CA2225552A1 - Quinolones and their therapeutic use - Google Patents
Quinolones and their therapeutic use Download PDFInfo
- Publication number
- CA2225552A1 CA2225552A1 CA002225552A CA2225552A CA2225552A1 CA 2225552 A1 CA2225552 A1 CA 2225552A1 CA 002225552 A CA002225552 A CA 002225552A CA 2225552 A CA2225552 A CA 2225552A CA 2225552 A1 CA2225552 A1 CA 2225552A1
- Authority
- CA
- Canada
- Prior art keywords
- ethyl
- dihydro
- oxo
- quinolinecarboxamide
- pyridyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
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- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Diabetes (AREA)
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- Epidemiology (AREA)
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- Oncology (AREA)
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- Endocrinology (AREA)
- Virology (AREA)
- Psychiatry (AREA)
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- Dermatology (AREA)
- Cardiology (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9515811.9A GB9515811D0 (en) | 1995-08-02 | 1995-08-02 | Novel compounds |
| GB9515811.9 | 1995-08-02 | ||
| GBGB9526377.8A GB9526377D0 (en) | 1995-12-22 | 1995-12-22 | Novel compounds |
| GB9526377.8 | 1995-12-22 | ||
| GBGB9605868.0A GB9605868D0 (en) | 1996-03-20 | 1996-03-20 | Novel compounds |
| GB9605868.0 | 1996-03-20 | ||
| GBGB9611898.9A GB9611898D0 (en) | 1996-06-07 | 1996-06-07 | Quinolones and their therapeutic use |
| GB9611898.9 | 1996-06-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2225552A1 true CA2225552A1 (en) | 1997-02-13 |
Family
ID=27451319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002225552A Abandoned CA2225552A1 (en) | 1995-08-02 | 1996-08-02 | Quinolones and their therapeutic use |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5891878A (enExample) |
| EP (1) | EP0841929B1 (enExample) |
| JP (1) | JPH11513021A (enExample) |
| AT (1) | ATE239477T1 (enExample) |
| AU (1) | AU696390B2 (enExample) |
| CA (1) | CA2225552A1 (enExample) |
| DE (1) | DE69628019T2 (enExample) |
| DK (1) | DK0841929T3 (enExample) |
| ES (1) | ES2193252T3 (enExample) |
| MX (1) | MX9800922A (enExample) |
| PT (1) | PT841929E (enExample) |
| WO (1) | WO1997004779A1 (enExample) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6077850A (en) * | 1997-04-21 | 2000-06-20 | G.D. Searle & Co. | Substituted benzopyran analogs for the treatment of inflammation |
| IT1296985B1 (it) | 1997-12-19 | 1999-08-03 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
| ATE303993T1 (de) * | 1997-12-22 | 2005-09-15 | Pharmacia & Upjohn Co Llc | 4-hydroxychinolin-3-carboxamide und hydrazide als antivirale wirkstoffe |
| IT1302677B1 (it) | 1998-10-15 | 2000-09-29 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
| US6248736B1 (en) * | 1999-01-08 | 2001-06-19 | Pharmacia & Upjohn Company | 4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents |
| US6248739B1 (en) * | 1999-01-08 | 2001-06-19 | Pharmacia & Upjohn Company | Quinolinecarboxamides as antiviral agents |
| HRP20020158B1 (en) | 1999-08-21 | 2007-08-31 | Altana Pharma Ag | Action of synergistic combination |
| US6436971B2 (en) * | 2000-02-09 | 2002-08-20 | Smithkline Beecham Corporation | Use of PDE 4-specific inhibitors to reduce the severity of a bacterial infection after a respiratory viral infection |
| SI1265873T1 (en) | 2000-03-21 | 2004-02-29 | Pharmacia & Upjohn Company | 4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents |
| AU2001243240A1 (en) | 2000-03-21 | 2001-10-15 | Pharmacia And Upjohn Company Llc | 4-oxo-1,4-dihydro(1,8)naphthyridine-3-carboxamides as antiviral agents |
| CN1398258A (zh) | 2000-03-21 | 2003-02-19 | 法玛西雅厄普约翰美国公司 | 用作抗病毒剂的4－羟基噌啉－3－甲酰胺化合物 |
| HK1054037A1 (zh) | 2000-03-21 | 2003-11-14 | 法玛西雅厄普约翰美国公司 | 作为抗病毒剂的4-羟基-1，8-二氮杂萘-3-羧酰胺 |
| PE20011349A1 (es) * | 2000-06-16 | 2002-01-19 | Upjohn Co | 1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales |
| US6730682B2 (en) * | 2000-07-12 | 2004-05-04 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| US6559145B2 (en) | 2000-07-12 | 2003-05-06 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| US6562822B2 (en) | 2000-07-12 | 2003-05-13 | Pharmacia & Upjohn Company | Heterocyle carboxamides as antiviral agents |
| PE20020856A1 (es) | 2001-02-13 | 2002-11-11 | Aventis Pharma Gmbh | 1,2,3,4-tetrahidronaftil aminas aciladas |
| TWI243164B (en) | 2001-02-13 | 2005-11-11 | Aventis Pharma Gmbh | Acylated indanyl amines and their use as pharmaceuticals |
| CA2433467A1 (en) | 2001-03-01 | 2002-09-12 | Joseph W. Strohbach | Substituted quinolinecarboxamides as antiviral agents |
| BR0212829A (pt) * | 2001-09-26 | 2004-08-03 | Bayer Pharmaceuticals Corp | Derivados de 1,8-naftiridina e seu uso para tratar diabetes e distúrbios relacionados |
| US7186707B2 (en) * | 2002-04-01 | 2007-03-06 | University Of Florida | Prodrugs for use as ophthalmic agents |
| WO2003084978A1 (en) * | 2002-04-01 | 2003-10-16 | University Of Florida | Steroidal quinols as prodrugs of antioxidants |
| US7300926B2 (en) * | 2002-04-01 | 2007-11-27 | University Of Florida Research Foundation, Inc. | Steroidal quinols and their use for estrogen replacement therapy |
| US20070213310A1 (en) * | 2002-04-01 | 2007-09-13 | Laszlo Prokai | Prodrugs for Use as Ophthalmic Agents |
| EP1569648A4 (en) * | 2002-12-09 | 2006-10-04 | Univ Florida | PRODRUGS FOR OPHTHALMIKA |
| EP1624893A2 (en) | 2003-04-01 | 2006-02-15 | Applied Research Systems ARS Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| KR20060041254A (ko) | 2003-07-24 | 2006-05-11 | 아스텔라스세이야쿠 가부시키가이샤 | 퀴놀론 유도체 또는 그의 염 |
| DE102004004971B3 (de) * | 2004-01-31 | 2005-09-15 | Aventis Pharma Deutschland Gmbh | Cycloalkyl substituierte 7-Amino-4-chinolon-3-carbonsäure-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arnzeimittel |
| US7470706B2 (en) * | 2004-01-31 | 2008-12-30 | Sanofi-Aventis Deutschland Gmbh | Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments |
| JP4775259B2 (ja) | 2004-03-31 | 2011-09-21 | 味の素株式会社 | アニリン誘導体 |
| RU2525115C2 (ru) * | 2004-06-24 | 2014-08-10 | Вертекс Фармасьютикалз Инкорпорейтед | Способ модуляции транспортеров атф-связывающей кассеты |
| US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| PT1773816E (pt) * | 2004-06-24 | 2015-04-29 | Vertex Pharma | Moduladores de transportadores de cassete de ligação de atp |
| EP3216787B1 (en) * | 2004-06-24 | 2020-02-19 | Vertex Pharmaceuticals Incorporated | Intermediates for the preparation of modulators of atp-binding cassette transporters |
| DE102004035203A1 (de) | 2004-07-21 | 2006-02-16 | Bayer Healthcare Ag | Substituierte Chinolone |
| DE102005030524A1 (de) | 2005-06-30 | 2007-01-18 | Aicuris Gmbh & Co. Kg | Substituierte Chinolone II |
| EP1979367A2 (en) * | 2005-12-24 | 2008-10-15 | Vertex Pharmaceuticals Incorporated | Quinolin-4-one derivatives as modulators of abc transporters |
| AU2006331565A1 (en) * | 2005-12-27 | 2007-07-05 | Vertex Pharmaceuticals Incorporated | Compounds useful in CFTR assays and methods therewith |
| RS55940B1 (sr) | 2005-12-28 | 2017-09-29 | Vertex Pharma | Čvrsti oblici n-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksohinolin-3-karboksamida |
| DE102006005861A1 (de) | 2006-02-09 | 2007-08-23 | Aicuris Gmbh & Co. Kg | Substituierte Chinolone III |
| JP5424480B2 (ja) * | 2006-03-13 | 2014-02-26 | 杏林製薬株式会社 | Ｇｓｋ−３インヒビターとしてのアミノキノロン |
| US12458635B2 (en) | 2008-08-13 | 2025-11-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| PL2349263T3 (pl) | 2008-10-23 | 2014-11-28 | Vertex Pharma | Modulatory mukowiscydozowego regulatora przewodnictwa przezbłonowego |
| EP2821400B1 (en) | 2009-03-20 | 2017-09-27 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| MX2014010253A (es) | 2012-02-27 | 2014-11-12 | Vertex Pharma | Composicion farmaceutica y administraciones de la misma. |
| GB201409044D0 (en) | 2014-05-21 | 2014-07-02 | Ucl Business Plc | New compounds |
| RU2749213C2 (ru) | 2014-10-07 | 2021-06-07 | Вертекс Фармасьютикалз Инкорпорейтед | Сокристаллы модуляторов регулятора трансмембранной проводимости при кистозном фиброзе |
| CN107998131B (zh) * | 2017-12-27 | 2019-09-24 | 湖北工业大学 | 芳香酯类化合物用于制备抗adv-7病毒药物 |
| CN111646941A (zh) * | 2020-07-17 | 2020-09-11 | 天津科技大学 | 一种磺酰胺类衍生物及其制备方法和应用 |
Family Cites Families (5)
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|---|---|---|---|---|
| US3524558A (en) * | 1967-03-30 | 1970-08-18 | American Mach & Foundry | Cargo loading means and method |
| US3524858A (en) * | 1967-05-18 | 1970-08-18 | Warner Lambert Pharmaceutical | 1,4 - dihydro-1-substituted alkyl-6,7-methylenedioxy - 4 - oxoquinoline-3-carboxylic acid |
| FR2564832B1 (fr) * | 1984-05-23 | 1987-05-15 | Panmedica Sa | Nouveaux n-acyl derives d'amino-acides et leurs esters, leur procede de preparation et medicaments les contenant |
| US4786644A (en) * | 1987-11-27 | 1988-11-22 | Hoechst-Roussel Pharmaceuticals Inc. | 1-aryl-3-quinolinecarboxamide |
| JPH02124871A (ja) * | 1988-07-27 | 1990-05-14 | Dainippon Pharmaceut Co Ltd | １位が置換された複素環式カルボン酸アミド誘導体 |
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1996
- 1996-08-02 MX MX9800922A patent/MX9800922A/es not_active IP Right Cessation
- 1996-08-02 PT PT96925905T patent/PT841929E/pt unknown
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- 1996-08-02 EP EP96925905A patent/EP0841929B1/en not_active Expired - Lifetime
- 1996-08-02 CA CA002225552A patent/CA2225552A1/en not_active Abandoned
- 1996-08-02 JP JP9507373A patent/JPH11513021A/ja not_active Ceased
- 1996-08-02 DK DK96925905T patent/DK0841929T3/da active
- 1996-08-02 AU AU66263/96A patent/AU696390B2/en not_active Ceased
- 1996-08-02 ES ES96925905T patent/ES2193252T3/es not_active Expired - Lifetime
- 1996-08-02 US US08/691,338 patent/US5891878A/en not_active Expired - Fee Related
- 1996-08-02 AT AT96925905T patent/ATE239477T1/de not_active IP Right Cessation
- 1996-08-02 WO PCT/GB1996/001862 patent/WO1997004779A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU696390B2 (en) | 1998-09-10 |
| ATE239477T1 (de) | 2003-05-15 |
| PT841929E (pt) | 2003-09-30 |
| DE69628019T2 (de) | 2004-01-22 |
| ES2193252T3 (es) | 2003-11-01 |
| US5891878A (en) | 1999-04-06 |
| AU6626396A (en) | 1997-02-26 |
| DK0841929T3 (da) | 2003-09-01 |
| JPH11513021A (ja) | 1999-11-09 |
| WO1997004779A1 (en) | 1997-02-13 |
| EP0841929A1 (en) | 1998-05-20 |
| DE69628019D1 (de) | 2003-06-12 |
| EP0841929B1 (en) | 2003-05-07 |
| MX9800922A (es) | 1998-05-31 |
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