CA2187336A1

CA2187336A1 - Pharmaceutical formulations for treating japanese cedar pollen allergy

Pharmaceutical formulations for treating japanese cedar pollen allergy

Info

Publication number: CA2187336A1
Authority: CA; Canada
Prior art keywords: seq; cji; peptide; peptides; gly
Prior art date: 1994-04-08
Legal status : Abandoned

Application number

CA002187336A

Other languages

English (en)

French (fr)

Inventor

Henry M. Franzen

Stephen Palmer Powers

Mei-Chang Kuo

Sean Evans

Ze'ev Shaked

Xian Chen

Current Assignee

Individual

Original Assignee

Immulogic Pharmaceutical Corp

Priority date

1994-04-08

Filing date

1995-04-06

Publication date

1995-10-19

1995-04-06 Application filed by Immulogic Pharmaceutical Corp filed Critical Immulogic Pharmaceutical Corp

1995-10-19 Publication of CA2187336A1 publication Critical patent/CA2187336A1/en

Status Abandoned legal-status Critical Current

Links

208000035285 Allergic Seasonal Rhinitis Diseases 0.000 title abstract description 6
206010048908 Seasonal allergy Diseases 0.000 title abstract description 6
201000004338 pollen allergy Diseases 0.000 title abstract description 4
240000005109 Cryptomeria japonica Species 0.000 title description 5
239000008194 pharmaceutical composition Substances 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 319
102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 146
241000218692 Cryptomeria Species 0.000 claims abstract description 49
230000001225 therapeutic effect Effects 0.000 claims abstract description 30
239000013573 pollen allergen Substances 0.000 claims abstract description 23
238000011282 treatment Methods 0.000 claims abstract description 19
239000000203 mixture Substances 0.000 claims abstract description 17
208000026935 allergic disease Diseases 0.000 claims abstract description 14
206010020751 Hypersensitivity Diseases 0.000 claims abstract description 12
230000007815 allergy Effects 0.000 claims abstract description 12
238000009472 formulation Methods 0.000 claims abstract description 11
210000001744 T-lymphocyte Anatomy 0.000 claims description 87
239000013566 allergen Substances 0.000 claims description 25
238000000034 method Methods 0.000 claims description 25
239000003814 drug Substances 0.000 claims description 17
150000002500 ions Chemical class 0.000 claims description 10
239000000546 pharmaceutical excipient Substances 0.000 claims description 9
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 8
229930195725 Mannitol Natural products 0.000 claims description 8
230000000694 effects Effects 0.000 claims description 8
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230000035945 sensitivity Effects 0.000 claims description 7
239000001488 sodium phosphate Substances 0.000 claims description 7
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RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims description 7
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125000003275 alpha amino acid group Chemical group 0.000 claims 1
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