CA2238954A1 - Discontinuous countercurrent chromatographic process and apparatus - Google Patents

Discontinuous countercurrent chromatographic process and apparatus Download PDF

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Publication number
CA2238954A1
CA2238954A1 CA002238954A CA2238954A CA2238954A1 CA 2238954 A1 CA2238954 A1 CA 2238954A1 CA 002238954 A CA002238954 A CA 002238954A CA 2238954 A CA2238954 A CA 2238954A CA 2238954 A1 CA2238954 A1 CA 2238954A1
Authority
CA
Canada
Prior art keywords
pump
solvent
chromatographic
columns
mobile phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002238954A
Other languages
English (en)
French (fr)
Inventor
Charles M. Grill
Thomas W. Hampton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Merck Patent GmbH
EMD Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH, EMD Chemicals Inc filed Critical Merck Patent GmbH
Publication of CA2238954A1 publication Critical patent/CA2238954A1/en
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/44—Flow patterns using recycling of the fraction to be distributed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B01D15/1857—Reactive simulated moving beds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
CA002238954A 1995-11-30 1996-11-12 Discontinuous countercurrent chromatographic process and apparatus Abandoned CA2238954A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/566,425 US5630943A (en) 1995-11-30 1995-11-30 Discontinuous countercurrent chromatographic process and apparatus
US08/566,425 1995-11-30

Publications (1)

Publication Number Publication Date
CA2238954A1 true CA2238954A1 (en) 1997-06-05

Family

ID=24262836

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002238954A Abandoned CA2238954A1 (en) 1995-11-30 1996-11-12 Discontinuous countercurrent chromatographic process and apparatus

Country Status (6)

Country Link
US (1) US5630943A (enExample)
EP (1) EP0877936B1 (enExample)
JP (1) JP4009671B2 (enExample)
CA (1) CA2238954A1 (enExample)
DE (1) DE69631903T2 (enExample)
WO (1) WO1997020206A1 (enExample)

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Also Published As

Publication number Publication date
JP2000503112A (ja) 2000-03-14
DE69631903D1 (de) 2004-04-22
US5630943A (en) 1997-05-20
WO1997020206A1 (en) 1997-06-05
JP4009671B2 (ja) 2007-11-21
EP0877936B1 (en) 2004-03-17
DE69631903T2 (de) 2004-08-19
EP0877936A1 (en) 1998-11-18

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Legal Events

Date Code Title Description
FZDE Discontinued