CA2167840A1 - Linked linear amplification of nucleic acids - Google Patents

Linked linear amplification of nucleic acids

Info

Publication number
CA2167840A1
CA2167840A1 CA002167840A CA2167840A CA2167840A1 CA 2167840 A1 CA2167840 A1 CA 2167840A1 CA 002167840 A CA002167840 A CA 002167840A CA 2167840 A CA2167840 A CA 2167840A CA 2167840 A1 CA2167840 A1 CA 2167840A1
Authority
CA
Canada
Prior art keywords
primers
primer extension
primer
nucleic acid
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002167840A
Other languages
English (en)
French (fr)
Inventor
Robert Bruce Wallace
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2167840A1 publication Critical patent/CA2167840A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002167840A 1993-07-23 1994-07-25 Linked linear amplification of nucleic acids Abandoned CA2167840A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9544293A 1993-07-23 1993-07-23
US08/095,442 1993-07-23

Publications (1)

Publication Number Publication Date
CA2167840A1 true CA2167840A1 (en) 1995-02-02

Family

ID=22252059

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002167840A Abandoned CA2167840A1 (en) 1993-07-23 1994-07-25 Linked linear amplification of nucleic acids

Country Status (5)

Country Link
EP (1) EP0710296A4 (de)
JP (1) JPH09500539A (de)
CN (1) CN1127533A (de)
CA (1) CA2167840A1 (de)
WO (1) WO1995003432A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335184B1 (en) 1993-07-23 2002-01-01 Bio-Rad Laboratories, Inc. Linked linear amplification of nucleic acids
CN1117871C (zh) * 1995-06-07 2003-08-13 伯乐实验有限公司 核酸的衔接线性扩增
EP0862656B1 (de) 1995-11-21 2001-03-07 Yale University Unimolekulare segmentamplifikation und bestimmung
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
EP1098996A1 (de) 1998-07-20 2001-05-16 Yale University Verfahren zum nachweis von nukleinsäuren unter verwendung zielgerichteter ligation von zweiteiligen primern
JP2002525049A (ja) 1998-09-15 2002-08-13 イェール ユニバーシティ ローリングサークル増幅を用いる分子クローニング
EP1112385A1 (de) 1998-09-15 2001-07-04 Yale University Künstliche vektoren mit langen wiederholungssequenzen
US7205129B1 (en) * 2000-02-28 2007-04-17 Qiagen Gmbh Method for reducing artifacts in nucleic acid amplification
DE60130763T2 (de) 2000-06-30 2008-07-17 Qiagen Gmbh Signalamplifikation mit "lollipop"-hydridisierungsproben
US6573051B2 (en) 2001-03-09 2003-06-03 Molecular Staging, Inc. Open circle probes with intramolecular stem structures
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
ATE537251T1 (de) 2005-10-06 2011-12-15 Lucigen Corp Temperaturstabile virale polymerasen und verwendungsverfahren
EP3044326B1 (de) * 2013-09-13 2017-12-06 F. Hoffmann-La Roche AG Verwendung von oligo-dt-molekülen zur verhinderung der erzeugung von hochmolekularen pcr-produkten durch polya-träger

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
IE61148B1 (en) * 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
GB8920097D0 (en) * 1989-09-06 1989-10-18 Ici Plc Amplification processes

Also Published As

Publication number Publication date
CN1127533A (zh) 1996-07-24
EP0710296A1 (de) 1996-05-08
WO1995003432A1 (en) 1995-02-02
EP0710296A4 (de) 1999-05-26
JPH09500539A (ja) 1997-01-21

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead