CA2217264A1 - Calcium supplements and calcium containing beverages comprising vitamin d - Google Patents
Calcium supplements and calcium containing beverages comprising vitamin d Download PDFInfo
- Publication number
- CA2217264A1 CA2217264A1 CA002217264A CA2217264A CA2217264A1 CA 2217264 A1 CA2217264 A1 CA 2217264A1 CA 002217264 A CA002217264 A CA 002217264A CA 2217264 A CA2217264 A CA 2217264A CA 2217264 A1 CA2217264 A1 CA 2217264A1
- Authority
- CA
- Canada
- Prior art keywords
- calcium
- vitamin
- beverage
- concentrate
- gum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims abstract description 209
- 239000011575 calcium Substances 0.000 title claims abstract description 207
- 229910052791 calcium Inorganic materials 0.000 title claims abstract description 204
- 235000013361 beverage Nutrition 0.000 title claims abstract description 169
- 229940046008 vitamin d Drugs 0.000 title claims abstract description 54
- 229940069978 calcium supplement Drugs 0.000 title claims abstract description 15
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims abstract description 228
- 235000001465 calcium Nutrition 0.000 claims abstract description 189
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 83
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 76
- 239000007788 liquid Substances 0.000 claims abstract description 60
- 229930003316 Vitamin D Natural products 0.000 claims abstract description 53
- 235000019166 vitamin D Nutrition 0.000 claims abstract description 53
- 239000011710 vitamin D Substances 0.000 claims abstract description 53
- 150000003710 vitamin D derivatives Chemical class 0.000 claims abstract description 52
- 229920000084 Gum arabic Polymers 0.000 claims abstract description 44
- 235000010489 acacia gum Nutrition 0.000 claims abstract description 43
- 239000000205 acacia gum Substances 0.000 claims abstract description 42
- 235000008504 concentrate Nutrition 0.000 claims abstract description 34
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 24
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 24
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 24
- 239000011718 vitamin C Substances 0.000 claims abstract description 24
- 239000007787 solid Substances 0.000 claims abstract description 12
- 241000416162 Astragalus gummifer Species 0.000 claims abstract description 11
- 229920001615 Tragacanth Polymers 0.000 claims abstract description 11
- 239000001736 Calcium glycerylphosphate Substances 0.000 claims abstract description 10
- 229940095618 calcium glycerophosphate Drugs 0.000 claims abstract description 10
- UHHRFSOMMCWGSO-UHFFFAOYSA-L calcium glycerophosphate Chemical compound [Ca+2].OCC(CO)OP([O-])([O-])=O UHHRFSOMMCWGSO-UHFFFAOYSA-L 0.000 claims abstract description 10
- 235000019299 calcium glycerylphosphate Nutrition 0.000 claims abstract description 10
- 239000012141 concentrate Substances 0.000 claims abstract description 10
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 7
- 239000008158 vegetable oil Substances 0.000 claims abstract description 7
- 239000000230 xanthan gum Substances 0.000 claims abstract description 5
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 5
- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 5
- 229940082509 xanthan gum Drugs 0.000 claims abstract description 5
- 235000005282 vitamin D3 Nutrition 0.000 claims description 184
- 239000011647 vitamin D3 Substances 0.000 claims description 184
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims description 179
- 229940021056 vitamin d3 Drugs 0.000 claims description 175
- 244000215068 Acacia senegal Species 0.000 claims description 43
- 239000000796 flavoring agent Substances 0.000 claims description 30
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 28
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 18
- 235000005687 corn oil Nutrition 0.000 claims description 17
- 239000002285 corn oil Substances 0.000 claims description 17
- 229940092124 calcium citrate malate Drugs 0.000 claims description 15
- 235000014655 lactic acid Nutrition 0.000 claims description 15
- MPCMQXRREZMSPJ-UHFFFAOYSA-L calcium;2-hydroxybutanedioate;2-hydroxypropane-1,2,3-tricarboxylic acid;pentahydrate Chemical group O.O.O.O.O.[Ca+2].[O-]C(=O)C(O)CC([O-])=O.OC(=O)CC(O)(C(O)=O)CC(O)=O MPCMQXRREZMSPJ-UHFFFAOYSA-L 0.000 claims description 14
- 239000004310 lactic acid Substances 0.000 claims description 13
- 239000007864 aqueous solution Substances 0.000 claims description 9
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 9
- 235000003599 food sweetener Nutrition 0.000 claims description 9
- 239000003765 sweetening agent Substances 0.000 claims description 9
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 5
- 238000010790 dilution Methods 0.000 claims description 5
- 239000012895 dilution Substances 0.000 claims description 5
- 229920000642 polymer Polymers 0.000 claims description 5
- 235000013355 food flavoring agent Nutrition 0.000 claims description 4
- 239000008103 glucose Substances 0.000 claims description 4
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims description 3
- 239000004300 potassium benzoate Substances 0.000 claims description 2
- 235000010235 potassium benzoate Nutrition 0.000 claims description 2
- 229940103091 potassium benzoate Drugs 0.000 claims description 2
- 239000008173 hydrogenated soybean oil Substances 0.000 claims 1
- 239000000047 product Substances 0.000 abstract description 70
- 239000000843 powder Substances 0.000 abstract description 22
- 235000016709 nutrition Nutrition 0.000 abstract description 17
- 239000000654 additive Substances 0.000 abstract description 12
- 230000000996 additive effect Effects 0.000 abstract description 10
- 235000011389 fruit/vegetable juice Nutrition 0.000 abstract description 5
- 239000013589 supplement Substances 0.000 abstract description 2
- 241000978776 Senegalia senegal Species 0.000 abstract 1
- 229960005069 calcium Drugs 0.000 description 184
- 239000000523 sample Substances 0.000 description 72
- 239000000243 solution Substances 0.000 description 48
- 239000000839 emulsion Substances 0.000 description 45
- 239000002253 acid Substances 0.000 description 44
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 43
- 241000282320 Panthera leo Species 0.000 description 37
- 238000000034 method Methods 0.000 description 29
- 239000000203 mixture Substances 0.000 description 29
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 26
- 235000019634 flavors Nutrition 0.000 description 26
- 238000011084 recovery Methods 0.000 description 26
- 238000004128 high performance liquid chromatography Methods 0.000 description 25
- 235000013305 food Nutrition 0.000 description 24
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 21
- 239000003921 oil Substances 0.000 description 20
- 235000019198 oils Nutrition 0.000 description 20
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 18
- 229910052782 aluminium Inorganic materials 0.000 description 18
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 18
- 239000001842 Brominated vegetable oil Substances 0.000 description 17
- 235000019323 brominated vegetable oil Nutrition 0.000 description 17
- 238000012546 transfer Methods 0.000 description 17
- 159000000007 calcium salts Chemical class 0.000 description 16
- 235000005911 diet Nutrition 0.000 description 16
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 15
- NHTMVDHEPJAVLT-UHFFFAOYSA-N Isooctane Chemical compound CC(C)CC(C)(C)C NHTMVDHEPJAVLT-UHFFFAOYSA-N 0.000 description 15
- 235000015165 citric acid Nutrition 0.000 description 15
- JVSWJIKNEAIKJW-UHFFFAOYSA-N dimethyl-hexane Natural products CCCCCC(C)C JVSWJIKNEAIKJW-UHFFFAOYSA-N 0.000 description 15
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 15
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 15
- 229940068968 polysorbate 80 Drugs 0.000 description 15
- 229920000053 polysorbate 80 Polymers 0.000 description 15
- 239000012498 ultrapure water Substances 0.000 description 15
- 239000004615 ingredient Substances 0.000 description 14
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 13
- 229960005070 ascorbic acid Drugs 0.000 description 13
- 229910002092 carbon dioxide Inorganic materials 0.000 description 13
- 229960004106 citric acid Drugs 0.000 description 13
- 239000004033 plastic Substances 0.000 description 13
- 229920003023 plastic Polymers 0.000 description 13
- 238000003756 stirring Methods 0.000 description 13
- OFBQJSOFQDEBGM-UHFFFAOYSA-N Pentane Chemical compound CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 12
- 238000004458 analytical method Methods 0.000 description 12
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- 235000010323 ascorbic acid Nutrition 0.000 description 11
- 239000011668 ascorbic acid Substances 0.000 description 11
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 description 10
- 239000001569 carbon dioxide Substances 0.000 description 10
- 239000010941 cobalt Substances 0.000 description 10
- 229910017052 cobalt Inorganic materials 0.000 description 10
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 10
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- 239000002002 slurry Substances 0.000 description 10
- 238000003860 storage Methods 0.000 description 10
- 235000015107 ale Nutrition 0.000 description 9
- 210000000988 bone and bone Anatomy 0.000 description 9
- 239000001354 calcium citrate Substances 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- 239000011159 matrix material Substances 0.000 description 9
- 235000013337 tricalcium citrate Nutrition 0.000 description 9
- 229940088594 vitamin Drugs 0.000 description 9
- 229930003231 vitamin Natural products 0.000 description 9
- 235000013343 vitamin Nutrition 0.000 description 9
- 239000011782 vitamin Substances 0.000 description 9
- 150000003722 vitamin derivatives Chemical class 0.000 description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 8
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- 235000018102 proteins Nutrition 0.000 description 8
- 102000004169 proteins and genes Human genes 0.000 description 8
- 150000003839 salts Chemical class 0.000 description 8
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 7
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 7
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- -1 calcium phytates Chemical class 0.000 description 7
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 7
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- 239000003446 ligand Substances 0.000 description 1
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 229940049920 malate Drugs 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000011785 micronutrient Substances 0.000 description 1
- 235000013369 micronutrients Nutrition 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 229920001206 natural gum Polymers 0.000 description 1
- 239000012875 nonionic emulsifier Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 229940099990 ogen Drugs 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000007968 orange flavor Substances 0.000 description 1
- 210000003463 organelle Anatomy 0.000 description 1
- 210000000963 osteoblast Anatomy 0.000 description 1
- 210000002997 osteoclast Anatomy 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 230000037081 physical activity Effects 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229950008882 polysorbate Drugs 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- YUGCAAVRZWBXEQ-WHTXLNIXSA-N previtamin D3 Chemical compound C=1([C@@H]2CC[C@@H]([C@]2(CCC=1)C)[C@H](C)CCCC(C)C)\C=C/C1=C(C)CC[C@H](O)C1 YUGCAAVRZWBXEQ-WHTXLNIXSA-N 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000021251 pulses Nutrition 0.000 description 1
- 150000003214 pyranose derivatives Chemical group 0.000 description 1
- 230000009103 reabsorption Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 238000012958 reprocessing Methods 0.000 description 1
- QEVHRUUCFGRFIF-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C(C5=CC=C(OC)C=C5N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 QEVHRUUCFGRFIF-MDEJGZGSSA-N 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- IOVGROKTTNBUGK-SJCJKPOMSA-N ritodrine Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJCJKPOMSA-N 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 235000021309 simple sugar Nutrition 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 description 1
- 210000004894 snout Anatomy 0.000 description 1
- 229960001790 sodium citrate Drugs 0.000 description 1
- 229960000999 sodium citrate dihydrate Drugs 0.000 description 1
- YLYURHSBPLOMRT-UHFFFAOYSA-M sodium;2-hydroxypropane-1,2,3-tricarboxylic acid;benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1.OC(=O)CC(O)(C(O)=O)CC(O)=O YLYURHSBPLOMRT-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 150000003398 sorbic acids Chemical class 0.000 description 1
- 235000019614 sour taste Nutrition 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 235000019630 tart taste sensations Nutrition 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 229940035339 tri-chlor Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- ACRHGVZLZCYCME-UHFFFAOYSA-K trisodium 2-hydroxypropane-1,2,3-tricarboxylate 2-hydroxypropane-1,2,3-tricarboxylic acid 2-hydroxypropanoic acid Chemical compound C(C(O)C)(=O)O.C(CC(O)(C(=O)O)CC(=O)O)(=O)O.C(CC(O)(C(=O)[O-])CC(=O)[O-])(=O)[O-].[Na+].[Na+].[Na+] ACRHGVZLZCYCME-UHFFFAOYSA-K 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 230000000450 urinary calcium excretion Effects 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 235000020799 vitamin D status Nutrition 0.000 description 1
- 235000001892 vitamin D2 Nutrition 0.000 description 1
- 239000011653 vitamin D2 Substances 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/418,729 US5609897A (en) | 1995-04-07 | 1995-04-07 | Powdered beverage concentrate or additive fortified with calcium and vitamin D |
| US08/418,393 | 1995-04-07 | ||
| US08/418,729 | 1995-04-07 | ||
| US08/418,393 US5698222A (en) | 1995-04-07 | 1995-04-07 | Calcium supplement |
| US08/418,391 US5597595A (en) | 1995-04-07 | 1995-04-07 | Low pH beverage fortified with calcium and vitamin D |
| US08/418,391 | 1995-04-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2217264A1 true CA2217264A1 (en) | 1996-10-10 |
Family
ID=27411186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002217264A Abandoned CA2217264A1 (en) | 1995-04-07 | 1996-04-04 | Calcium supplements and calcium containing beverages comprising vitamin d |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0818957A2 (de) |
| JP (1) | JPH11503023A (de) |
| AU (1) | AU715227B2 (de) |
| CA (1) | CA2217264A1 (de) |
| MX (1) | MX9707584A (de) |
| NO (1) | NO974540L (de) |
| NZ (1) | NZ306211A (de) |
| WO (1) | WO1996031130A2 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE253921T1 (de) * | 1991-05-06 | 2003-11-15 | Procter & Gamble | Kombinationen aus calzium und vitamin d |
| US5696463A (en) * | 1993-11-02 | 1997-12-09 | Hyundai Electronics Industries Co., Ltd. | Address transition detecting circuit which generates constant pulse width signal |
| FR2760639B1 (fr) * | 1997-03-14 | 2000-09-22 | Innothera Lab Sa | Association therapeutique mineralo-vitaminique sous forme de preparation unitaire liquide buvable |
| US5855936A (en) * | 1997-03-21 | 1999-01-05 | Nestec S.A. | Food fortification |
| US5928691A (en) * | 1997-05-01 | 1999-07-27 | Nestec S.A. | Calcium complex and a process of making a food fortified with calcium |
| GB9709082D0 (en) | 1997-05-06 | 1997-06-25 | Ciba Geigy Ag | Organic compositions |
| GB9906009D0 (en) * | 1999-03-16 | 1999-05-12 | Nycomed Pharma As | Product |
| US6261610B1 (en) * | 1999-09-24 | 2001-07-17 | Nestec S.A. | Calcium-magnesium fortified water, juices, beverages and other liquid food products and process of making |
| MY140883A (en) * | 2002-12-17 | 2010-01-29 | Nestec Sa | Nutritional formula comprising l (+) lactic acid |
| CN2736752Y (zh) * | 2004-07-30 | 2005-10-26 | 北京博奥生物芯片有限责任公司 | 一种用于提取药物残留的样品制备仪 |
| SG169979A1 (en) * | 2006-02-17 | 2011-04-29 | Viridis Pharmaceutical Ltd | Accelerating agent of calcium absorption |
| JP5619334B2 (ja) * | 2006-06-14 | 2014-11-05 | 允聖 崔 | 骨強化剤 |
| JP4768797B2 (ja) * | 2008-11-12 | 2011-09-07 | 株式会社 伊藤園 | ビタミンｃ含有無糖炭酸飲料 |
| ES2387973B1 (es) | 2011-03-18 | 2013-10-01 | Dr Healthcare España, S. L. | Composiciones tópicas que contienen diaminooxidasa para el tratamiento o la prevención de enfermedades asociadas a un nivel de histamina elevada que comportan un aumento del dolor. |
| ES2388166B1 (es) | 2011-03-18 | 2013-10-01 | Dr Healthcare España, S. L. | Alimentos funcionales que contienen diaminooxidasa y sus usos. |
| US20130040036A1 (en) * | 2011-08-12 | 2013-02-14 | Bary Lyn Zeller | Shelf Stable, Low Water Liquid Beverage Concentrates And Methods Of Making The Same |
| WO2013152852A1 (en) * | 2012-04-10 | 2013-10-17 | Alpinia Laudanum Institute Of Phytopharmaceutical Sciences Ag | Wet granulation process and granulate material comprising arabic gum |
| ES2426539B1 (es) | 2012-04-18 | 2014-09-09 | Dr Healthcare España, S. L. | Uso de la diaminooxidasa para el tratamiento o la prevención del trastorno por deficit de atencion con hiperactividad (adhd) |
| US11013248B2 (en) | 2012-05-25 | 2021-05-25 | Kraft Foods Group Brands Llc | Shelf stable, concentrated, liquid flavorings and methods of preparing beverages with the concentrated liquid flavorings |
| EP2818176A1 (de) * | 2013-06-27 | 2014-12-31 | Virbac | Zusammensetzung zur Behandlung progressiver Nierenkrankheiten |
| IT201700099690A1 (it) * | 2017-09-06 | 2019-03-06 | Abiogen Pharma Spa | Composizione per l’integrazione di calcio |
| US11638439B2 (en) * | 2018-05-21 | 2023-05-02 | Agthia | Vitamin D-fortified water and method of manufacturing thereof |
| US11661363B2 (en) * | 2021-05-24 | 2023-05-30 | Heart Water, L.L.C. | Rainwater processing system and processing steps for producing potable functional water |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB590809A (en) * | 1944-03-04 | 1947-07-29 | Nat Oil Prod Co | Improvements in or relating to vitamin compositions and the manufacture thereof |
| DE1123084B (de) * | 1957-11-12 | 1962-02-01 | Camp Sea Food Company Van | Verfahren zur Herstellung eines Vitaminpulvers durch Emulgieren eines ein oelloesliches Vitamin enthaltenden OElkonzentrats |
| GB1118606A (en) * | 1966-04-01 | 1968-07-03 | Erskine Henry Muton | Compositions for the treatment of haemorrhoids |
| US4497800A (en) * | 1982-07-06 | 1985-02-05 | Mead Johnson & Company | Stable liquid diet composition |
| EP0102663A1 (de) * | 1982-08-10 | 1984-03-14 | Van Melle Nederland B.V. | Vitamine und/oder Mineralien und gegebenenfalls weitere Bestandteile enthaltendes ergänzendes Nahrungsmittel und Verfahren zur Herstellung desselben |
| JPH0748991B2 (ja) * | 1984-08-29 | 1995-05-31 | 日本油脂株式会社 | 経管栄養組成物 |
| JPS62232362A (ja) * | 1986-04-01 | 1987-10-12 | Ajinomoto Co Inc | 炭酸飲料 |
| GB8622025D0 (en) * | 1986-09-12 | 1986-10-22 | Beecham Group Plc | Composition |
| JP2751161B2 (ja) * | 1986-10-13 | 1998-05-18 | 味の素株式会社 | 栄養組成物 |
| IL88961A (en) * | 1988-01-29 | 1992-07-15 | Basf Ag | Stable mixtures containing oxidation-sensitive compounds |
| FI94715C (fi) * | 1991-01-28 | 1995-10-25 | Steel Joint Ltd Oy | Eläinten rehujen lisäaineena, eläinten kasvun edistämiseen sekä luuston ja kudosten voimistamiseen käytettävä seos |
| AU651738B2 (en) * | 1991-10-07 | 1994-07-28 | Otsuka Pharmaceutical Factory, Inc. | Enteral preparation for cancer therapy |
| US5438042B1 (en) * | 1993-10-08 | 1997-08-26 | Sandoz Nutrition Ltd | Enteral nutritional composition having amino acid profile |
| US5480661A (en) * | 1994-05-23 | 1996-01-02 | Consolidated Flavor Corporation | Vitamin A and D additive for milk products |
-
1996
- 1996-04-04 AU AU54415/96A patent/AU715227B2/en not_active Ceased
- 1996-04-04 CA CA002217264A patent/CA2217264A1/en not_active Abandoned
- 1996-04-04 NZ NZ306211A patent/NZ306211A/en unknown
- 1996-04-04 MX MX9707584A patent/MX9707584A/es not_active IP Right Cessation
- 1996-04-04 EP EP96911563A patent/EP0818957A2/de not_active Withdrawn
- 1996-04-04 JP JP8530463A patent/JPH11503023A/ja active Pending
- 1996-04-04 WO PCT/US1996/004601 patent/WO1996031130A2/en not_active Application Discontinuation
-
1997
- 1997-10-01 NO NO974540A patent/NO974540L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0818957A2 (de) | 1998-01-21 |
| NO974540D0 (no) | 1997-10-01 |
| WO1996031130A2 (en) | 1996-10-10 |
| NZ306211A (en) | 1998-08-26 |
| MX9707584A (es) | 1998-02-28 |
| NO974540L (no) | 1997-12-08 |
| AU5441596A (en) | 1996-10-23 |
| WO1996031130A3 (en) | 1997-01-03 |
| AU715227B2 (en) | 2000-01-20 |
| JPH11503023A (ja) | 1999-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |