CA2141056C - Traitement contre les infections dentoalveolaires au moyen de taurolidine et (ou) de taurultam - Google Patents

Traitement contre les infections dentoalveolaires au moyen de taurolidine et (ou) de taurultam Download PDF

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Publication number
CA2141056C
CA2141056C CA002141056A CA2141056A CA2141056C CA 2141056 C CA2141056 C CA 2141056C CA 002141056 A CA002141056 A CA 002141056A CA 2141056 A CA2141056 A CA 2141056A CA 2141056 C CA2141056 C CA 2141056C
Authority
CA
Canada
Prior art keywords
taurolidine
dental
taurultam
infection
emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002141056A
Other languages
English (en)
Other versions
CA2141056A1 (fr
Inventor
Rolf Wilhelm Pfirrmann
Peter Geistlich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ed Geistlich Soehne AG fuer Chemische Industrie
Original Assignee
Ed Geistlich Soehne AG fuer Chemische Industrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ed Geistlich Soehne AG fuer Chemische Industrie filed Critical Ed Geistlich Soehne AG fuer Chemische Industrie
Publication of CA2141056A1 publication Critical patent/CA2141056A1/fr
Application granted granted Critical
Publication of CA2141056C publication Critical patent/CA2141056C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002141056A 1992-07-30 1993-07-29 Traitement contre les infections dentoalveolaires au moyen de taurolidine et (ou) de taurultam Expired - Lifetime CA2141056C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9216155.3 1992-07-30
GB929216155A GB9216155D0 (en) 1992-07-30 1992-07-30 Treatment of dentoalveolar infections
PCT/GB1993/001607 WO1994003174A1 (fr) 1992-07-30 1993-07-29 Traitement d'infections dento-alveolaires avec la taurolidine et/ou le taurultam

Publications (2)

Publication Number Publication Date
CA2141056A1 CA2141056A1 (fr) 1994-02-17
CA2141056C true CA2141056C (fr) 2005-02-15

Family

ID=10719520

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002141056A Expired - Lifetime CA2141056C (fr) 1992-07-30 1993-07-29 Traitement contre les infections dentoalveolaires au moyen de taurolidine et (ou) de taurultam

Country Status (5)

Country Link
EP (1) EP0652753A1 (fr)
JP (1) JPH07509483A (fr)
CA (1) CA2141056C (fr)
GB (1) GB9216155D0 (fr)
WO (1) WO1994003174A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100517210B1 (ko) * 1994-12-12 2006-06-07 오메로스 코포레이션 통증,염증및경련억제용관주용액
ATE532530T1 (de) * 1994-12-12 2011-11-15 Omeros Corp Bespüllungslösung und deren verwendung zur perioperativen hemmung von schmerzen, entzündungen und/oder spasmen an einer gefässstruktur
JPH10510540A (ja) * 1994-12-12 1998-10-13 オメロス メディカル システムズ，インコーポレーテッド 灌注用溶液並びに疼痛、炎症及びけいれんの抑制法
CA2265774C (fr) * 1996-06-24 2009-05-05 Bio-Safe Enterprises, Inc. Composition antibacterienne
US5972933A (en) * 1998-01-08 1999-10-26 Ed. Geistlich Sohne Ag Fur Chemische Industrie Method of treating microbial infections
US6166007A (en) * 1998-07-02 2000-12-26 Sodemann; Klaus Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof
EP2332542B1 (fr) * 1999-12-06 2015-02-11 Geistlich Pharma AG Utilisation de taurolidine ou de taurultame pour la fabrication d'un medicament pour traiter des tumeurs
CN100519525C (zh) 1999-12-06 2009-07-29 葛兰素集团有限公司 芳香砜类及其医疗用途
EP1797884B1 (fr) * 1999-12-06 2013-09-11 Geistlich Pharma AG Taurolidine ou de taurultame pour i' utilisation dans le traitement des tumeurs de la prostate, des poumons, du côlon et dans le traitement de la glioblastome multiforme récurrente
US6753328B2 (en) 2001-10-01 2004-06-22 Rhode Island Hospital Methods of inhibiting metastases
DE10261241A1 (de) * 2002-12-20 2004-07-15 3M Espe Ag Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen
DE60311958T2 (de) * 2003-02-03 2007-11-08 Polaschegg, Hans-Dietrich, Dr. Zusammensetzung zur Prävention von Infektionen durch subkutane Prothesen
WO2005115357A2 (fr) * 2004-05-14 2005-12-08 Hans-Dietrich Polaschegg Formulations de taurolidine et administration: traitements thérapeutiques et protection antimicrobienne contre la formation de biofilm bactérien
US7696182B2 (en) 2004-11-02 2010-04-13 Nd Partners, Llc Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin
EP1787627A1 (fr) 2005-11-17 2007-05-23 3M Innovative Properties Company Materiau d`empreinte dentaire antimicrobien
AU2011309832B2 (en) * 2010-09-27 2015-01-15 Geistlich Pharma Ag Antimicrobial dental care preparation
AU2016334086B2 (en) * 2015-10-07 2022-10-20 Cormedix Inc. Skin-penetrating formulation of taurolidine
US11738120B1 (en) 2022-04-14 2023-08-29 Cormedix Inc. Synthesis of taurolidine, purity profiles and polymorphs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH600878A5 (fr) * 1975-04-28 1978-06-30 Gaba Ag
GB1557163A (en) * 1975-06-24 1979-12-05 Geistlich Soehne Ag Dental care preparations
GB8328073D0 (en) * 1983-10-20 1983-11-23 Geistlich Soehne Ag Chemical compounds
EP0521225B1 (fr) * 1991-07-04 1994-10-12 Hawe Neos Dental Dr. H. v. Weissenfluh SA Compositions pharmaceutiques pour le traitement de la parodontose, contenant l'acide clavulanique

Also Published As

Publication number Publication date
EP0652753A1 (fr) 1995-05-17
WO1994003174A1 (fr) 1994-02-17
JPH07509483A (ja) 1995-10-19
GB9216155D0 (en) 1992-09-09
CA2141056A1 (fr) 1994-02-17

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20130730

MKEC Expiry (correction)

Effective date: 20131009