CA2254871C - Purification of biologically active peptides from milk - Google Patents
Purification of biologically active peptides from milk Download PDFInfo
- Publication number
- CA2254871C CA2254871C CA002254871A CA2254871A CA2254871C CA 2254871 C CA2254871 C CA 2254871C CA 002254871 A CA002254871 A CA 002254871A CA 2254871 A CA2254871 A CA 2254871A CA 2254871 C CA2254871 C CA 2254871C
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- Prior art keywords
- milk
- protein
- capture device
- component
- permeate
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/832—Milk; colostrum
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/648,235 | 1996-05-13 | ||
| US08/648,235 US6268487B1 (en) | 1996-05-13 | 1996-05-13 | Purification of biologically active peptides from milk |
| PCT/US1997/008044 WO1997042835A1 (en) | 1996-05-13 | 1997-05-13 | Purification of biologically active peptides from milk |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2254871A1 CA2254871A1 (en) | 1997-11-20 |
| CA2254871C true CA2254871C (en) | 2008-03-25 |
Family
ID=24599969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002254871A Expired - Lifetime CA2254871C (en) | 1996-05-13 | 1997-05-13 | Purification of biologically active peptides from milk |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6268487B1 (https=) |
| EP (1) | EP0923308B1 (https=) |
| JP (1) | JP4476362B2 (https=) |
| AT (1) | ATE224145T1 (https=) |
| AU (1) | AU725993B2 (https=) |
| CA (1) | CA2254871C (https=) |
| DE (2) | DE69715641T2 (https=) |
| DK (1) | DK0923308T3 (https=) |
| ES (1) | ES2182074T3 (https=) |
| LU (1) | LU91305I2 (https=) |
| NL (1) | NL300256I2 (https=) |
| NZ (1) | NZ332916A (https=) |
| PT (1) | PT923308E (https=) |
| WO (1) | WO1997042835A1 (https=) |
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| DE122007000007I2 (de) | 1986-04-09 | 2010-12-30 | Genzyme Corp | Genetisch transformierte Tiere, die ein gewünschtes Protein in Milch absondern |
| EP1025244A2 (en) | 1997-10-20 | 2000-08-09 | Genzyme Transgenics Corporation | NOVEL MODIFIED MSP-1 NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS |
| SE9802213D0 (sv) * | 1998-06-18 | 1998-06-18 | Amersham Pharm Biotech Ab | A method for the removal/purification of serum albumins and means for use in the method |
| US20030005468A1 (en) * | 1998-06-19 | 2003-01-02 | Meade Harry M. | Methods and vectors for improving nucleic acid expression |
| DK1115745T3 (da) * | 1998-09-24 | 2006-10-02 | Pharming Intellectual Pty Bv | Oprensning af fibrinogen fra væsker ved udfældning og hydrofob interaktionskromatografi |
| CA2354638C (en) * | 1999-01-06 | 2013-03-19 | Atlantic Biopharmaceuticals, Inc. | Expression of secreted human alpha-fetoprotein in transgenic animals |
| EP1194570A1 (en) | 1999-06-23 | 2002-04-10 | PPL Therapeutics (Scotland) Limited | Fusion proteins incorporating lysozyme |
| NZ522971A (en) * | 2000-05-05 | 2005-02-25 | Gtc Biotherapeutics Inc | Transgenically produced decorin in the mammary gland of a transgenic animal |
| US20020077775A1 (en) * | 2000-05-25 | 2002-06-20 | Schork Nicholas J. | Methods of DNA marker-based genetic analysis using estimated haplotype frequencies and uses thereof |
| US20030195707A1 (en) * | 2000-05-25 | 2003-10-16 | Schork Nicholas J | Methods of dna marker-based genetic analysis using estimated haplotype frequencies and uses thereof |
| US20040226053A1 (en) * | 2000-10-13 | 2004-11-11 | Meade Harry M. | Methods of producing a target molecule in a transgenic animal and purification of the target molecule |
| JP2004536081A (ja) * | 2001-06-13 | 2004-12-02 | トーラス エイチエスエイ エルエルシー | ヒト血清アルブミンの精製 |
| IL160229A0 (en) * | 2001-08-10 | 2004-07-25 | Genset Sa | Polynucleotides, polypeptides encoded thereby and their use |
| US6875459B2 (en) * | 2001-09-10 | 2005-04-05 | Henry B. Kopf | Method and apparatus for separation of milk, colostrum, and whey |
| US20060253913A1 (en) * | 2001-12-21 | 2006-11-09 | Yue-Jin Huang | Production of hSA-linked butyrylcholinesterases in transgenic mammals |
| AU2003247354A1 (en) * | 2002-04-24 | 2003-11-10 | Intermediate ingredient for dairy product manufacturing and method of making the same | |
| EP1367065B1 (en) * | 2002-05-27 | 2008-07-30 | Nestec S.A. | Acid soluble proteins from micellar casein |
| GB0216001D0 (en) * | 2002-07-10 | 2002-08-21 | Nat Blood Authority | Process and composition |
| US20040092719A1 (en) * | 2002-09-17 | 2004-05-13 | Eszter Birck-Wilson | Isolation of immunoglobulin molecules that lack inter-heavy chain disulfide bonds |
| CA2506629A1 (en) * | 2002-11-27 | 2004-06-17 | Gtc Biotherapeutics, Inc. | Modified antibodies stably produced in milk and methods of producing same |
| US20040210953A1 (en) * | 2003-01-09 | 2004-10-21 | Murray James D. | Lysozyme transgenic ungulates |
| US20040231010A1 (en) * | 2003-01-09 | 2004-11-18 | Murray James D. | Lysozyme transgenic ungulates |
| ES2371913T3 (es) | 2003-01-22 | 2012-01-11 | Duke University | Constructos mejorados para expresar polipéptidos lisosomales. |
| AU2003261387A1 (en) * | 2003-02-24 | 2004-09-17 | Gtc Biotherapeutics, Inc. | Methods of tangential flow filtration and an apparatus therefore |
| WO2005085287A1 (en) | 2004-03-03 | 2005-09-15 | En-N-Tech, Inc. | Treatments for contaminant reduction in lactoferrin preparations and lactoferrin-containing compositions |
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| US20050245444A1 (en) * | 2004-04-30 | 2005-11-03 | Yann Echelard | Method of using recombinant human antithrombin for neurocognitive disorders |
| US20060121004A1 (en) * | 2004-12-07 | 2006-06-08 | Yann Echelard | Methods of reducing the incidence of rejection in tissue transplantation through the use of recombinant human antithrombin |
| US20060130159A1 (en) * | 2004-12-09 | 2006-06-15 | Nick Masiello | Method of purifying recombinant MSP 1-42 derived from Plasmodium falciparum |
| US20080019905A9 (en) * | 2005-02-18 | 2008-01-24 | Strome Scott E | Method of using an anti-CD137 antibody as an agent for radioimmunotherapy or radioimmunodetection |
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| KR20140133958A (ko) * | 2005-10-21 | 2014-11-20 | 엘에프비 유에스에이, 인크. | 항체 의존성 세포 독성 활성이 증강된 항체, 그 생산 및 사용 방법 |
| US7531632B2 (en) * | 2006-02-16 | 2009-05-12 | Gtc Biotherapeutics, Inc. | Clarification of transgenic milk using depth filtration |
| FR2901707B1 (fr) | 2006-05-31 | 2017-09-29 | Lab Francais Du Fractionnement | Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis |
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| US10034921B2 (en) | 2013-02-13 | 2018-07-31 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| EP3594230A1 (en) | 2013-02-13 | 2020-01-15 | Laboratoire Français du Fractionnement et des Biotechnologies | Highly galactosylated anti-tnf-alpha antibodies and uses thereof |
| EP3016729B1 (fr) | 2013-07-05 | 2020-03-25 | Laboratoire Francais du Fractionnement et des Biotechnologies Societe Anonyme | Matrice de chromatographie d'affinité |
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| KR20170040132A (ko) * | 2014-06-02 | 2017-04-12 | 라보라토이레 프란카이즈 듀 프락티온네먼트 에트 데스 바이오테크놀로지스 | Fc 단편의 제조 |
| KR20190011838A (ko) | 2014-06-26 | 2019-02-07 | 이엠디 밀리포어 코포레이션 | 개선된 먼지 포집 능력을 갖는 필터 구조 |
| FR3034419B1 (fr) | 2015-04-02 | 2017-12-15 | Lab Francais Du Fractionnement | Procede de purification d'une proteine recombinante therapeutique a partir d'un lait transgenique |
| KR102206959B1 (ko) * | 2015-04-17 | 2021-01-25 | 이엠디 밀리포어 코포레이션 | 접선방향 유동 여과 모드에서 작동되는 나노섬유 한외여과막을 사용하여 샘플에서 목적하는 생물학적 물질을 정제하는 방법 |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
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| WO2022024828A1 (ja) * | 2020-07-29 | 2022-02-03 | 和弘 原 | 成分調整物生産装置及び成分調整物生産方法 |
| CN113101737B (zh) * | 2021-03-04 | 2023-09-15 | 京美生命科技(杭州)有限公司 | 一种亲和切向流过滤系统及其构建方法和外泌体提取方法及应用 |
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| US5256294A (en) | 1990-09-17 | 1993-10-26 | Genentech, Inc. | Tangential flow filtration process and apparatus |
| US5175013A (en) | 1990-12-31 | 1992-12-29 | The Pillsbury Company | Frozen dessert compositions and products |
| US5178894A (en) | 1991-09-26 | 1993-01-12 | Silvia P. Rudel | High non-fat milk content bread products having improved keeping qualities |
| US5256437A (en) * | 1992-06-19 | 1993-10-26 | Pall Corporation | Product and process of making sterile milk through dynamic microfiltration |
| WO1994019935A1 (en) | 1993-03-09 | 1994-09-15 | Genzyme Corporation | Isolation of components of interest from milk |
| EP0744901B1 (en) | 1994-02-16 | 2001-12-05 | Pharming Intellectual Property BV | Isolation of lactoferrin from milk |
| US5597486A (en) * | 1995-05-01 | 1997-01-28 | Millipore Investment Holdings Limited | Membrane filtration with optimized addition of second liquid to maximize flux |
-
1996
- 1996-05-13 US US08/648,235 patent/US6268487B1/en not_active Expired - Lifetime
-
1997
- 1997-05-13 EP EP97923643A patent/EP0923308B1/en not_active Expired - Lifetime
- 1997-05-13 AT AT97923643T patent/ATE224145T1/de active
- 1997-05-13 DE DE69715641T patent/DE69715641T2/de not_active Expired - Lifetime
- 1997-05-13 JP JP54103697A patent/JP4476362B2/ja not_active Expired - Lifetime
- 1997-05-13 WO PCT/US1997/008044 patent/WO1997042835A1/en not_active Ceased
- 1997-05-13 DE DE122007000008C patent/DE122007000008I2/de active Active
- 1997-05-13 DK DK97923643T patent/DK0923308T3/da active
- 1997-05-13 CA CA002254871A patent/CA2254871C/en not_active Expired - Lifetime
- 1997-05-13 PT PT97923643T patent/PT923308E/pt unknown
- 1997-05-13 AU AU29402/97A patent/AU725993B2/en not_active Expired
- 1997-05-13 ES ES97923643T patent/ES2182074T3/es not_active Expired - Lifetime
- 1997-05-13 NZ NZ332916A patent/NZ332916A/xx not_active IP Right Cessation
-
2007
- 2007-01-12 LU LU91305C patent/LU91305I2/fr unknown
- 2007-01-19 NL NL300256C patent/NL300256I2/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6268487B1 (en) | 2001-07-31 |
| AU2940297A (en) | 1997-12-05 |
| ATE224145T1 (de) | 2002-10-15 |
| LU91305I2 (fr) | 2007-03-12 |
| PT923308E (pt) | 2002-11-29 |
| CA2254871A1 (en) | 1997-11-20 |
| NL300256I2 (nl) | 2007-09-03 |
| EP0923308B1 (en) | 2002-09-18 |
| DE122007000008I2 (de) | 2011-01-13 |
| DE122007000008I1 (de) | 2009-05-20 |
| JP2000510701A (ja) | 2000-08-22 |
| EP0923308A4 (https=) | 1999-06-30 |
| DE69715641D1 (de) | 2002-10-24 |
| ES2182074T3 (es) | 2003-03-01 |
| DE69715641T2 (de) | 2003-08-07 |
| NZ332916A (en) | 2000-05-26 |
| NL300256I1 (nl) | 2007-04-02 |
| DK0923308T3 (da) | 2002-10-14 |
| EP0923308A1 (en) | 1999-06-23 |
| AU725993B2 (en) | 2000-10-26 |
| WO1997042835A1 (en) | 1997-11-20 |
| JP4476362B2 (ja) | 2010-06-09 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20170515 |