CA2203791A1 - Analogues synthetiques d'acides gras polyinsatures - Google Patents

Analogues synthetiques d'acides gras polyinsatures

Info

Publication number
CA2203791A1
CA2203791A1 CA 2203791 CA2203791A CA2203791A1 CA 2203791 A1 CA2203791 A1 CA 2203791A1 CA 2203791 CA2203791 CA 2203791 CA 2203791 A CA2203791 A CA 2203791A CA 2203791 A1 CA2203791 A1 CA 2203791A1
Authority
CA
Canada
Prior art keywords
acid
otbu
glycine
tfa
fatty acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2203791
Other languages
English (en)
Inventor
Fred Widmer
Paul Adam Schober
Merilyn Joy Sleigh
Antonio Ferrante
Alfred Poulos
Deborah Ann Rathjen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Children Youth and Womens Health Service Inc
Teva Pharmaceuticals Australia Pty Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPM9065A external-priority patent/AUPM906594A0/en
Application filed by Individual filed Critical Individual
Publication of CA2203791A1 publication Critical patent/CA2203791A1/fr
Abandoned legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne des composés d'acides gras polyinsaturés présentant une activité antipaludéenne et/ou neutrophilo-stimulante, ou une activité anti-inflammatoire. Ces acides gras polyinsaturés, qui contiennent une chaîne de 16 à 26 atomes de carbones et 3 à 6 bandes doubles, sont couplés en covalence au groupe carboxylique d'un acide aminé. Dans une réalisation préférée, l'acide gras contient de 18 à 22 atomes de carbones et l'acide aminé est l'acide aminoacétique ou l'acide aspartique. Les composés préférés sont acide .gamma.-linoléïque - acide aminoacétique, acide .alpha.-linoléïque - acide aminoacétique, acide arachidonique - acide aminoacétique, acide docosahexaénoïque - acide aminoacétique, acide eicosapentaénoïque - acide aminoacétique, acide .gamma.-linoléïque - acide aspartique, acide .alpha.-linoléïque - acide aspartique, acide arachidonique - acide aspartique, acide eicosapentaénoïque - acide aspartique et acide docosahexaénoïque - acide aspartique.
CA 2203791 1994-10-26 1995-10-25 Analogues synthetiques d'acides gras polyinsatures Abandoned CA2203791A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPM9065A AUPM906594A0 (en) 1994-10-26 1994-10-26 Synthetic polyunsaturated fatty acid analogues
AUPM9065 1994-10-26
PCT/AU1995/000717 WO1996013507A1 (fr) 1994-10-26 1995-10-25 Analogues synthetiques d'acides gras polyinsatures

Publications (1)

Publication Number Publication Date
CA2203791A1 true CA2203791A1 (fr) 1996-05-09

Family

ID=29402800

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2203791 Abandoned CA2203791A1 (fr) 1994-10-26 1995-10-25 Analogues synthetiques d'acides gras polyinsatures

Country Status (1)

Country Link
CA (1) CA2203791A1 (fr)

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