CA2221179A1 - Polymeric peptide probes and uses thereof - Google Patents

Polymeric peptide probes and uses thereof Download PDF

Info

Publication number
CA2221179A1
CA2221179A1 CA 2221179 CA2221179A CA2221179A1 CA 2221179 A1 CA2221179 A1 CA 2221179A1 CA 2221179 CA2221179 CA 2221179 CA 2221179 A CA2221179 A CA 2221179A CA 2221179 A1 CA2221179 A1 CA 2221179A1
Authority
CA
Canada
Prior art keywords
assay
test sample
signal
rrna
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2221179
Other languages
English (en)
French (fr)
Inventor
Lynn Valdivia
Hong Yu
David A. Dunn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2221179A1 publication Critical patent/CA2221179A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA 2221179 1995-05-18 1996-05-16 Polymeric peptide probes and uses thereof Abandoned CA2221179A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44414395A 1995-05-18 1995-05-18
US08/444,143 1995-05-18

Publications (1)

Publication Number Publication Date
CA2221179A1 true CA2221179A1 (en) 1996-11-21

Family

ID=23763680

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2221179 Abandoned CA2221179A1 (en) 1995-05-18 1996-05-16 Polymeric peptide probes and uses thereof

Country Status (4)

Country Link
EP (1) EP0871770A1 (ja)
JP (1) JP2001502881A (ja)
CA (1) CA2221179A1 (ja)
WO (1) WO1996036734A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6169169B1 (en) 1994-05-19 2001-01-02 Dako A/S PNA probes for detection of Neisseria gonorrhoeae and Chlamydia trachomatis
US5888733A (en) * 1995-11-16 1999-03-30 Dako A/S In situ hybridization to detect specific nucleic acid sequences in eucaryotic samples
ATE243761T1 (de) 1996-10-04 2003-07-15 Dako As Sonden zur detektion von mycobakterien
CA2218440A1 (en) * 1996-12-21 1998-06-21 Boehringer Mannheim Gmbh Method of analysis using signal amplification
EP1009862A1 (en) * 1997-08-26 2000-06-21 Microscreen B.V. Rapid detection and identification of micro-organisms
US6300318B1 (en) * 1997-09-16 2001-10-09 Peter E. Nielsen Antibacterial and antibiotic methods using peptide nucleic acids and pharmaceutical compositions therefor
WO2000065092A2 (en) * 1999-04-22 2000-11-02 Science And Technology Corporation Blocking non-specific binding of granulocytes in microorganism detection
WO2000065093A2 (en) * 1999-04-22 2000-11-02 Science And Technology Corporation In situ hybridization methods for reducing the occurrence of false positives and for targeting multiple microorganisms
CA2421043C (en) * 2000-08-30 2012-07-31 Avi Biopharma, Inc. Method for analysis of oligonucleotide analogs
WO2011134474A1 (en) * 2010-04-30 2011-11-03 Exiqon A/S In situ hybridization method and buffer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0462221A1 (en) * 1989-03-07 1991-12-27 Syngene, Inc. In-situ hybridization in suspension for detection or separation of cells
US5539082A (en) * 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
WO1992022670A1 (en) * 1991-06-12 1992-12-23 Genpharm International, Inc. Early detection of transgenic embryos
DE4216949C2 (de) * 1992-05-22 1997-07-24 Christoph Prof Dr Dr Cremer Nichtenzymatisches Verfahren zur In-situ-Hybridisierung bei spezifischen Proben
IL106273A0 (en) * 1992-07-17 1993-11-15 Res Dev Foundation Rapid detection of biopolymers in stained specimens
AU4681393A (en) * 1992-07-17 1994-02-14 Aprogenex, Inc. Background-reducing compounds for probe-mediated in-situ fluorimetric assays
DK0720615T3 (da) * 1993-09-21 2000-10-30 Amersham Pharm Biotech Uk Ltd Forlængelse, amplifikation og sekvensbestemmelse under anvendelse af et kimærisk oligonucleotid
US6169169B1 (en) * 1994-05-19 2001-01-02 Dako A/S PNA probes for detection of Neisseria gonorrhoeae and Chlamydia trachomatis

Also Published As

Publication number Publication date
JP2001502881A (ja) 2001-03-06
EP0871770A1 (en) 1998-10-21
WO1996036734A1 (en) 1996-11-21

Similar Documents

Publication Publication Date Title
US20230143970A1 (en) Apparatus and system for nucleic acid detection
US9315854B2 (en) Ultra sensitive method for in situ detection of nucleic acids
JP2819830B2 (ja) インサイチューハイブリダイゼーション法
US7087379B2 (en) Method of detecting single gene copies in-situ
CN103597095B (zh) 用于检测hpv核酸的材料和方法
US7718362B2 (en) DNA chip based genetic typing
AU2004257200A1 (en) Hairpin-labeled probes and methods of use
WO1990010715A1 (en) In-situ hybridization in suspension for detection or separation of cells
US10400275B2 (en) Methods and kits for room temperature in situ detection of a target nucleic acid in a biological sample
JP2011097958A (ja) 特定のStaphylococcus種の分析のためのペプチド核酸プローブ
JP2007506404A (ja) 核酸分子を検出するための迅速な方法
EP3524692A1 (en) Compositions and methods for detection of candida species
CA2221179A1 (en) Polymeric peptide probes and uses thereof
WO1994002645A1 (en) Rapid detection of biopolymers in stained specimens
US9290814B2 (en) Materials and methods for diagnosis of bladder cancer and monitoring recurrence thereof
US20160046984A1 (en) Robust Detection of Nucleic Acids in Situ
EP0862650B1 (en) In situ hybridization to detect specific nucleic acid sequences in eucaryotic samples
US6620586B2 (en) Methods and compositions for analyzing nucleic acids
JP5501220B2 (ja) 特定のStaphylococcus種の分析のためのペプチド核酸プローブ
KR101915211B1 (ko) 멜팅 피크 분석을 이용한 하부요로 생식기 감염균 검출 방법
EP0623177B1 (en) Reversibly bound in dessicated form to a solid support nucleid acid hydridisation probe, method using the same and kit therefor
RU2178173C1 (ru) Способ и набор для определения инфекционных и онкогенных вирусов, интегрированных в хромосомы инфицированных клеток
Thompson Nucleic acid in-situ hybridization detection of infectious agents

Legal Events

Date Code Title Description
FZDE Dead