CA2223235A1 - Detection d'anticorps du htlv a l'aide de proteines de recombinaison - Google Patents

Detection d'anticorps du htlv a l'aide de proteines de recombinaison Download PDF

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Publication number
CA2223235A1
CA2223235A1 CA 2223235 CA2223235A CA2223235A1 CA 2223235 A1 CA2223235 A1 CA 2223235A1 CA 2223235 CA2223235 CA 2223235 CA 2223235 A CA2223235 A CA 2223235A CA 2223235 A1 CA2223235 A1 CA 2223235A1
Authority
CA
Canada
Prior art keywords
htlv
antigen
sequence
recombinant
capture reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2223235
Other languages
English (en)
Inventor
Sean F. Nowlan
R. Keith Hickman
Jessie W. Shih
Michael B. Cerney
Sushil G. Devare
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2223235A1 publication Critical patent/CA2223235A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/14011—Deltaretrovirus, e.g. bovine leukeamia virus
    • C12N2740/14022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention porte sur des techniques recourant à des antigènes de recombinaison de l'HTLV-I et de l'HTLV-II pour détecter les anticorps du HTVL dans un échantillon test. Les antigènes utilisés comprennent les HTLV-Igp46, HTLV-Igp21, HTLV-Ip24, HTLV-IIgp21 et HTLV-IIgp24 ou l'une de leurs combinaisons. L'invention porte également sur les trousses qui comprennent les antigènes de l'HTLV-I et de l'HTLV-II, et les plasmides à partir desquels ces antigènes de recombinaison ont été produits.
CA 2223235 1995-06-05 1996-06-04 Detection d'anticorps du htlv a l'aide de proteines de recombinaison Abandoned CA2223235A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46209795A 1995-06-05 1995-06-05
US08/462,097 1995-06-05

Publications (1)

Publication Number Publication Date
CA2223235A1 true CA2223235A1 (fr) 1996-12-12

Family

ID=23835158

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2223235 Abandoned CA2223235A1 (fr) 1995-06-05 1996-06-04 Detection d'anticorps du htlv a l'aide de proteines de recombinaison

Country Status (4)

Country Link
EP (1) EP0848820A1 (fr)
JP (1) JP2001510553A (fr)
CA (1) CA2223235A1 (fr)
WO (1) WO1996039630A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200409815A (en) 2002-12-12 2004-06-16 Dev Center Biotechnology Human T-lymphotrophic virus (HTLV) fusion protein, nucleic acid and vector encoding the protein, and kit for testing human T-lymphotrophic virus using the protein
EP1477495B1 (fr) * 2003-04-25 2007-04-04 Development Center For Biotechnology Fragments antigéniqes de la protéine gp21 du virus lymphotropique humain HTLV
EP2913338A1 (fr) * 2014-02-28 2015-09-02 Roche Diagniostics GmbH Variants et immunoréactif soluble de HTLV antigène capsidique p24

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ213823A (en) * 1984-10-26 1988-05-30 Us Health Producing human t-cell leukemia retrovirus envelope protein fragments in bacteria
WO1991007510A1 (fr) * 1989-11-17 1991-05-30 Amgen Inc. Methode de detection d'anticorps htlv-i dans les fluides corporels humains
JP3421336B2 (ja) * 1991-07-10 2003-06-30 アボツト・ラボラトリーズ 合成ペプチドを用いてのｈｔｌｖ−▲ｉ▼とｈｔｌｖ−▲ｉｉ▼との区別
US6406841B1 (en) * 1993-07-01 2002-06-18 Abbott Laboratories Methods for the detection of HTLV-II antibodies employing novel HTLV-II NRA envelope peptides

Also Published As

Publication number Publication date
WO1996039630A1 (fr) 1996-12-12
JP2001510553A (ja) 2001-07-31
EP0848820A1 (fr) 1998-06-24

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