937139B1 (enExample)
JP (1) JP4306802B2 (enExample)
AT (1) ATE275205T1 (enExample)
AU (1) AU723433B2 (enExample)
CA (1) CA2258512C (enExample)
DE (1) DE69730514T2 (enExample)
ES (1) ES2227701T3 (enExample)
WO (1) WO1997048794A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103382464A (zh) * 2013-07-22 2013-11-06 上海交通大学 来源于超嗜热古菌的酰胺酶及其编码基因与应用

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US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5877001A (en) * 1996-06-17 1999-03-02 Diverso Corporation Amidase
US20020137185A1 (en) * 1996-06-17 2002-09-26 Jay Short Enzymes having amidase activity and methods of use thereof
US7148054B2 (en) 1997-01-17 2006-12-12 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
WO1998031837A1 (en) 1997-01-17 1998-07-23 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6723550B1 (en) * 1997-07-15 2004-04-20 Genencor International, Inc. Proteases from gram-positive organisms
US6153352A (en) * 1997-12-10 2000-11-28 Fuji Photo Film Co., Ltd. Planographic printing plate precursor and a method for producing a planographic printing plate
US6541011B2 (en) 1998-02-11 2003-04-01 Maxygen, Inc. Antigen library immunization
US7390619B1 (en) * 1998-02-11 2008-06-24 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
CA2325567A1 (en) 1998-05-01 1999-11-11 Maxygen, Inc. Optimization of pest resistance genes using dna shuffling
US7153655B2 (en) * 1998-06-16 2006-12-26 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
US6605430B1 (en) 1998-08-12 2003-08-12 Maxygen, Inc. DNA shuffling of monooxygenase genes for production of industrial chemicals
US20060242731A1 (en) * 1998-08-12 2006-10-26 Venkiteswaran Subramanian DNA shuffling to produce herbicide selective crops
AU6510799A (en) 1998-10-07 2000-04-26 Maxygen, Inc. Dna shuffling to produce nucleic acids for mycotoxin detoxification
WO2000028018A1 (en) 1998-11-10 2000-05-18 Maxygen, Inc. Modified adp-glucose pyrophosphorylase for improvement and optimization of plant phenotypes
US6438561B1 (en) * 1998-11-19 2002-08-20 Navigation Technologies Corp. Method and system for using real-time traffic broadcasts with navigation systems
WO2000042559A1 (en) * 1999-01-18 2000-07-20 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US20030054390A1 (en) * 1999-01-19 2003-03-20 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6917882B2 (en) 1999-01-19 2005-07-12 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6961664B2 (en) 1999-01-19 2005-11-01 Maxygen Methods of populating data structures for use in evolutionary simulations
US20070065838A1 (en) * 1999-01-19 2007-03-22 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US7024312B1 (en) * 1999-01-19 2006-04-04 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
JP2002534965A (ja) 1999-01-19 2002-10-22 マキシジェン， インコーポレイテッド 所望の特徴を有する文字ストリング、ポリヌクレオチドおよびポリペプチドを作製するための方法
KR20010102069A (ko) 1999-02-11 2001-11-15 추후제출 고효율 질량 분석
JP3399518B2 (ja) * 1999-03-03 2003-04-21 インターナショナル・ビジネス・マシーンズ・コーポレーション 半導体構造およびその製造方法
EP1165757A1 (en) 1999-03-05 2002-01-02 Maxygen, Inc. Encryption of traits using split gene sequences
US6531316B1 (en) 1999-03-05 2003-03-11 Maxyag, Inc. Encryption of traits using split gene sequences and engineered genetic elements
AU5805500A (en) * 1999-07-07 2001-01-30 Maxygen Aps A method for preparing modified polypeptides
US20040002474A1 (en) * 1999-10-07 2004-01-01 Maxygen Inc. IFN-alpha homologues
US7430477B2 (en) 1999-10-12 2008-09-30 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US6686515B1 (en) 1999-11-23 2004-02-03 Maxygen, Inc. Homologous recombination in plants
US7115712B1 (en) 1999-12-02 2006-10-03 Maxygen, Inc. Cytokine polypeptides
CN1301735A (zh) * 1999-12-24 2001-07-04 上海博德基因开发有限公司 一种新的多肽——酰胺酶家族蛋白10和编码这种多肽的多核苷酸
JP2003519495A (ja) 2000-01-11 2003-06-24 マキシジェン， インコーポレイテッド 多様性生成およびスクリーニングのための一体化されたシステムおよび方法
AU2001241939A1 (en) * 2000-02-28 2001-09-12 Maxygen, Inc. Single-stranded nucleic acid template-mediated recombination and nucleic acid fragment isolation
WO2001073000A2 (en) * 2000-03-24 2001-10-04 Maxygen, Inc. Methods for modulating cellular and organismal phenotypes
EP1360290A2 (en) 2000-06-23 2003-11-12 Maxygen, Inc. Co-stimulatory molecules
EP1297146A2 (en) 2000-06-23 2003-04-02 Maxygen, Inc. Novel chimeric promoters
US20020072097A1 (en) * 2000-07-07 2002-06-13 Delcardayre Stephen Molecular breeding of transposable elements
US6858422B2 (en) 2000-07-13 2005-02-22 Codexis, Inc. Lipase genes
WO2002010750A2 (en) * 2000-07-31 2002-02-07 Maxygen, Inc. Biosensors, reagents and diagnostic applications of directed evolution
WO2002016583A2 (en) * 2000-08-24 2002-02-28 Maxygen, Inc. Constructs and their use in metabolic pathway engineering
US6958213B2 (en) 2000-12-12 2005-10-25 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function
US20020086292A1 (en) 2000-12-22 2002-07-04 Shigeaki Harayama Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules
US7977073B2 (en) 2001-08-28 2011-07-12 Mitsubishi Rayon Co., Ltd. Polynucleotide encoding a thermostable amide hydrolase and methods for producing an L-α-amino acid
WO2003097834A2 (en) * 2002-05-17 2003-11-27 Alligator Bioscience Ab A method for in vitro molecular evolution of protein function
WO2006069129A1 (en) * 2004-12-22 2006-06-29 E.I. Dupont De Nemours And Company Method for the production of glycolic acid from ammonium glycolate by direct deammoniation
GB2432366B (en) * 2005-11-19 2007-11-21 Alligator Bioscience Ab A method for in vitro molecular evolution of protein function
WO2019044916A1 (ja) * 2017-08-30 2019-03-07 国立大学法人 東京大学 薬剤担持薄膜

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4014564C1 (enExample) * 1990-05-07 1991-07-18 Forschungszentrum Juelich Gmbh, 5170 Juelich, De
CA2119188A1 (en) * 1993-04-05 1994-10-06 Patricia A. Spears Detection and identification of mycobacteria
US5451522A (en) * 1994-07-15 1995-09-19 Eli Lilly And Company Genes encoding and method of expressing an enzyme: phthalyl amidase
US5877001A (en) * 1996-06-17 1999-03-02 Diverso Corporation Amidase

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103382464A (zh) * 2013-07-22 2013-11-06 上海交通大学 来源于超嗜热古菌的酰胺酶及其编码基因与应用
CN103382464B (zh) * 2013-07-22 2015-12-23 上海交通大学 来源于超嗜热古菌的酰胺酶及其编码基因与应用

Also Published As

Publication number Publication date
WO1997048794A1 (en) 1997-12-24
US6465204B1 (en) 2002-10-15
CA2258512A1 (en) 1997-12-24
US5985646A (en) 1999-11-16
ATE275205T1 (de) 2004-09-15
EP0937139A4 (en) 2000-08-02
US6525190B1 (en) 2003-02-25
US6004796A (en) 1999-12-21
DE69730514T2 (de) 2005-09-01
JP4306802B2 (ja) 2009-08-05
US6500659B1 (en) 2002-12-31
US6136583A (en) 2000-10-24
EP0937139B1 (en) 2004-09-01
JP2000512849A (ja) 2000-10-03
AU3372897A (en) 1998-01-07
DE69730514D1 (de) 2004-10-07
EP0937139A1 (en) 1999-08-25
ES2227701T3 (es) 2005-04-01
US5877001A (en) 1999-03-02
US6429004B1 (en) 2002-08-06
AU723433B2 (en) 2000-08-24

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