PT703788E - Fenilanina-amonio-liasa estabilizada - Google Patents
Fenilanina-amonio-liasa estabilizadaInfo
- Publication number
- PT703788E PT703788E PT94919559T PT94919559T PT703788E PT 703788 E PT703788 E PT 703788E PT 94919559 T PT94919559 T PT 94919559T PT 94919559 T PT94919559 T PT 94919559T PT 703788 E PT703788 E PT 703788E
- Authority
- PT
- Portugal
- Prior art keywords
- pct
- ammonia lyase
- phenylalanine ammonia
- amonyliasis
- phenylin
- Prior art date
Links
- 108700023158 Phenylalanine ammonia-lyases Proteins 0.000 abstract 3
- 238000007385 chemical modification Methods 0.000 abstract 1
- 239000003431 cross linking reagent Substances 0.000 abstract 1
- 238000012239 gene modification Methods 0.000 abstract 1
- 230000005017 genetic modification Effects 0.000 abstract 1
- 235000013617 genetically modified food Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000017854 proteolysis Effects 0.000 abstract 1
- 230000006641 stabilisation Effects 0.000 abstract 1
- 238000011105 stabilization Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Lubricants (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK93755A DK75593D0 (pt) | 1993-06-25 | 1993-06-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT703788E true PT703788E (pt) | 2002-05-31 |
Family
ID=8097168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT94919559T PT703788E (pt) | 1993-06-25 | 1994-06-09 | Fenilanina-amonio-liasa estabilizada |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5753487A (pt) |
| EP (1) | EP0703788B1 (pt) |
| AT (1) | ATE209044T1 (pt) |
| AU (1) | AU7067594A (pt) |
| CA (1) | CA2165281A1 (pt) |
| DE (1) | DE69429167T2 (pt) |
| DK (2) | DK75593D0 (pt) |
| ES (1) | ES2168297T3 (pt) |
| PT (1) | PT703788E (pt) |
| WO (1) | WO1995000171A1 (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU703394B2 (en) | 1995-09-29 | 1999-03-25 | Biomarin Pharmaceutical Inc. | Use of heparinases to decrease inflammatory responses |
| US5647368A (en) * | 1996-02-28 | 1997-07-15 | Xillix Technologies Corp. | Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract |
| US6190883B1 (en) | 1998-09-09 | 2001-02-20 | Novo Nordisk A/S | Method for the production of heterologous polypeptides in transformed yeast cells |
| US6368837B1 (en) | 1999-08-06 | 2002-04-09 | E. I. Du Pont Nemours And Company | Bioproduction of para-hydroxycinnamic acid |
| US6521748B2 (en) * | 1999-08-06 | 2003-02-18 | E. I. Du Pont De Nemours And Company | Polynucleotide encoding a mutant Rhodotorula glutinis tyrosine ammonia lyase polypeptide |
| EP1372703A2 (en) * | 2001-02-16 | 2004-01-02 | Ibex Technologies | Matrix stabilized enzyme crystals and methods of use |
| AU2005286763A1 (en) * | 2004-09-17 | 2006-03-30 | Biomarin Pharmaceutical, Inc. | Variants and chemically-modified variants of phenylalanine ammonia-lyase |
| WO2006099207A2 (en) | 2005-03-10 | 2006-09-21 | Diversa Corporation | Lyase enzymes, nucleic acids encoding them and methods for making and using them |
| US20070122344A1 (en) | 2005-09-02 | 2007-05-31 | University Of Rochester Medical Center Office Of Technology Transfer | Intraoperative determination of nerve location |
| US7531341B1 (en) | 2006-06-12 | 2009-05-12 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
| US7534595B2 (en) | 2006-06-12 | 2009-05-19 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
| US20080161744A1 (en) | 2006-09-07 | 2008-07-03 | University Of Rochester Medical Center | Pre-And Intra-Operative Localization of Penile Sentinel Nodes |
| US7537923B2 (en) * | 2007-08-17 | 2009-05-26 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof |
| US8406860B2 (en) | 2008-01-25 | 2013-03-26 | Novadaq Technologies Inc. | Method for evaluating blush in myocardial tissue |
| US10219742B2 (en) | 2008-04-14 | 2019-03-05 | Novadaq Technologies ULC | Locating and analyzing perforator flaps for plastic and reconstructive surgery |
| EP2285421B1 (en) | 2008-05-02 | 2018-04-11 | Novadaq Technologies ULC | Methods for production and use of substance-loaded erythrocytes for observation and treatment of microvascular hemodynamics |
| US9376659B2 (en) * | 2008-07-24 | 2016-06-28 | Arch Personal Care Products, L.P. | Personal care composition containing yeast/polyphenol ferment extract |
| WO2010014225A2 (en) | 2008-07-30 | 2010-02-04 | Biomarin Pharmaceutical Inc. | Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase |
| US10492671B2 (en) | 2009-05-08 | 2019-12-03 | Novadaq Technologies ULC | Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest |
| EP3025728B1 (en) | 2010-02-04 | 2018-08-08 | BioMarin Pharmaceutical Inc. | Method for purifying prokaryotic phenylalanine ammonia-lyase variants |
| US8354262B2 (en) | 2010-06-30 | 2013-01-15 | Codexis, Inc. | Chemically modified carbonic anhydrases useful in carbon capture systems |
| JP6028096B2 (ja) | 2012-06-21 | 2016-11-16 | ノバダック テクノロジーズ インコーポレイテッド | 血管造影及びかん流の定量化並びに解析手法 |
| NZ713396A (en) | 2013-04-18 | 2020-06-26 | Codexis Inc | Engineered phenylalanine ammonia lyase polypeptides |
| AU2015327665B2 (en) | 2014-09-29 | 2018-09-27 | Stryker European Operations Limited | Imaging a target fluorophore in a biological material in the presence of autofluorescence |
| JP6487544B2 (ja) | 2014-10-09 | 2019-03-20 | ノバダック テクノロジーズ ユーエルシー | 蛍光媒介光電式容積脈波記録法を用いた組織中の絶対血流の定量化 |
| WO2018145193A1 (en) | 2017-02-10 | 2018-08-16 | Novadaq Technologies ULC | Open-field handheld fluorescence imaging systems and methods |
| NZ755628A (en) * | 2017-02-13 | 2023-09-29 | Codexis Inc | Engineered phenylalanine ammonia lyase polypeptides |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH453269A4 (pt) * | 1968-03-29 | 1973-01-31 | ||
| IT1096208B (it) * | 1978-05-12 | 1985-08-26 | Snam Progetti | Composizione adatta alla riduzione del tenore di fenilalanina e metodo impiegante la stessa |
| FR2523445A1 (fr) * | 1982-03-17 | 1983-09-23 | Sanofi Sa | Nouveaux conjugues associant, par liaison covalente, une enzyme et un anticorps, et associations medicamenteuses utilisant lesdits conjugues |
-
1993
- 1993-06-25 DK DK93755A patent/DK75593D0/da not_active Application Discontinuation
-
1994
- 1994-06-09 EP EP94919559A patent/EP0703788B1/en not_active Expired - Lifetime
- 1994-06-09 US US08/556,963 patent/US5753487A/en not_active Expired - Lifetime
- 1994-06-09 DK DK94919559T patent/DK0703788T3/da active
- 1994-06-09 AU AU70675/94A patent/AU7067594A/en not_active Abandoned
- 1994-06-09 WO PCT/DK1994/000224 patent/WO1995000171A1/en active IP Right Grant
- 1994-06-09 AT AT94919559T patent/ATE209044T1/de not_active IP Right Cessation
- 1994-06-09 CA CA002165281A patent/CA2165281A1/en not_active Abandoned
- 1994-06-09 DE DE69429167T patent/DE69429167T2/de not_active Expired - Lifetime
- 1994-06-09 ES ES94919559T patent/ES2168297T3/es not_active Expired - Lifetime
- 1994-06-09 PT PT94919559T patent/PT703788E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU7067594A (en) | 1995-01-17 |
| EP0703788B1 (en) | 2001-11-21 |
| US5753487A (en) | 1998-05-19 |
| DK75593D0 (pt) | 1993-06-25 |
| DE69429167D1 (de) | 2002-01-03 |
| CA2165281A1 (en) | 1995-01-05 |
| ES2168297T3 (es) | 2002-06-16 |
| DK0703788T3 (da) | 2002-05-21 |
| DE69429167T2 (de) | 2002-07-04 |
| ATE209044T1 (de) | 2001-12-15 |
| EP0703788A1 (en) | 1996-04-03 |
| WO1995000171A1 (en) | 1995-01-05 |
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