CA2153071C - Derivatized calcitonins - Google Patents

Derivatized calcitonins Download PDF

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Publication number
CA2153071C
CA2153071C CA002153071A CA2153071A CA2153071C CA 2153071 C CA2153071 C CA 2153071C CA 002153071 A CA002153071 A CA 002153071A CA 2153071 A CA2153071 A CA 2153071A CA 2153071 C CA2153071 C CA 2153071C
Authority
CA
Canada
Prior art keywords
compound according
calcitonin
group
human
sct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002153071A
Other languages
English (en)
French (fr)
Other versions
CA2153071A1 (en
Inventor
Virender Labroo
Tomikazu Sasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Zymogenetics Inc
Original Assignee
University of Washington
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington, Zymogenetics Inc filed Critical University of Washington
Publication of CA2153071A1 publication Critical patent/CA2153071A1/en
Application granted granted Critical
Publication of CA2153071C publication Critical patent/CA2153071C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57527Calcitonin gene related peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/585Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002153071A 1992-12-31 1993-12-30 Derivatized calcitonins Expired - Fee Related CA2153071C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99974992A 1992-12-31 1992-12-31
US07/999,749 1992-12-31
PCT/US1993/012692 WO1994015962A2 (en) 1992-12-31 1993-12-30 Derivatized calcitonins

Publications (2)

Publication Number Publication Date
CA2153071A1 CA2153071A1 (en) 1994-07-21
CA2153071C true CA2153071C (en) 2000-05-30

Family

ID=25546645

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002153071A Expired - Fee Related CA2153071C (en) 1992-12-31 1993-12-30 Derivatized calcitonins

Country Status (9)

Country Link
EP (1) EP0677062A1 (ja)
JP (1) JPH08505393A (ja)
KR (1) KR100310280B1 (ja)
AU (1) AU673237B2 (ja)
CA (1) CA2153071C (ja)
FI (1) FI953255A (ja)
NO (1) NO952608L (ja)
NZ (1) NZ261052A (ja)
WO (1) WO1994015962A2 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962270A (en) 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1806135A1 (de) * 1967-11-09 1969-07-17 Ciba Geigy Neue hypocalcaemische Peptide und Verfahren zu ihrer Herstellung
US3956260A (en) * 1967-11-09 1976-05-11 Ciba-Geigy Corporation Hypocalcaemic peptides and processes for their manufacture
CH523868A (de) * 1969-10-22 1972-06-15 Ciba Geigy Ag Verfahren zur Herstellung neuer Dotriacontapeptidamide und ihrer Derivate
HUT44794A (en) * 1985-12-04 1988-04-28 Sandoz Ag Process for production of calcitonine-derivatives and medical preparatives containing such compounds
EP0297159A1 (en) * 1987-07-01 1989-01-04 Armour Pharmaceutical Company [N-Acyl, 1,7-Di-Aline] calcitonins, method for their preparation, pharmaceutical compositions and use
DE3876022T2 (de) * 1987-07-08 1993-04-22 Mitsubishi Petrochemical Co Calcitonin-derivate und deren salze.

Also Published As

Publication number Publication date
FI953255A0 (fi) 1995-06-30
FI953255A (fi) 1995-06-30
WO1994015962A2 (en) 1994-07-21
JPH08505393A (ja) 1996-06-11
AU5962994A (en) 1994-08-15
AU673237B2 (en) 1996-10-31
WO1994015962A3 (en) 1994-09-29
CA2153071A1 (en) 1994-07-21
KR100310280B1 (ko) 2002-02-28
NO952608D0 (no) 1995-06-29
EP0677062A1 (en) 1995-10-18
NZ261052A (en) 1997-10-24
NO952608L (no) 1995-08-30
KR960700273A (ko) 1996-01-19

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