CA2223235A1 - Detection of htlv antibodies utilizing recombinant proteins - Google Patents

Detection of htlv antibodies utilizing recombinant proteins Download PDF

Info

Publication number
CA2223235A1
CA2223235A1 CA 2223235 CA2223235A CA2223235A1 CA 2223235 A1 CA2223235 A1 CA 2223235A1 CA 2223235 CA2223235 CA 2223235 CA 2223235 A CA2223235 A CA 2223235A CA 2223235 A1 CA2223235 A1 CA 2223235A1
Authority
CA
Canada
Prior art keywords
htlv
antigen
sequence
recombinant
capture reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2223235
Other languages
English (en)
French (fr)
Inventor
Sean F. Nowlan
R. Keith Hickman
Jessie W. Shih
Michael B. Cerney
Sushil G. Devare
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2223235A1 publication Critical patent/CA2223235A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • G01N33/56988HIV or HTLV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/14011Deltaretrovirus, e.g. bovine leukeamia virus
    • C12N2740/14022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA 2223235 1995-06-05 1996-06-04 Detection of htlv antibodies utilizing recombinant proteins Abandoned CA2223235A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46209795A 1995-06-05 1995-06-05
US08/462,097 1995-06-05

Publications (1)

Publication Number Publication Date
CA2223235A1 true CA2223235A1 (en) 1996-12-12

Family

ID=23835158

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2223235 Abandoned CA2223235A1 (en) 1995-06-05 1996-06-04 Detection of htlv antibodies utilizing recombinant proteins

Country Status (4)

Country Link
EP (1) EP0848820A1 (ja)
JP (1) JP2001510553A (ja)
CA (1) CA2223235A1 (ja)
WO (1) WO1996039630A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200409815A (en) 2002-12-12 2004-06-16 Dev Center Biotechnology Human T-lymphotrophic virus (HTLV) fusion protein, nucleic acid and vector encoding the protein, and kit for testing human T-lymphotrophic virus using the protein
DE602004005624T2 (de) * 2003-04-25 2007-12-27 Development Center For Biotechnology Antigene Fragmente vom gp21 Hüllprotein des humanen T-lymphotropen Virus HTLV
EP2913338A1 (en) 2014-02-28 2015-09-02 Roche Diagniostics GmbH Soluable and immunoreactive variants of HTLV capsid antigen p24

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ213823A (en) * 1984-10-26 1988-05-30 Us Health Producing human t-cell leukemia retrovirus envelope protein fragments in bacteria
WO1991007510A1 (en) * 1989-11-17 1991-05-30 Amgen Inc. A method of detecting htlv-i antibodies in human body fluids
WO1993001316A1 (en) * 1991-07-10 1993-01-21 Abbott Laboratories Differentiation of htlv-i and htlv-ii using synthetic peptides
US6406841B1 (en) * 1993-07-01 2002-06-18 Abbott Laboratories Methods for the detection of HTLV-II antibodies employing novel HTLV-II NRA envelope peptides

Also Published As

Publication number Publication date
WO1996039630A1 (en) 1996-12-12
EP0848820A1 (en) 1998-06-24
JP2001510553A (ja) 2001-07-31

Similar Documents

Publication Publication Date Title
CA2032381C (en) Viral agent
US6406841B1 (en) Methods for the detection of HTLV-II antibodies employing novel HTLV-II NRA envelope peptides
NZ197734A (en) Synthetic peptides which substantially duplicate the sequences of naturally-occurring specific antigenic determinants;method of preparing antigens,antibodies thereto,and vaccines
US6383765B1 (en) Polypeptides of feline T-cell lymphotropic lentivirus
WO1995001457A9 (en) Htlv-iinra compositions and assays for detecting htlv infection
EP0471752A1 (en) Polypeptides of feline t-cell lymphotropic lentivirus
JP3506252B2 (ja) Htlv−i/htlv−iiの分析及び方法
CA2271449C (en) Diagnosis of feline immunodeficiency virus infection using env/gag polypeptide markers
Hadlock et al. Cloning and analysis of a recombinant antigen containing an epitope specific for human T-cell lymphotropic virus type II
CA2223235A1 (en) Detection of htlv antibodies utilizing recombinant proteins
DE69106141T2 (de) Non-a non-b sequenzen.
JP3421336B2 (ja) 合成ペプチドを用いてのhtlv−▲i▼とhtlv−▲ii▼との区別
JP3470899B2 (ja) 診断に使用するためのhtlv−▲i▼およびhtlv−▲ii▼gp21由来ペプチド
WO1991007664A1 (en) Diagnostic proteins to test for more than one antibody
US6039957A (en) Oligomeric HIV-1 envelope glycoproteins
EP0951646B1 (en) THE IMMUNOENZIMATIC ASSAY FOR THE DIAGNOSIS OF EQUINE INFECTIOUS ANEMIA VIRUS DISEASE BY USING RECOMBINANT PROTEIN (rGP90) DERIVED FROM EQUINE INFECTIOUS ANEMIA VIRUS
AU680821B2 (en) Measles virus-specific antibody detection using recombinant measles proteins
JPH04505621A (ja) Tリンパ球向性レトロウイルス単クローン抗体
US20030207261A1 (en) Method and composition for the diagnosis of equine infectious anemia virus disease by using the recombinant capsid protein virus (P26)
US5445932A (en) Method for detection of a new marker associated with hepatitis delta virus infection
JP2000078973A (ja) Htlv−i組換え抗原
JP2930966B2 (ja) ポリペプチドを抗原とするモノクローナル抗体
US6416761B1 (en) Rio Mamoré hantavirus nucleocapsid protein and diagnostic methods employing said protein
EP0628572A2 (en) DNA originating in non-A non-B hepatitis virus gene and constituting polypeptide
WO2001012816A2 (en) Porcine endovirus gag and env and diagnostic uses thereof

Legal Events

Date Code Title Description
FZDE Dead