CA2207289A1 - Colles tissulaires adjuventees et non adjuventees, procedes de production et d'utilisation - Google Patents

Colles tissulaires adjuventees et non adjuventees, procedes de production et d'utilisation

Info

Publication number
CA2207289A1
CA2207289A1 CA002207289A CA2207289A CA2207289A1 CA 2207289 A1 CA2207289 A1 CA 2207289A1 CA 002207289 A CA002207289 A CA 002207289A CA 2207289 A CA2207289 A CA 2207289A CA 2207289 A1 CA2207289 A1 CA 2207289A1
Authority
CA
Canada
Prior art keywords
supplemented
production
methods
tissue sealants
unsupplemented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002207289A
Other languages
English (en)
Other versions
CA2207289C (fr
Inventor
Hernan A. Nunez
William Nash Drohan
Wilson Hales Burgess
Howard P. Greisler
Jeffrey O. Hollinger
Carlos I. Lasa, Jr.
Thomas Maciag
Martin James Macphee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American National Red Cross
Loyola University Chicago
US Department of Army
Original Assignee
The American National Red Cross
Hernan A. Nunez
William Nash Drohan
Wilson Hales Burgess
Howard P. Greisler
Jeffrey O. Hollinger
Carlos I. Lasa, Jr.
Thomas Maciag
Martin James Macphee
Loyola University Of Chicago
United States Of America As Represented By The Secretary Of The Army
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The American National Red Cross, Hernan A. Nunez, William Nash Drohan, Wilson Hales Burgess, Howard P. Greisler, Jeffrey O. Hollinger, Carlos I. Lasa, Jr., Thomas Maciag, Martin James Macphee, Loyola University Of Chicago, United States Of America As Represented By The Secretary Of The Army filed Critical The American National Red Cross
Publication of CA2207289A1 publication Critical patent/CA2207289A1/fr
Application granted granted Critical
Publication of CA2207289C publication Critical patent/CA2207289C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0036—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002207289A 1994-12-07 1995-12-06 Colles tissulaires adjuventees et non adjuventees, procedes de production et d'utilisation Expired - Lifetime CA2207289C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35100694A 1994-12-07 1994-12-07
US08/351,006 1994-12-07
PCT/US1995/015876 WO1996017633A1 (fr) 1994-12-07 1995-12-06 Colles tissulaires adjuventees et non adjuventees, procedes de production et d'utilisation

Publications (2)

Publication Number Publication Date
CA2207289A1 true CA2207289A1 (fr) 1996-06-13
CA2207289C CA2207289C (fr) 2005-04-12

Family

ID=23379191

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002207289A Expired - Lifetime CA2207289C (fr) 1994-12-07 1995-12-06 Colles tissulaires adjuventees et non adjuventees, procedes de production et d'utilisation

Country Status (5)

Country Link
EP (1) EP0796115A1 (fr)
JP (1) JP4223548B2 (fr)
AU (1) AU717906B2 (fr)
CA (1) CA2207289C (fr)
WO (1) WO1996017633A1 (fr)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054122A (en) 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US7196054B1 (en) 1990-11-27 2007-03-27 The American National Red Cross Methods for treating wound tissue and forming a supplemented fibrin matrix
EP0869804A4 (fr) * 1995-06-07 2001-08-16 American Nat Red Cross Produits d'obturation tissulaires completes et non completes, leurs procedes de production et d'utilisation
AU7977298A (en) 1997-06-18 1999-01-04 Cohesion Technologies, Inc. Compositions containing thrombin and microfibrillar collagen, and methods for preparation and use thereof
AT407117B (de) * 1997-09-19 2000-12-27 Immuno Ag Fibrinschwamm
US6503527B1 (en) * 1997-11-17 2003-01-07 Haemacure Corporation Fibrin sealants or adhesives comprising a hyaluronic acid derivative material
US6056970A (en) * 1998-05-07 2000-05-02 Genzyme Corporation Compositions comprising hemostatic compounds and bioabsorbable polymers
US7241730B2 (en) 1998-08-27 2007-07-10 Universitat Zurich Enzyme-mediated modification of fibrin for tissue engineering: fibrin formulations with peptides
US7601685B2 (en) 1998-08-27 2009-10-13 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
JP2003026673A (ja) * 1999-03-05 2003-01-29 Asahi Kasei Corp 骨形成促進剤
JP3576063B2 (ja) 2000-02-22 2004-10-13 株式会社ホギメディカル 凝固蛋白質を含む可溶性創傷治癒止血セルロース繊維とその製造方法
WO2001097872A1 (fr) * 2000-06-22 2001-12-27 Austin Sam L Compositions bioadhesives et methodes de preparation et d'utilisation
US6921532B1 (en) 2000-06-22 2005-07-26 Spinal Restoration, Inc. Biological Bioadhesive composition and methods of preparation and use
US7247609B2 (en) 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
US8403923B2 (en) 2004-10-29 2013-03-26 Spinal Restoration, Inc. Injection of fibrin sealant in the absence of corticosteroids in spinal applications
US8419722B2 (en) 2004-10-29 2013-04-16 Spinal Restoration, Inc. Apparatus and method for injection of fibrin sealant in spinal applications
US7597687B2 (en) 2004-10-29 2009-10-06 Spinal Restoration, Inc. Injection of fibrin sealant including an anesthetic in spinal applications
US8206448B2 (en) 2004-10-29 2012-06-26 Spinal Restoration, Inc. Injection of fibrin sealant using reconstituted components in spinal applications
US8124075B2 (en) 2004-07-16 2012-02-28 Spinal Restoration, Inc. Enhanced biological autologous tissue adhesive composition and methods of preparation and use
US9358318B2 (en) 2004-10-20 2016-06-07 Ethicon, Inc. Method of making a reinforced absorbable multilayered hemostatic wound dressing
DK1809343T3 (da) * 2004-10-20 2012-11-26 Ethicon Inc Forstærket absorberbar hæmostatisk flerlagssårforbinding samt fremstillingsfremgangsmåde
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
WO2006073711A2 (fr) 2005-01-06 2006-07-13 Kuros Biosurgery Ag Traitement local des deficits osseux
US8367405B2 (en) 2005-04-12 2013-02-05 Mesoblast, Inc. Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase
US7429241B2 (en) 2005-09-29 2008-09-30 Codman & Shurtleff, Inc. Dural graft and method of preparing the same
KR100701552B1 (ko) * 2006-06-23 2007-03-30 한국과학기술연구원 압축기체를 이용한 필라멘트 및 시트 형태의 생분해성폴리에스테르 고분자 소재의 제조방법
GB0623607D0 (en) * 2006-11-27 2007-01-03 Haemostatix Ltd Tissue adhesive
MX2009006369A (es) 2006-12-15 2010-02-24 Lifebond Ltd Apositos y selladores hemostaticos de gelatina-transglutaminasa.
CA2685807C (fr) 2007-04-13 2016-04-12 Kuros Biosurgery Ag Agent de scellement tissulaire polymere
KR20170045382A (ko) 2007-08-06 2017-04-26 메소블라스트, 아이엔씨. 생체 내에서 결합 조직을 생성, 복구 및/또는 유지하는 방법
JP2012512812A (ja) 2007-12-28 2012-06-07 クロス・バイオサージェリー・アクチェンゲゼルシャフト フィブリンフォームに組込まれたｐｄｇｆ融合タンパク質
EP2487206A3 (fr) 2008-06-18 2012-11-28 Lifebond Ltd Compositions réticulables à base de gélatine
CN104678106B (zh) 2008-08-18 2016-12-07 中胚有限公司 单克隆抗体stro-4
US9827205B2 (en) 2008-12-12 2017-11-28 Mallinckrodt Pharma Ip Trading D.A.C. Dry powder fibrin sealant
JP5796860B2 (ja) 2009-12-22 2015-10-21 ライフボンド リミテッドＬｉｆｅｂｏｎｄ Ｌｔｄ 架橋マトリックスの特性を調節するための酵素的架橋剤の改変
WO2011083154A1 (fr) 2010-01-08 2011-07-14 Profibrix Bv Adhésif de fibrine en poudre sèche
CA2807012A1 (fr) 2010-08-05 2012-02-09 Lifebond Ltd. Pansements et adhesifs contenant des compositions seches
EP2686027B1 (fr) 2011-03-16 2021-05-05 Kuros Biosurgery AG Formulation pharmaceutique destinée à être utilisée dans une fusion des vertèbres
US8999376B2 (en) * 2012-02-03 2015-04-07 Xcede Technologies, Inc. Tissue patch
GB201400292D0 (en) 2014-01-08 2014-02-26 Haemostatix Ltd Peptide dendrimers and agents
US10660945B2 (en) 2015-08-07 2020-05-26 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
CA2994959A1 (fr) 2015-08-07 2017-02-16 Xcede Technologies, Inc. Compositions adhesives et procedes associes
US10751444B2 (en) 2015-08-07 2020-08-25 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
US9833538B2 (en) 2015-08-07 2017-12-05 Xcede Technologies, Inc. Adhesive compositions and related methods
KR101878769B1 (ko) 2017-04-03 2018-08-16 조석형 저분자 cm-1,3-베타글루칸 칼슘염 분말 지혈제
DE102017126149A1 (de) * 2017-11-08 2019-05-09 Johannes Gutenberg-Universität Mainz Wirkstoffhaltiger Schichtverbund sowie Verfahren zu dessen Herstellung
JP2022502482A (ja) * 2018-09-17 2022-01-11 ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム 骨損傷を治療するための組成物及び方法
JP2022554153A (ja) * 2019-10-23 2022-12-28 フィブリアント・ベスローテン・フェンノートシャップ 抗微生物剤および抗微生物治療用アジュバントとしてのフィブリノゲン

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4706662A (en) * 1981-12-11 1987-11-17 Johnson & Johnson Products, Inc. Film dressing with fabric backing
FR2589737A1 (fr) * 1985-11-12 1987-05-15 Dow Corning Sa Procedes de fabrication de pansements
EP1142581A3 (fr) * 1990-11-27 2002-09-11 American National Red Cross Compositions contenant un agent de scellement tissulaire et des facteurs de croissance, qui accélérent la cicatrisation
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
GB9206509D0 (en) * 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
WO1994020133A1 (fr) * 1993-03-12 1994-09-15 The American National Red Cross Substances de scellement tissulaire avec et sans complement, leurs procedes de production et leur utilisation

Also Published As

Publication number Publication date
AU717906B2 (en) 2000-04-06
AU4510096A (en) 1996-06-26
EP0796115A1 (fr) 1997-09-24
JPH10510183A (ja) 1998-10-06
WO1996017633A1 (fr) 1996-06-13
JP4223548B2 (ja) 2009-02-12
CA2207289C (fr) 2005-04-12

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Effective date: 20151207