CA2165281A1 - A stabilised phenylalanine ammmonia lyase - Google Patents

A stabilised phenylalanine ammmonia lyase

Info

Publication number
CA2165281A1
CA2165281A1 CA002165281A CA2165281A CA2165281A1 CA 2165281 A1 CA2165281 A1 CA 2165281A1 CA 002165281 A CA002165281 A CA 002165281A CA 2165281 A CA2165281 A CA 2165281A CA 2165281 A1 CA2165281 A1 CA 2165281A1
Authority
CA
Canada
Prior art keywords
pal
cell
enzyme preparation
amino acid
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002165281A
Other languages
English (en)
French (fr)
Inventor
Peter Eigtved
Ib Groth Clausen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2165281A1 publication Critical patent/CA2165281A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Lubricants (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002165281A 1993-06-25 1994-06-09 A stabilised phenylalanine ammmonia lyase Abandoned CA2165281A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93755A DK75593D0 (instruction) 1993-06-25 1993-06-25
DK0755/93 1993-06-25

Publications (1)

Publication Number Publication Date
CA2165281A1 true CA2165281A1 (en) 1995-01-05

Family

ID=8097168

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002165281A Abandoned CA2165281A1 (en) 1993-06-25 1994-06-09 A stabilised phenylalanine ammmonia lyase

Country Status (10)

Country Link
US (1) US5753487A (instruction)
EP (1) EP0703788B1 (instruction)
AT (1) ATE209044T1 (instruction)
AU (1) AU7067594A (instruction)
CA (1) CA2165281A1 (instruction)
DE (1) DE69429167T2 (instruction)
DK (2) DK75593D0 (instruction)
ES (1) ES2168297T3 (instruction)
PT (1) PT703788E (instruction)
WO (1) WO1995000171A1 (instruction)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6051020A (en) 1994-02-09 2000-04-18 Boston Scientific Technology, Inc. Bifurcated endoluminal prosthesis
ES2227611T3 (es) 1995-09-29 2005-04-01 Biomarin Pharmaceutical Inc Uso de heparinas para disminuir repuestas inflamatorias.
US5647368A (en) * 1996-02-28 1997-07-15 Xillix Technologies Corp. Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract
US6190883B1 (en) 1998-09-09 2001-02-20 Novo Nordisk A/S Method for the production of heterologous polypeptides in transformed yeast cells
US6368837B1 (en) 1999-08-06 2002-04-09 E. I. Du Pont Nemours And Company Bioproduction of para-hydroxycinnamic acid
US6521748B2 (en) 1999-08-06 2003-02-18 E. I. Du Pont De Nemours And Company Polynucleotide encoding a mutant Rhodotorula glutinis tyrosine ammonia lyase polypeptide
EP1372703A2 (en) * 2001-02-16 2004-01-02 Ibex Technologies Matrix stabilized enzyme crystals and methods of use
JP2008513027A (ja) * 2004-09-17 2008-05-01 バイオマリン ファーマシューティカル インコーポレイテッド フェニルアラニンアンモニアーリアーゼの改変体および化学的に修飾された改変体
US20090038023A1 (en) 2005-03-10 2009-02-05 Verenium Corporation Lyase Enzymes, Nucleic Acids Encoding Them and Methods For Making and Using Them
US20070122344A1 (en) 2005-09-02 2007-05-31 University Of Rochester Medical Center Office Of Technology Transfer Intraoperative determination of nerve location
US7534595B2 (en) * 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7531341B1 (en) 2006-06-12 2009-05-12 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US20080161744A1 (en) 2006-09-07 2008-07-03 University Of Rochester Medical Center Pre-And Intra-Operative Localization of Penile Sentinel Nodes
US7537923B2 (en) 2007-08-17 2009-05-26 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
US8406860B2 (en) 2008-01-25 2013-03-26 Novadaq Technologies Inc. Method for evaluating blush in myocardial tissue
US10219742B2 (en) 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
EP2687235A3 (en) 2008-05-02 2014-11-05 Novadaq Technologies Inc. Methods for production and use of substance-loaded erythrocytes (S-LES) for observation and treatment of microvascular hemodynamics
US9376659B2 (en) * 2008-07-24 2016-06-28 Arch Personal Care Products, L.P. Personal care composition containing yeast/polyphenol ferment extract
US20110201022A1 (en) * 2008-07-30 2011-08-18 Biomarin Pharmaceutical Inc. Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase
US10492671B2 (en) 2009-05-08 2019-12-03 Novadaq Technologies ULC Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest
US20130039898A1 (en) 2010-02-04 2013-02-14 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase variants and methods of using compositions thereof
AU2011272825A1 (en) 2010-06-30 2013-01-10 Codexis, Inc. Chemically modified carbonic anhydrases useful in carbon capture systems
WO2013190391A2 (en) 2012-06-21 2013-12-27 Novadaq Technologies Inc. Quantification and analysis of angiography and perfusion
EA034034B1 (ru) 2013-04-18 2019-12-20 Кодексис, Инк. Сконструированные полипептиды фенилаланин-аммиак-лиазы
HK1244873A1 (zh) 2014-09-29 2018-08-17 Novadaq Technologies Inc. 在自体荧光存在下生物材料中目标荧光团的成像
CA2963450A1 (en) 2014-10-09 2016-04-14 Novadaq Technologies Inc. Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography
EP3580609B1 (en) 2017-02-10 2023-05-24 Stryker European Operations Limited Open-field handheld fluorescence imaging systems and methods
MX2019009615A (es) 2017-02-13 2019-10-14 Codexis Inc Polipeptidos dise?ados de fenilalanina amonio liasa.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538003A (fr) * 1968-03-29 1973-01-31 Anvar Procédé pour l'obtention d'articles textiles porteurs d'enzymes
IT1096208B (it) * 1978-05-12 1985-08-26 Snam Progetti Composizione adatta alla riduzione del tenore di fenilalanina e metodo impiegante la stessa
FR2523445A1 (fr) * 1982-03-17 1983-09-23 Sanofi Sa Nouveaux conjugues associant, par liaison covalente, une enzyme et un anticorps, et associations medicamenteuses utilisant lesdits conjugues

Also Published As

Publication number Publication date
WO1995000171A1 (en) 1995-01-05
AU7067594A (en) 1995-01-17
PT703788E (pt) 2002-05-31
DE69429167T2 (de) 2002-07-04
EP0703788A1 (en) 1996-04-03
US5753487A (en) 1998-05-19
DK0703788T3 (da) 2002-05-21
DK75593D0 (instruction) 1993-06-25
EP0703788B1 (en) 2001-11-21
DE69429167D1 (de) 2002-01-03
ES2168297T3 (es) 2002-06-16
ATE209044T1 (de) 2001-12-15

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued
FZDE Discontinued

Effective date: 20050728