CA2147609A1 - Cephem compounds, and their pharmaceutical compositions - Google Patents

Cephem compounds, and their pharmaceutical compositions

Info

Publication number
CA2147609A1
CA2147609A1 CA002147609A CA2147609A CA2147609A1 CA 2147609 A1 CA2147609 A1 CA 2147609A1 CA 002147609 A CA002147609 A CA 002147609A CA 2147609 A CA2147609 A CA 2147609A CA 2147609 A1 CA2147609 A1 CA 2147609A1
Authority
CA
Canada
Prior art keywords
cephem
vinyl
compound
pyridin
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002147609A
Other languages
English (en)
French (fr)
Inventor
Kohji Kawabata
Takeshi Terasawa
Ayako Nakamura
Hideko Nakamura
Fumiyuki Shirai
Kazuo Sakane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929222291A external-priority patent/GB9222291D0/en
Priority claimed from GB939314495A external-priority patent/GB9314495D0/en
Application filed by Individual filed Critical Individual
Publication of CA2147609A1 publication Critical patent/CA2147609A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
CA002147609A 1992-10-23 1993-10-19 Cephem compounds, and their pharmaceutical compositions Abandoned CA2147609A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9314495.4 1992-07-12
GB929222291A GB9222291D0 (en) 1992-10-23 1992-10-23 New cephem compounds
GB9222291.8 1992-10-23
GB939314495A GB9314495D0 (en) 1993-07-12 1993-07-12 New cephem compounds

Publications (1)

Publication Number Publication Date
CA2147609A1 true CA2147609A1 (en) 1994-05-11

Family

ID=26301852

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002147609A Abandoned CA2147609A1 (en) 1992-10-23 1993-10-19 Cephem compounds, and their pharmaceutical compositions

Country Status (9)

Country Link
EP (1) EP0665847A1 (show.php)
JP (1) JPH08502513A (show.php)
KR (1) KR950704331A (show.php)
CN (1) CN1144222A (show.php)
CA (1) CA2147609A1 (show.php)
IL (1) IL107359A0 (show.php)
MX (1) MX9306572A (show.php)
TW (1) TW255894B (show.php)
WO (1) WO1994010177A1 (show.php)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE354577T1 (de) 1996-11-06 2007-03-15 Basilea Pharmaceutica Ag Vinylpyrrolidinon-cephalosporin-derivate
TW415949B (en) * 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents
JP4100908B2 (ja) * 1999-07-30 2008-06-11 エーザイ・アール・アンド・ディー・マネジメント株式会社 塩基性抗生物質・無機酸塩の製造法およびシュウ酸塩中間体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
JPH0686463B2 (ja) * 1988-07-01 1994-11-02 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤

Also Published As

Publication number Publication date
IL107359A0 (en) 1994-01-25
WO1994010177A1 (en) 1994-05-11
MX9306572A (es) 1994-04-29
TW255894B (show.php) 1995-09-01
EP0665847A1 (en) 1995-08-09
CN1144222A (zh) 1997-03-05
JPH08502513A (ja) 1996-03-19
KR950704331A (ko) 1995-11-17

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Legal Events

Date Code Title Description
FZDE Discontinued