CA2195246A1 - Growth differentiation factor-12 - Google Patents
Growth differentiation factor-12Info
- Publication number
- CA2195246A1 CA2195246A1 CA002195246A CA2195246A CA2195246A1 CA 2195246 A1 CA2195246 A1 CA 2195246A1 CA 002195246 A CA002195246 A CA 002195246A CA 2195246 A CA2195246 A CA 2195246A CA 2195246 A1 CA2195246 A1 CA 2195246A1
- Authority
- CA
- Canada
- Prior art keywords
- gdf
- cell
- leu
- vector
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
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- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
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- Biochemistry (AREA)
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- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/274,215 US5831054A (en) | 1994-07-13 | 1994-07-13 | Polynucleotide encoding growth differentiation factor-12 |
| US08/274,215 | 1994-07-13 | ||
| US31137094A | 1994-09-26 | 1994-09-26 | |
| US08/311,370 | 1994-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2195246A1 true CA2195246A1 (en) | 1996-02-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002195246A Abandoned CA2195246A1 (en) | 1994-07-13 | 1995-07-12 | Growth differentiation factor-12 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5929213A (ja) |
| EP (1) | EP0770089B1 (ja) |
| JP (1) | JPH10503362A (ja) |
| AT (1) | ATE196147T1 (ja) |
| CA (1) | CA2195246A1 (ja) |
| DE (1) | DE69518760T2 (ja) |
| DK (1) | DK0770089T3 (ja) |
| ES (1) | ES2151607T3 (ja) |
| GR (1) | GR3034772T3 (ja) |
| PT (1) | PT770089E (ja) |
| WO (1) | WO1996002559A1 (ja) |
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| US5846770A (en) * | 1994-11-22 | 1998-12-08 | Genetics Institute, Inc. | DNA molecules encoding human chordin |
| US5965403A (en) | 1996-09-18 | 1999-10-12 | Genetics Institute, Inc. | Nucleic acids encoding bone morphogenic protein-16 (BMP-16) |
| US20020052026A1 (en) | 1997-10-08 | 2002-05-02 | Steven M. Vicik | Methods of refolding proteins |
| US6027917A (en) | 1997-12-10 | 2000-02-22 | Genetics Institute, Inc. | Bone morphogenetic protein (BMP)-17 and BMP-18 compositions |
| US6727224B1 (en) | 1999-02-01 | 2004-04-27 | Genetics Institute, Llc. | Methods and compositions for healing and repair of articular cartilage |
| CA2394576A1 (en) * | 1999-12-15 | 2001-06-21 | Research Development Foundation | Betaglycan as an inhibin receptor and uses thereof |
| TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
| RU2363478C2 (ru) | 2003-09-12 | 2009-08-10 | Вайет | Инъецируемые стержни из фосфата кальция для доставки остеогенных белков |
| AU2005247871A1 (en) | 2004-04-27 | 2005-12-08 | Research Development Foundation | Antagonism of TGF-beta superfamily receptor signaling |
| US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
| US8147860B2 (en) | 2005-12-06 | 2012-04-03 | Etex Corporation | Porous calcium phosphate bone material |
| WO2007092622A2 (en) | 2006-02-09 | 2007-08-16 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating bone |
| ES2664229T3 (es) | 2006-06-30 | 2018-04-18 | Biomimetic Therapeutics, Llc | Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador |
| US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| US8524265B2 (en) | 2006-08-17 | 2013-09-03 | Warsaw Orthopedic, Inc. | Medical implant sheets useful for tissue regeneration |
| NZ591338A (en) | 2008-09-09 | 2013-02-22 | Biomimetic Therapeutics Inc | Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries |
| US8609127B2 (en) | 2009-04-03 | 2013-12-17 | Warsaw Orthopedic, Inc. | Medical implant with bioactive material and method of making the medical implant |
| WO2010144696A1 (en) | 2009-06-11 | 2010-12-16 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
| WO2011103598A1 (en) | 2010-02-22 | 2011-08-25 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods for the treatment of tendinopathies |
| US10034945B2 (en) | 2012-07-13 | 2018-07-31 | Trustees Of Tufts College | Silk powder compaction for production of constructs with high mechanical strength and stiffness |
| JP7025021B2 (ja) | 2015-10-26 | 2022-02-24 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 還元多糖および酸化多糖ならびにそれらの使用の方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE188996T1 (de) * | 1992-02-12 | 2000-02-15 | Bioph Biotech Entw Pharm Gmbh | Dna-sequenzen kodierend für neuartige wachstums- /differentierungsfaktoren |
-
1995
- 1995-07-12 DK DK95928062T patent/DK0770089T3/da active
- 1995-07-12 DE DE69518760T patent/DE69518760T2/de not_active Expired - Fee Related
- 1995-07-12 WO PCT/US1995/008745 patent/WO1996002559A1/en active IP Right Grant
- 1995-07-12 ES ES95928062T patent/ES2151607T3/es not_active Expired - Lifetime
- 1995-07-12 US US08/765,662 patent/US5929213A/en not_active Expired - Fee Related
- 1995-07-12 CA CA002195246A patent/CA2195246A1/en not_active Abandoned
- 1995-07-12 JP JP7523725A patent/JPH10503362A/ja active Pending
- 1995-07-12 EP EP95928062A patent/EP0770089B1/en not_active Expired - Lifetime
- 1995-07-12 PT PT95928062T patent/PT770089E/pt unknown
- 1995-07-12 AT AT95928062T patent/ATE196147T1/de not_active IP Right Cessation
-
2000
- 2000-11-07 GR GR20000402461T patent/GR3034772T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0770089A1 (en) | 1997-05-02 |
| PT770089E (pt) | 2001-02-28 |
| WO1996002559A1 (en) | 1996-02-01 |
| JPH10503362A (ja) | 1998-03-31 |
| DE69518760T2 (de) | 2001-05-23 |
| ES2151607T3 (es) | 2001-01-01 |
| EP0770089B1 (en) | 2000-09-06 |
| DK0770089T3 (da) | 2000-10-23 |
| EP0770089A4 (en) | 1997-06-18 |
| US5929213A (en) | 1999-07-27 |
| ATE196147T1 (de) | 2000-09-15 |
| GR3034772T3 (en) | 2001-02-28 |
| DE69518760D1 (de) | 2000-10-12 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |